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Scandinavian Journal of Gastroenterology Volume 22, 1987 - Issue 1
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Original Article

Circulating Tachykinins (Substance P, Neurokinin A, Neuropeptide K) and the Carcinoid Flush

J. M. Conlon Clinical Research Group for Gastrointestinal Endocrinology, the Max-Planck-Gesellschaft, and Dept. of Medicine, University of Gottingen, Gottingen, FRG
,
C. F. Deacon Clinical Research Group for Gastrointestinal Endocrinology, the Max-Planck-Gesellschaft, and Dept. of Medicine, University of Gottingen, Gottingen, FRG
,
G. Richter Clinical Research Group for Gastrointestinal Endocrinology, the Max-Planck-Gesellschaft, and Dept. of Medicine, University of Gottingen, Gottingen, FRG
,
F. Stöckmann Clinical Research Group for Gastrointestinal Endocrinology, the Max-Planck-Gesellschaft, and Dept. of Medicine, University of Gottingen, Gottingen, FRG
&
W. Creutzfeldt Clinical Research Group for Gastrointestinal Endocrinology, the Max-Planck-Gesellschaft, and Dept. of Medicine, University of Gottingen, Gottingen, FRG
Pages 97-105 | Received 22 May 1986, Accepted 05 Sep 1986, Published online: 08 Jul 2009

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R. A. Anderson, K. Skorupskaite & J. Sassarini. (2019) The neurokinin B pathway in the treatment of menopausal hot flushes. Climacteric 22:1, pages 51-54.
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H. Ahlman, B. Wängberg, O. Nilsson, L. Grimelius, G. Granérus, I. M. Modlin, O. Stenqvist & T. Scherstén. (1992) Aspects on Diagnosis and Treatment of the Foregut Carcinoid Syndrome. Scandinavian Journal of Gastroenterology 27:6, pages 459-471.
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L. K. Kvols. (1989) Therapeutic Considerations for the Malignant Carcinoid Syndrome. Acta Oncologica 28:3, pages 433-438.
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A. I. Vinik, N. Thompson, F. Eckhauser & A. R. Moattari. (1989) Clinical Features of Carcinoid Syndrome and the Use of Somatostatin Analogue in Its Management. Acta Oncologica 28:3, pages 389-402.
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Articles from other publishers (37)

