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Scandinavian Journal of Gastroenterology Volume 23, 1988 - Issue 8
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Original Article

Comparison of 5-Aminosalicylic Acid (3 g) and Prednisolone Phosphate Sodium Enemas (30 mg) in the Treatment of Distal Ulcerative Colitis: A Prospective, Randomized, Double-Blind Trial

C. J. J. Mulder Division of Gastroenterology, Pharmacy and Pathology, Academic Medical Center, Amsterdam, The Netherlands
,
G. N. J. Tytgat Division of Gastroenterology, Pharmacy and Pathology, Academic Medical Center, Amsterdam, The Netherlands
,
E. H. H. Wiltink Division of Gastroenterology, Pharmacy and Pathology, Academic Medical Center, Amsterdam, The Netherlands
&
H.-J. Houthoff Division of Gastroenterology, Pharmacy and Pathology, Academic Medical Center, Amsterdam, The Netherlands
Pages 1005-1008 | Received 02 Mar 1988, Accepted 25 May 1988, Published online: 08 Jul 2009

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B. A. Jacobsen, K. Abildgaard, H. H. Rasmussen, L. A. Christensen, J. Fallingborg, S. H. Hansen & S. Nørby Rasmussen. (1991) Availability of Mesalazine (5-Aminosalicylic Acid) from Enemas and Suppositories during Steady-State Conditions. Scandinavian Journal of Gastroenterology 26:4, pages 374-378.
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Articles from other publishers (34)

