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Scandinavian Journal of Gastroenterology Volume 21, 1986 - Issue sup118
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Original Article

Inhibition of Gastric Acid Secretion by Omeprazole and Ranitidine. Effects on Plasma Gastrin and Gastric Histamine, Histidine Decarboxylase Activity and ECL Cell Density in Normal and Antrectomized Rats

Frank Sundler Departments of Histology and Pharmacology, University of Lund, Sweden
,
Enar Carlsson AB Hässle, Mölndal, Sweden
,
Rolf Hakånson Departments of Histology and Pharmacology, University of Lund, Sweden
,
Håkan Larsson AB Hässle, Mölndal, Sweden
&
Hillevi Mattsson AB Hässle, Mölndal, Sweden
Pages 39-45 | Published online: 08 Jul 2009

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I. M. Modlin, W. Esterline, H. Kim & J. R. Goldenring. (1991) Enterochromaffin-Like Cells and Gastric Argyrophil Carcinoidosis. Acta Oncologica 30:4, pages 493-498.
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H. G. Dammann, M. Dreyer, R. Kangah, P. Müller & B. Simon. (1988) First-Choice Treatment in Uncomplicated Ulcer Disease: A Case for Acid Inhibitors. Scandinavian Journal of Gastroenterology 23:sup153, pages 62-70.
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K. G. Wormsley. (1988) Risks of Therapeutic Achlorhydria. Scandinavian Journal of Gastroenterology 23:sup153, pages 35-51.
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C. B. H. W. Lamers. (1988) Hormonal Regulation of Gastric Acid in Peptic Ulcer Disease. Scandinavian Journal of Gastroenterology 23:sup146, pages 5-10.
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L. F. S. J. Crobach, J. B. M. J. Jansen & C. B. H. W. Lamers. (1988) Effect of Intermittent Weekend Therapy with Omeprazole on Basal and Bombesin- and Pentagastrin-Stimulated Gastric Acid and Serum Gastrin. Scandinavian Journal of Gastroenterology 23:4, pages 407-412.
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T. Lind, C. Cederberg, H. Forssell, M. Olausson & L. Olbe. (1988) Relationship between Reduction of Gastric Acid Secretion and Plasma Gastrin Concentration during Omeprazole Treatment. Scandinavian Journal of Gastroenterology 23:10, pages 1259-1266.
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C. T. Eason, A. Pattison, D. D. Howells, A. J. Spencer & F. W. Bonner. (1988) Assessment of Gastric Antisecretory Effects of Phenoxyisobutyrate Derivatives in the Rat and the Mouse. Scandinavian Journal of Gastroenterology 23:9, pages 1063-1071.
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Articles from other publishers (27)