Karolina Skorupskaite & Richard A. Anderson. (2022) Hypothalamic neurokinin signalling and its application in reproductive medicine. Pharmacology & Therapeutics 230, pages 107960.
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Richard A. Anderson & Robert P. Millar. (2021) The roles of kisspeptin and neurokinin B in GnRH pulse generation in humans, and their potential clinical application. Journal of Neuroendocrinology.
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L. Maione, S. Christin-Maître, P. Chanson & J. Young. (2017) Contrôle de l’axe gonadotrope : nouveaux aspects physiologiques et thérapeutiques. Annales d'Endocrinologie 78, pages S31-S40.
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Dorothy M Gujral & Sanjeev Bhattacharyya. (2013) Cardiac manifestations of gastrointestinal carcinoid tumor. Future Cardiology 9:4, pages 479-488.
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Chandrasekar Palaniswamy, William H. Frishman & Wilbert S. Aronow. (2012) Carcinoid Heart Disease. Cardiology in Review 20:4, pages 167-176.
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Aaron I. Vinik & Michael Raymund C. Gonzales. (2011) New and Emerging Syndromes due to Neuroendocrine Tumors. Endocrinology and Metabolism Clinics of North America 40:1, pages 19-63.
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S. Tappin, P. Brown & L. Ferasin. (2007) An intestinal neuroendocrine tumour associated with paroxysmal ventricular tachycardia and melaena in a 10-year-old boxer. Journal of Small Animal Practice 0:0, pages 070706190438002-???.
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Wei Hou & Mitchell L. Schubert. (2008) Treatment of gastric carcinoids. Current Treatment Options in Gastroenterology 10:2, pages 123-133.
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J. M. Conlon. 2004. Tachykinins. Tachykinins 25 61 .
FRANCISCO JOSÉ LÓPEZ, PATRICIA D. FINN, MARK A. LAWSON & ANDRÉS NEGRO-VILAR. 2000. Menopause. Menopause 33 60 .
Charlie Makridis, Elvar Theodorsson, Göran Åkerström, Kjell Öberg & Lars Knutson. (2002) Increased intestinal non‐substance P tachykinin concentrations in malignant midgut carcinoid disease. Journal of Gastroenterology and Hepatology 14:5, pages 500-507.
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Rodat T. Cunningham, Kathy M. Pogue, William J. Curry, Colin F. Johnston, James M. Sloan & Keith D. Buchanan. (1999) Immunostaining for vasostatin I distinguishes between ileal and lung carcinoids. The Journal of Pathology 187:3, pages 321-325.
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Allen S. Anderson, Daniel Krauss & Roberto Lang. (1997) Cardiovascular complications of malignant carcinoid disease. American Heart Journal 134:4, pages 693-702.
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Muhammed Ashraf Memon & Heidi Nelson. (1997) Gastrointestinal carcinoid tumors. Diseases of the Colon & Rectum 40:9, pages 1101-1118.
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GERHARD E. FEURLE, MARIT HEGER, ELKE NIEBERGALL‐ROTH, STEPHAN TEYSSEN, MICHAEL FRIED, CHARLOTTE EBERLE, MANFRED V. SINGER & GERD HAMSCHER. (2009) Gastroenteropancreatic effects of xenin in the dog. The Journal of Peptide Research 49:4, pages 324-330.
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Paul C. Neary, Paul H. Redmond, Timothy Houghton, Gordon R. K. Watson & David Bouchier-Hayes. (1997) Carcinoid disease. Diseases of the Colon & Rectum 40:3, pages 349-362.
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Peter Holzer & Ulrike Holzer-Petsche. (1997) Tachykinins in the gut. Part II. Roles in neural excitation, secretion and inflammation. Pharmacology & Therapeutics 73:3, pages 219-263.
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Claude Matuchansky & Jean-Marie Launay. (1995) Serotonin, catecholamines, and spontaneous midgut carcinoid flush: Plasma studies from flushing and nonflushing sites. Gastroenterology 108:3, pages 743-751.
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Stephen T. Meller & G.F. Gebhart. (1993) Silent ischemia: A hypothetical mechanism. Neuroscience & Biobehavioral Reviews 17:2, pages 229-236.
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Stacia Poole & Neil A. Fenske. (1993) Cutaneous markers of internal malignancy. II. Paraneoplastic dermatoses and environmental carcinogens. Journal of the American Academy of Dermatology 28:2, pages 147-164.
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Alessandro Antonelli, C. Gambuzza, R. Bertoni & L. Baschieri. (2014) Calcitonin, as SMS 201–995, ameliorates the VIPoma syndrome. Journal of Endocrinological Investigation 16:1, pages 57-59.
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J. Philippe. (1992) 12 APUDomas: acute complications and their medical management. Baillière's Clinical Endocrinology and Metabolism 6:1, pages 217-228.
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Naomi E. Rance. 1992. The Human Hypothalamus in Health and Disease, Proceedings of the 17th International Summer School of Brain Research, held at the Auditorium of the University of Amsterdam. The Human Hypothalamus in Health and Disease, Proceedings of the 17th International Summer School of Brain Research, held at the Auditorium of the University of Amsterdam 221 236 .
A. Saini & J. Waxman. (1991) Management of carcinoid syndrome.. Postgraduate Medical Journal 67:788, pages 506-508.
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Siobhan J. McGrath-Linden, Colin F. Johnston, Daniel T. O'Connor, Christopher Shaw & Keith D. Buchanan. (1991) Pancreastatin-like immunoreactivity in human carcinoid disease. Regulatory Peptides 33:1, pages 55-70.
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R. ARNOLD. (2008) Therapeutic strategies in the management of endocrine GEP tumours. European Journal of Clinical Investigation 20:1, pages 82-90.
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Aaron I. Vinik, Michael K. McLeod, Lorraine M. Fig, Brahm Shapiro, Ricardo V. Lloyd & Kyung Cho. (1989) Clinical Features, Diagnosis, and Localization of Carcinoid Tumors and Their Management. Gastroenterology Clinics of North America 18:4, pages 865-896.
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Larry K. Kvols. (1989) Therapy of the Malignant Carcinoid Syndrome. Endocrinology and Metabolism Clinics of North America 18:2, pages 557-568.
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H. J. Balks, J. M. Conlon, W. Creutzfeldt & F. Stöckmann. (1989) Effect of a long-acting somatostatin analogue (octreotide) on circulating tachykinins and the pentagastrin-induced carcinoid flush. European Journal of Clinical Pharmacology 36:2, pages 133-137.
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L. K. Kvols. 1989. Sandostatin® in the Treatment of Gastroenteropancreatic Endocrine Tumors. Sandostatin® in the Treatment of Gastroenteropancreatic Endocrine Tumors 65 82 .
Avrum Z. Bluming & Ronald R. Berez. (1988) Successful treatment of unstable angina in malignant carcinoid syndrome using the long-acting somatostatin analogue SMS 201-995 (Sandostatin). The American Journal of Medicine 85:6, pages 872-874.
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Abhiram Sahu, Pushpa S. Kalra, Michael G. Dube & Satya P. Kalra. (1988) Neuropeptide K suppresses feeding in the rat. Regulatory Peptides 23:2, pages 135-143.
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H. J. BALKS, J. M. CONLON, W. CREUTZFELDT & F. STÖCKMANN. (2008) CIRCULATING BRADYKININ‐LIKE IMMUNOREACTIVITY AND THE PENTAGASTRIN‐INDUCED CARCINOID FLUSH. Clinical Endocrinology 29:2, pages 141-151.
Crossref
J. Michael Conlon, Carolyn F. Deacon, Lars Grimelius, Bjorn Cedermark, Richard F. Murphy, Lars Thim & Werner Creutzfeldt. (1988) Neuropeptide K-(1–24)-peptide: Storage and release by carcinoid tumors. Peptides 9:4, pages 859-866.
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H. J. BALKS, L. THIM & J. M. CONLON. (2008) CIRCULATION OF A FRAGMENT OF HAEMOGLOBIN α‐CHAIN DURING A PENTAGASTRIN‐INDUCED FLUSH IN PATIENTS WITH METASTATIC CARCINOID TUMOURS. Clinical Endocrinology 28:3, pages 261-269.
Crossref
D G Grahame-Smith. (1987) What is the cause of the carcinoid flush?. Gut 28:11, pages 1413-1416.
Crossref
Werner Creutzfeldt & Fritz Stöckmann. (1987) Carcinoids and carcinoid syndrome. The American Journal of Medicine 82:5, pages 4-16.
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