Bénédicte Caron, William J Sandborn, Remo Panaccione, Stefan Schreiber, Ailsa Hart, Virginia Solitano, Silvio Danese & Laurent Peyrin-Biroulet. (2022) Efficacy of Pharmacological Agents for Ulcerative Proctitis: A Systematic Literature Review. Journal of Crohn's and Colitis 16:6, pages 922-930.
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Tim Raine, Stefanos Bonovas, Johan Burisch, Torsten Kucharzik, Michel Adamina, Vito Annese, Oliver Bachmann, Dominik Bettenworth, Maria Chaparro, Wladyslawa Czuber-Dochan, Piotr Eder, Pierre Ellul, Catarina Fidalgo, Gionata Fiorino, Paolo Gionchetti, Javier P Gisbert, Hannah Gordon, Charlotte Hedin, Stefan Holubar, Marietta Iacucci, Konstantinos Karmiris, Konstantinos Katsanos, Uri Kopylov, Peter L Lakatos, Theodore Lytras, Ivan Lyutakov, Nurulamin Noor, Gianluca Pellino, Daniele Piovani, Edoardo Savarino, Francesco Selvaggi, Bram Verstockt, Antonino Spinelli, Yves Panis & Glen Doherty. (2022) ECCO Guidelines on Therapeutics in Ulcerative Colitis: Medical Treatment. Journal of Crohn's and Colitis 16:1, pages 2-17.
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Bénédicte Caron, William J Sandborn, Stefan Schreiber, Remo Panaccione, Silvio Danese & Laurent Peyrin-Biroulet. (2021) Drug development for ulcerative proctitis: current concepts. Gut 70:7, pages 1203-1209.
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Robert Battat, Marjolijn Duijvestein, Leonardo Guizzetti, Daksh Choudhary, Brigid S. Boland, Parambir S. Dulai, Claire E. Parker, Tran M. Nguyen, Siddharth Singh, Niels Vande Casteele, Rish K. Pai, Brian G. Feagan, William J. Sandborn & Vipul Jairath. (2019) Histologic Healing Rates of Medical Therapies for Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. American Journal of Gastroenterology 114:5, pages 733-745.
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Cynthia W. Ko, Siddharth Singh, Joseph D. Feuerstein, Corinna Falck-Ytter, Yngve Falck-Ytter, Raymond K. Cross, Seth Crockett, Yngve Falck-Ytter, Joseph Feuerstein, Steven Flamm, John Inadomi, Cynthia Ko, Thiruvengadam Muniraj, Robert O’Shea, John Pandolfino, Amit Patel, Ravi Sharaf, Shazia Siddique, Grace Su, Kenneth Wang & Adam Weizman. (2019) AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis. Gastroenterology 156:3, pages 748-764.
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Siddharth Singh, Joseph D. Feuerstein, David G. Binion & William J. Tremaine. (2019) AGA Technical Review on the Management of Mild-to-Moderate Ulcerative Colitis. Gastroenterology 156:3, pages 769-808.e29.
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Jian Zeng, Lin Lv & Zhe-Chuan Mei. (2017) Budesonide foam for mild to moderate distal ulcerative colitis: A systematic review and meta-analysis. Journal of Gastroenterology and Hepatology 32:3, pages 558-566.
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Kirstin Taylor & Peter R. Gibson. 2017. Crohn's Disease and Ulcerative Colitis. Crohn's Disease and Ulcerative Colitis 399 412 .
Seymour Katz. 2014. Medical Therapy of Ulcerative Colitis. Medical Therapy of Ulcerative Colitis 121 133 .
Wojciech Blonski, David Kotlyar & Gary R. Lichtenstein. 2011. Inflammatory Bowel Disease. Inflammatory Bowel Disease 73 92 .
John K Marshall, Marroon Thabane, A Hillary Steinhart, Jamie R Newman, Anju Anand & E Jan Irvine. (2010) Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database of Systematic Reviews.
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J. MENDOZA, J. LEGIDO, S. RUBIO & J. P. GISBERT. (2007) Systematic review: the adverse effects of sodium phosphate enema. Alimentary Pharmacology & Therapeutics 26:1, pages 9-20.
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William J. Sandborn. 2005. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 605 629 .
Philippe Seksik, Jean-François Contou, Philippe Ducrotté, Jean-Luc Faucheron & Vincent De Parades. (2004) Traitement de la rectocolite ulcéro-hémorragique dans sa forme distale. Gastroentérologie Clinique et Biologique 28:10, pages 964-973.
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Philippe Marteau, Laurent Beaugerie, Yoram Bouhnik, Bernard Flourié, Luc Gambiez, Jean-Marie Reimund & Philippe Seksik. (2004) Introduction de l’argumentaire. Gastroentérologie Clinique et Biologique 28:10, pages 961-963.
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William J. Sandborn. 2003. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 605 629 .
Stephen Hanauer, Larry I Good, Michael W Goodman, Ronald J Pizinger, Williamson B Strum, Carl Lyss, Gregory Haber, Noel C Williams & Malcolm Robinson. (2000) Long-Term Use of Mesalamine (Rowasa) Suppositories in Remission Maintenance of Ulcerative Proctitis. American Journal of Gastroenterology 95:7, pages 1749-1754.
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John K Marshall & Jan E Irvine. (2000) Putting Rectal 5-Aminosalicylic Acid in Its Place: The Role in Distal Ulcerative Colitis. American Journal of Gastroenterology 95:7, pages 1628-1636.
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Russell D Cohen, Douglas M Woseth, Ronald A Thisted & Stephen B Hanauer. (2000) A Meta-Analysis and Overview of The Literature on Treatment Options for Left-Sided Ulcerative Colitis and Ulcerative Proctitis. American Journal of Gastroenterology 95:5, pages 1263-1276.
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Fernando Hintz Greca, Maria de Lourdes Pessole Biondo-Simões, Sergio Ioshi, Eduardo A. Andrade dos Santos, Eduardo Wei Kin Chin, Imad Izat El Tawil & Fábio Lúcio Stalhschmidt. (2000) Cicatrização de anastomoses do cólon esquerdo com doença inflamatória: estudo experimental em ratos. Acta Cirurgica Brasileira 15:suppl 3, pages 41-46.
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G d'Albasio, P Paoluzi, M Campieri, Bianchi G Porro, A Pera, C Prantera, G C Sturniolo & M Miglioli. (1998) Maintenance Treatment of Ulcerative Proctitis With Mesalazine Suppositories: A Double-Blind Placebo-Controlled Trial. American Journal of Gastroenterology 93:5, pages 799-803.
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H. M. Van Dullemen & G. N. J. Tytgat. 1997. Procedures in Hepatogastroenterology. Procedures in Hepatogastroenterology 317 329 .
Samir A. Shah & Mark A. Peppercorn. (2012) A Comparative Review of Topical Therapies for Inflammatory Bowel Disease. Clinical Immunotherapeutics 6:2, pages 117-129.
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Barbara S. Kirschner. (1996) ULCERATIVE COLITIS IN CHILDREN. Pediatric Clinics of North America 43:1, pages 235-254.
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J. K. MARSHALL & E. J. IRVINE. (2007) Rectal aminosalicylate therapy for distal ulcerative colitis: a meta‐analysis. Alimentary Pharmacology & Therapeutics 9:3, pages 293-300.
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Alain Bitton & Mark A. Peppercorn. (1995) Medical Therapy of Ulcerative Proctitis and Proctosigmoiditis, Including Refractory Disease. Inflammatory Bowel Diseases 1:3, pages 207-219.
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D. W. Hommes, S. A. Radema, J. Jansen, F. Smit, P. Fockens, Y. Zhao, M. Ceska, G. N. J. Tytgat & S. J. H. van Deventer. (1995) Production and Cellular Source of Interleukin-8 in Ulcerative Colitis. Inflammatory Bowel Diseases 1:2, pages 108-116.
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C. J. J. MULDER & G. N. J. TYTGAT. (2007) Review article: topical corticosteroids in inflammatory bowel disease. Alimentary Pharmacology & Therapeutics 7:2, pages 125-130.
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M. P. SHARMA, H. V. DUPHARE & S. DASARATHY. (1992) A prospective randomized double blind trial comparing prednisolone and 4-aminosalicylic acid enemas in acute distal ulcerative colitis. Journal of Gastroenterology and Hepatology 7:2, pages 173-177.
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H. Huchzermeyer. 1992. Glukokortikoide bei ausgewählten Indikationen. Glukokortikoide bei ausgewählten Indikationen 88 111 .
R. Fiasse. (1991) Effete immunologiques et anti-inflammatoires des médicaments utilisés dans le traitement des maladies inflammatoires idiopathiques de ľintestinImmunological and anti-inflammatory actions of drugs used in the treatment of inflammatory bowel diseaseEfectos inmunológicos y anti-inflamatorios de medicamentos utilizados en el tratamiento de enfermedades inflamatorias idiopáticas intestinales. Acta Endoscopica 21:2, pages 261-274.
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A M Zaitoun, I Cobden, H al Mardini & C O Record. (1991) Morphometric studies in rectal biopsy specimens from patients with ulcerative colitis: effect of oral 5 amino salicylic acid and rectal prednisolone treatment.. Gut 32:2, pages 183-187.
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Lloyd R. Sutherland. (1990) Topical Treatment of Ulcerative Colitis. Medical Clinics of North America 74:1, pages 119-131.
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L. M. L. Stolk, M. Gerrits, E. H. H. Wiltink, C. J. J. Mulder & G. N. J. Tytgat. (1989) Formulation and stability of a beclomethasone dipropionate enema. Pharmaceutisch Weekblad Scientific Edition 11:1, pages 20-22.
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