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Original Article

Clinical Pharmacology of Tranexamic Acid

Pages 22-25 | Published online: 08 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

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Filippo Alberto Ferrari, Simone Garzon, Ricciarda Raffaelli, Antonella Cromi, Jvan Casarin, Fabio Ghezzi, Stefano Uccella & Massimo Franchi. (2022) Tranexamic acid for the prevention and the treatment of primary postpartum haemorrhage: a systematic review. Journal of Obstetrics and Gynaecology 42:5, pages 734-746.
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Z. Békássy & B. åstedt. (1990) Treatment with the Fibrinolytic Inhibitor Tranexamic Acid—Risk for Thrombosis?. Acta Obstetricia et Gynecologica Scandinavica 69:4, pages 353-354.
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Articles from other publishers (94)

Dênis Antonio Ferrarin, Marcelo Luís Schwab, Mathias Reginatto Wrzesinski, Júlia da Silva Rauber, Julya Nathalya Felix Chaves, Angel Ripplinger & Alexandre Mazzanti. (2024) Tranexamic Acid in Reducing Intraoperative Bleeding in Dogs Undergoing Thoracolumbar and Lumbar Hemilaminectomy and Intervertebral Disc Fenestration. Topics in Companion Animal Medicine 58, pages 100820.
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Filippo Alberto Ferrari, Simone Garzon Garz, Francesca Cisotto, Stefano Uccella & Massimo Franchi. (2023) What is the Role of Tranexamic Acid in the Management of Postpartum Haemorrhage? State of Art and Perspectives. Current Women s Health Reviews 19:4.
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Yeonsoo S. Lee, Anna S. Jenkins, Giovanni Gonzalez-Albo, Colleen T. Ball, Steven B. Porter & Chandler D. Dora. (2023) Tranexamic Acid Was Not Associated With a Reduction in Bleeding Complications Related to Holmium Laser Enucleation of the Prostate. Urology 180, pages 209-213.
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Anne-Sophie Bouthors, Sixtine Gilliot, Loïc Sentilhes, Benjamin Hennart, Emmanuelle Jeanpierre, Catherine Deneux-Tharaux, Gilles Lebuffe & Pascal Odou. (2022) The role of tranexamic acid in the management of postpartum haemorrhage. Best Practice & Research Clinical Anaesthesiology 36:3-4, pages 411-426.
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Prakash A. Patel, Julie A. Wyrobek, Alexander J. Butwick, Evan G. Pivalizza, Gregory M. T. Hare, C. David Mazer & Susan M. Goobie. (2022) Update on Applications and Limitations of Perioperative Tranexamic Acid. Anesthesia & Analgesia 135:3, pages 460-473.
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Panagiotis Masouros, Georgia Antoniou & Vasileios S. Nikolaou. (2022) Efficacy and safety of tranexamic acid in hip fracture surgery. How does dosage affect outcomes: A meta-analysis of randomized controlled trials. Injury 53:2, pages 294-300.
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Isabelle Denry, Jean‐Marie Nédélec & Julie A. Holloway. (2021) Tranexamic acid‐loaded hemostatic nanoclay microsphere frameworks. Journal of Biomedical Materials Research Part B: Applied Biomaterials 110:2, pages 422-430.
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Carlos A. Batagello, Fabio C. Vicentini, Manoj Monga, Aaron W. Miller, Giovanni S. Marchini, Fabio C.M. Torricelli, Alexandre Danilovic, Rafael F. Coelho, Miguel Srougi, Willian C. Nahas & Eduardo Mazzucchi. (2021) Tranexamic acid in patients with complex stones undergoing percutaneous nephrolithotomy: a randomised, double‐blinded, placebo‐controlled trial. BJU International 129:1, pages 35-47.
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Vladimir V. Yurukov, Tracy Boykin & Megan A. Rech. (2022) Tranexamic Acid for the Treatment of Acute Gastrointestinal Bleeding in a Jehovah's Witness Patient on Apixaban and Dual Antiplatelet Therapy. Advanced Emergency Nursing Journal 44:1, pages 11-18.
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Vitaley Kovalev, Fanglong Dong, Sina Bagheri, David Wong & Matthew Wi. (2021) Effectiveness of Tranexamic Acid in Reducing Hemorrhage in Isolated Blunt Solid Organ Injury. Cureus.
