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Scandinavian Journal of Gastroenterology Volume 22, 1987 - Issue sup136
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Original Article

A Pharmacokinetic Profile of Nizatidine in Man

J. T. Callaghan Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
R. F. Bergstrom Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
A. Rubin Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
S. Chernish Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
R. Crabtree Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
M. P. Knadler Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
B. Obermeyer Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
W. W. Offen Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
D. W. Schneck Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
,
G. Aronoff Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
&
K. C. Lasseter Lilly Research Laboratories, Lilly Laboratory for Clinical Research, and Indiana University School of Medicine, Dept. of Medicine and Pharmacology, Indianapolis, Indiana, USA; Clinical Pharmacology Associates, Miami, Florida, USA
 show all
Pages 9-17 | Published online: 08 Jul 2009

Citations (36)

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F. Parente & G. Bianchi Porro. (1994) Acid Inhibitory Characteristics of Nizatidine in Man: An Overview. Scandinavian Journal of Gastroenterology 29:sup206, pages 3-7.
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Articles from other publishers (35)

Steffen Pockes & Katharina Tropmann. (2021) Histamine H 2 receptor radioligands: triumphs and challenges . Future Medicinal Chemistry 13:12, pages 1073-1081.
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Seung-Woo ParkYeon-Jeong HeoKyu-Sun LeeJae-Woo Kwon. (2019) A case of nizatidine-induced immediate hypersensitivity. Allergy, Asthma & Respiratory Disease 7:2, pages 106.
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Iraj Hosseini, Anita Gajjala, Daniela Bumbaca Yadav, Siddharth Sukumaran, Saroja Ramanujan, Ricardo Paxson & Kapil Gadkar. (2018) gPKPDSim: a SimBiology®-based GUI application for PKPD modeling in drug development. Journal of Pharmacokinetics and Pharmacodynamics 45:2, pages 259-275.
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Kari M. Morrissey, Sophie L. Stocker, Eugene C. Chen, Richard A. Castro, Claire M. Brett & Kathleen M. Giacomini. (2015) The Effect of Nizatidine, a MATE2K Selective Inhibitor, on the Pharmacokinetics and Pharmacodynamics of Metformin in Healthy Volunteers. Clinical Pharmacokinetics 55:4, pages 495-506.
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De-Wei Shang, Zhan-Zhang Wang, Xiao-Jia Ni, Ming Zhang, Jin-Qing Hu, Chang Qiu & Yu-Guan Wen. (2015) Development and validation of a sensitive LC–MS/MS assay for the quantification of nizatidine in human plasma and urine and its application to pharmacokinetic study. Journal of Chromatography B 998-999, pages 80-87.
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Joseph V. Turner, Beverly D. Glass & Snezana Agatonovic-Kustrin. (2003) Prediction of drug bioavailability based on molecular structure. Analytica Chimica Acta 485:1, pages 89-102.
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D. Memis, A. Turan, B. Karamanlioglu, T. Guler, A. Yurdakoc, Z. Pamukcu & N. Turan. (2019) Effect of Preoperative Oral Use of Erythromycin and Nizatidine on Gastric pH and Volume. Anaesthesia and Intensive Care 30:4, pages 428-432.
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Mikihiro Tsutsumi, Yasuhiro Ueshima & Shujiro Takase. (2001) Pharmacokinetics of roxatidine acetate in patients with chronic liver disease. Journal of Gastroenterology and Hepatology 16:8, pages 910-915.
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Shigeki Saima, Hirotoshi Echizen, Keiko Yoshimoto & Takashi Ishizaki. (2013) Hemofiltrability of Histamine H 2 ‐Receptor Antagonist, Nizatidine, and its Metabolites in Patients with Renal Failure . The Journal of Clinical Pharmacology 33:4, pages 324-329.
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F. von Bruchhausen, S. Ebel, E. Hackenthal, G. Dannhardt, A. W. Frahm, U. Holzgrabe, K. Keller, E. Nürnberg, H. Rimpler, G. Schneider, P. Surmann, H. U. Wolf & G. Wurm. 1993. Hagers Handbuch der Pharmazeutischen Praxis. Hagers Handbuch der Pharmazeutischen Praxis 1057 1220 .
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M. T. POPAT, O. J. DYAR & C. E. BLOGG. (2007) Comparison of the effects of oral nizatidine and ranitidine on gastric volume and pH in patients undergoing gynaecological laparoscopy. Anaesthesia 46:10, pages 816-819.
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Norman H. Gilinsky. (1990) Peptic Ulcer Disease in the Elderly. Gastroenterology Clinics of North America 19:2, pages 255-271.
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A. Tracqui, P. Kintz & P. Mangin. (1990) Determination of nizatidine and two of its main metabolites in human serum using high-performance liquid chromatography. Journal of Chromatography B: Biomedical Sciences and Applications 529, pages 369-376.
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J. P. Desager & C. Harvengt. (2016) Oral Bioavailability of Nizatidine and Ranitidine Concurrently Administered with Antacid. Journal of International Medical Research 17:1, pages 62-67.
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Rudolf Arnold, Hanns-Gerd Dammann, Peter Minartz, Hans-Dieter Peters & Bernd Simon. 1989. Nizatidin. Nizatidin 83 92 .
Jean-Pierre Aymard, Bernadette Aymard, Patrick Netter, Bernard Bannwarth, Philippe Trechot & François Streiff. (2012) Haematological Adverse Effects of Histamine H2-Receptor Antagonists. Medical Toxicology 3:6, pages 430-448.
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S Lanzon-Miller, R E Pounder, N A Chronos, F Raymond, M R Hamilton & D Dalgleish. (1988) Twenty four hour intragastric acidity and plasma gastrin concentration in healthy volunteers taking nizatidine 150 mg, nizatidine 300 mg, ranitidine 300 mg, or placebo at 21:00 h.. Gut 29:10, pages 1364-1369.
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Roy Pounder. (1988) Histamine H2-receptor antagonists. Baillière's Clinical Gastroenterology 2:3, pages 593-608.
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D. R. Forsyth, K. S. A. Jayasinghe & C. J. C. Roberts. (1988) Do nizatidine and cimetidine interact with ibuprofen?. European Journal of Clinical Pharmacology 35:1, pages 85-88.
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A. Tracqui, P. Kintz, P. Kreissig, P. Mangin, A. A. Lugnier & A. J. Chaumont. (2004) HPLC-Bestimmung von Nizatidin in Serum und UrinHPLC determination of nizatidine in serum and urine. Fresenius' Zeitschrift für analytische Chemie 332:5, pages 468-469.
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