Reidar Alexander Vigen, Mark Kidd, Irvin M. Modlin, Duan Chen & Chun-Mei Zhao. (2012) Ultrastructure of ECL cells in Mastomys after long-term treatment with H2 receptor antagonist loxtidine. Medical Molecular Morphology 45:2, pages 80-85.
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Graham J. Dockray. 2006. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 91 120 .
Graham Dockray, Rod Dimaline & Andrea Varro. (2004) Gastrin: old hormone, new functions. Pfl�gers Archiv - European Journal of Physiology 449:4, pages 344-355.
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Akihiro HagiwaraYasuko Takesada, Hikaru Tanaka, Seiko Tamano, Masao Hirose, Nobuyuki Ito & Tomoyuki Shirai. (2016) Dose-dependent Induction of Glandular Stomach Preneoplastic and Neoplastic Lesions in Male F344 Rats Treated with Catechol Chronically. Toxicologic Pathology 29:2, pages 180-186.
Crossref
Bakke, Qvigstad, Brenna, Sandvik & Waldum. (2001) Gastrin has a specific proliferative effect on the rat enterochromaffin‐like cell, but not on the parietal cell: A study by elutriation centrifugation. Acta Physiologica Scandinavica 169:1, pages 29-37.
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S. Okabe & Y. Tsukimi. 1997. Biochemical Pharmacology as an Approach to Gastrointestinal Disorders. Biochemical Pharmacology as an Approach to Gastrointestinal Disorders 349 359 .
S. Okabe & Y. Tsukimi. (1996) Does omeprazole-induced hypergastrinaemia contribute to the enhanced healing of aceticacid-induced gastric ulcers in rats?. Inflammopharmacology 4:3, pages 267-277.
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Andreas W. Herling & Klaus Weidmann. 1994. 233 264 .
Jens F. Rehfeld & Wouter W. Van Solinge. 1994. 295 347 .
Lars Werkö. (2009) Problems with Toxicity Studies in the Assessment of New Drugs. International Journal of Technology Assessment in Health Care 9:2, pages 189-201.
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F. von Bruchhausen, S. Ebel, E. Hackenthal, G. Dannhardt, A. W. Frahm, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf & G. Wurm. 1993. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 1221 1293 .
Jens F. Rehfeld & Linda Hilsted. 1992. 239 262 .
R. H. K. Gompertz, W. K. Man, S. K. Li, J. Spencer, J. H. Baron & A. S. Michalowski. (1991) Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model. Agents and Actions 33:1-2, pages 161-163.
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P. N. Maton, G. Sachs & B. Wallmark. 1991. Pharmacology of Peptic Ulcer Disease. Pharmacology of Peptic Ulcer Disease 159 187 .
K. J. Öbrink. 1991. Histamine and Histamine Antagonists. Histamine and Histamine Antagonists 305 324 .
Charles T. Eason, Frank W. Bonner & Dennis V. Parke. (1990) The importance of pharmacokinetic and receptor studies in drug safety evaluation. Regulatory Toxicology and Pharmacology 11:3, pages 288-307.
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Anton J. Bilchik, Ola Nilsson, Irvin M. Modlin, Karl A. Zucker & Thomas E. Adrian. (1990) Significance of gastric endocrine tumor and age-related gut peptide alterations in Mastomys. Regulatory Peptides 27:2, pages 195-207.
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Courtney M. TownsendJrJr, Pomila Singh & James C. Thompson. (1989) Effects of Gastrointestinal Peptides on Gastrointestinal Cancer Growth. Gastroenterology Clinics of North America 18:4, pages 777-791.
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Kenneth G. Wormsley. (1989) Therapeutic achlorhydria and risk of gastric cancer. Gastroenterologia Japonica 24:5, pages 585-596.
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. 1989. Ion Transport. Ion Transport 293 373 .
I. Biemond, L. F. S. J. Crobach, J. B. M. J. Jansen & C. B. H. W. Lamers. (1989) Effect of short-term omeprazole administration of serum pepsinogens in relation to fasting serum gastrin and gastric acid secretion. European Journal of Clinical Pharmacology 37:4, pages 345-349.
Crossref
Rolf Håkanson, Jan Axelson, Rolf Ekman & Frank Sundler. (1988) Hypergastrinaemia evoked by omeprazole stimulates growth of gastric mucosa but not of pancreas or intestines in hamster, guinea pig and chicken. Regulatory Peptides 23:1, pages 105-115.
Crossref
CORNELIS B.H.W. LAMERS & JAN B.M.J. JANSEN. (1988) Hormonal manipulation of gastrointestinal cancer by gut peptides. Journal of Gastroenterology and Hepatology 3:4, pages 379-386.
Crossref
J. M. POLAK & S. R. BLOOM. (2007) Review: the enterochromaffin‐like cell, intragastric acidity and the trophic effect of plasma gastrin. Alimentary Pharmacology & Therapeutics 2:4, pages 291-296.
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G. Chejfec, S. Falkmer, U. Askensten, L. Grimelius & V.E. Gould. (1988) Neuroendocrine Tumors of the Gastrointestinal Tract. Pathology - Research and Practice 183:2, pages 143-154.
Crossref
Robert S. Hirth, Lorraine D. Evans, Robert A. Buroker & Frederick B. Oleson. (2016) Gastric Enterochromaffin-Like Cell Hyperplasia and Neoplasia in the Rat: An Indirect Effect of the Histamine H 2 -Receptor Antagonist, BL-6341 . Toxicologic Pathology 16:2, pages 273-287.
Crossref
Cornelis B.H.W. Lamers & Jan B.M.J. Jansen. (1988) Role of gastrin and cholecystokinin in tumours of the gastrointestinal tract. European Journal of Cancer and Clinical Oncology 24:2, pages 267-273.
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