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Bing-xin Kang, Hui Xu, Chen-xin Gao, Sheng Zhong, Jing Zhang, Jun Xie, Song-tao Sun, Ying-hui Ma, Xi-rui Xu, Chi Zhao, Wei-tao Zhai, Lian-bo Xiao & Xiao-jun Gao. (2021) Multiple intravenous tranexamic acid doses in total knee arthroplasty in patients with rheumatoid arthritis: a randomized controlled study. BMC Musculoskeletal Disorders 22:1.
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Jordan Fuzi, Gideon R. Budiono, Catherine Meller & Ian Jacobson. (2021) Tranexamic acid in otorhinolaryngology – A contemporary review. World Journal of Otorhinolaryngology - Head and Neck Surgery 7:4, pages 328-337.
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Brett L. Houston, Dean A. Fergusson, Jamie Falk, Emily Krupka, Iris Perelman, Rodney H. Breau, Daniel I. McIsaac, Emily Rimmer, Donald S. Houston, Allan Garland, Robert E. Ariano, Alan Tinmouth, Robert Balshaw, Alexis F. Turgeon, Eric Jacobsohn & Ryan Zarychanski. (2021) Prophylactic tranexamic acid use in non‐cardiac surgeries at high risk for transfusion. Transfusion Medicine 31:4, pages 236-242.
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Yuki Miyamoto, Hiroyuki Ohbe, Miho Ishimaru, Hiroki Matsui, Kiyohide Fushimi & Hideo Yasunaga. (2020) Effect of tranexamic acid in patients with colonic diverticular bleeding: A nationwide inpatient database study. Journal of Gastroenterology and Hepatology 36:4, pages 999-1005.
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Arnaud Lechien, David Faraoni & Philippe Van der Linden. (2021) Effective tranexamic acid concentration for 95% inhibition of tissue-type plasminogen activator-induced hyperfibrinolysis in full-term pregnant women: a prospective interventional study. Blood Coagulation & Fibrinolysis 32:3, pages 186-193.
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Zhenghao Wang, Xiao He, Yunjin Bai & Jia Wang. (2020) Can tranexamic acid reduce the blood transfusion rate in patients undergoing percutaneous nephrolithotomy? A systematic review and meta-analysis. Journal of International Medical Research 48:4, pages 030006052091756.
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Xiangwei Yuan, Jiaxing Wang, Qiaojie Wang & Xianlong Zhang. (2018) Synergistic effects of intravenous and intra‐articular tranexamic acid on reducing hemoglobin loss in revision total knee arthroplasty: a prospective, randomized, controlled study. Transfusion 58:4, pages 982-988.
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M. J. Madurska, K. A. Sachse, J. O. Jansen, T. E. Rasmussen & J. J. Morrison. (2017) Fibrinolysis in trauma: a review. European Journal of Trauma and Emergency Surgery 44:1, pages 35-44.
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Orlando D. Sabbag, Matthew P. Abdel, Adam W. Amundson, Dirk R. Larson & Mark W. Pagnano. (2017) Tranexamic Acid Was Safe in Arthroplasty Patients With a History of Venous Thromboembolism: A Matched Outcome Study. The Journal of Arthroplasty 32:9, pages S246-S250.
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H.K. Ahmadzia, E.L. Lockhart, S.M. Thomas, I.J. Welsby, M.R. Hoffman, A.H. James, A.P. Murtha, G.K. Swamy & C.A. Grotegut. (2017) Using antifibrinolytics in the peripartum period – concern for a hypercoagulable effect?. Journal of Neonatal-Perinatal Medicine 10:1, pages 1-7.
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Abhishek Gadre & James K. Stoller. (2017) Tranexamic Acid for Hemoptysis: A Review. Clinical Pulmonary Medicine 24:2, pages 69-74.
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Priyankur Roy, M. S. Sujatha, Ambarisha Bhandiwad & Bivas Biswas. (2016) Role of Tranexamic Acid in Reducing Blood Loss in Vaginal Delivery. The Journal of Obstetrics and Gynecology of India 66:S1, pages 246-250.
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Snir Heller, Eric Secrist, Alisina Shahi, Antonia F. Chen & Javad Parvizi. (2016) Tranexamic Acid Can Be Administered to Arthroplasty Patients Who Receive Aspirin for Venous Thromboembolic Prophylaxis. The Journal of Arthroplasty 31:7, pages 1437-1441.
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Gunavathi Kandappan & Anand B. (2016) EFFICACY OF TRANEXAMIC ACID IN DECREASING BLOOD LOSS DURING AND AFTER CAESAREAN SECTION IN MULTIGRAVIDA PARTURIENTS: A CASE CONTROLLED PROSPECTIVE STUDY. Journal of Evidence Based Medicine and Healthcare 3:48, pages 2419-2425.
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