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Original Article

Treatment with Cimetidine, Antacid, or Placebo in Patients with Dyspepsia of Unknown Origin

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Pages 7-18 | Received 11 Mar 1987, Accepted 24 Jul 1987, Published online: 08 Jul 2009

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Read on this site (21)

H.-D. Allescher, A. Böckenhoff, G. Knapp, M. Wienbeck, J. Hartung. (2001) Treatment of Non-Ulcer Dyspepsia: a Meta-Analysis of Placebo-Controlled Prospective Studies. Scandinavian Journal of Gastroenterology 36:9, pages 934-941.
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P. G. Farup, S. Wetterhus, M. Osnes & K. Ulshagen. (1997) Ranitidine Effectively Relieves Symptoms in a Subset of Patients with Functional Dyspepsia. Scandinavian Journal of Gastroenterology 32:8, pages 755-759.
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I. Wiklund. (1995) Aspects of Quality of Life in Gastrointestinal Disease: Some Methodological Issues. Scandinavian Journal of Gastroenterology 30:sup208, pages 129-132.
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F. Halter, B. Miazza & R. Brignoli. (1994) Cisapride or Cimetidine in the Treatment of Functional Dyspepsia: Results of a Double-Blind Randomized, Swiss Multicentre Study. Scandinavian Journal of Gastroenterology 29:7, pages 618-623.
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Terje Johannessen, Hermod Petersen, Pål Kristensen, Per Martin Kleveland, Jan Dybdahl, Arne K. Sandvik, Eiliv Brenna And & Helge Waldum. (1993) The intensity and variability of symptoms in dyspepsia. Scandinavian Journal of Primary Health Care 11:1, pages 50-55.
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H. J. A. Jebbink, A. J. P. M. Smout & G. P. Van Berge-Henegouwen. (1993) Pathophysiology and Treatment of Functional Dyspepsia. Scandinavian Journal of Gastroenterology 28:sup200, pages 8-14.
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C. ó'moráin & J. Gilvarry. (1993) Eradication of Helicobacter pylori in Patients with Non-Ulcer Dyspepsia. Scandinavian Journal of Gastroenterology 28:sup196, pages 30-33.
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H. Gudjónsson, E. Oddsson, S. Björnsson, Ó. Gunnlaugsson, Á. Theodors, T. Á. Jónasson, O. Bonnevie & B. Thjodleifsson. (1993) Efficacy of Sucralfate in Treatment of Non-Ulcer Dyspepsia: A Double-Blind Placebo-Controlled Study. Scandinavian Journal of Gastroenterology 28:11, pages 969-972.
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A. I. Morris. (1992) The Success of Histamine-2 Receptor Antagonists. Scandinavian Journal of Gastroenterology 27:sup194, pages 71-75.
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T. Hausken &A. Berstad. (1992) Cisapride Treatment of Patients with Non-Ulcer Dyspepsia and Erosive Prepyloric Changes a Double-Blind, Placebo-Controlled Trial. Scandinavian Journal of Gastroenterology 27:3, pages 213-217.
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T. Johannessen, H. Petersen, P. Kristensen, D. Fosstvedt, P. M. Kleveland, J. Dybdahl &I. Løge. (1992) Cimetidine On-Demand in Dyspepsia Experience with Randomized Controlled Single-Subject Trials. Scandinavian Journal of Gastroenterology 27:3, pages 189-195.
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O. Nyrén. (1991) Therapeutic Trial in Dyspepsia: Its Role in the Primary Care Setting. Scandinavian Journal of Gastroenterology 26:sup182, pages 61-69.
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N. J. T. Alley. (1991) Drug Treatment of Functional Dyspepsia. Scandinavian Journal of Gastroenterology 26:sup182, pages 47-60.
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O. Nyrén. (1991) Secretary Abnormalities in Functional Dyspepsia. Scandinavian Journal of Gastroenterology 26:sup182, pages 25-28.
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P. G. Farup, S. Larsen, K. Ulshagen & M. Osnes. (1991) Ranitidine for Non-Ulcer Dyspepsia: A Clinical Study of the Symptomatic Effect of Ranitidine and a Classification and Characterization of the Responders to Treatment. Scandinavian Journal of Gastroenterology 26:11, pages 1209-1216.
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T. Johannessen, P. Kristensen, H. Petersen, D. Fosstvedt, I. Løge, P. M. Kleveland & J. Dybdahl. (1991) The Symptomatic Effect of 1-Day Treatment Periods with Cimetidine in Dyspepsia Combined Results from Randomized, Controlled, Single-Subject Trials. Scandinavian Journal of Gastroenterology 26:9, pages 974-980.
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G. Sene-Larsen, Aa. Nesland & A. Berstad. (1989) Follow-up Study of Erosive Prepyloric Changes. Scandinavian Journal of Gastroenterology 24:4, pages 430-433.
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K.-Å Jönsson, R. Gotthard, G. Bodemar & U. Brodin. (1989) The Clinical Relevance of Endoscopic and Histologic Inflammation of Gastroduodenal Mucosa in Dyspepsia of Unknown Origin. Scandinavian Journal of Gastroenterology 24:4, pages 385-395.
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S. N. Parr. (1989) Chewable cimetidine versus chewable antacid in dyspepsia: Which provides faster pain relief?. Current Medical Research and Opinion 11:9, pages 557-566.
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Alexander C. Ford, Paul Moayyedi, Christopher J. Black, Yuhong Yuan, Sajesh K. Veettil, Sanjiv Mahadeva, Kirati Kengkla, Nathorn Chaiyakunapruk & Yeong Yeh Lee. (2020) Systematic review and network meta-analysis: efficacy of drugs for functional dyspepsia. Alimentary Pharmacology & Therapeutics.
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Angelita C Melo, Antonio Mendes, Carla Serra, Cassyano Correr, Hellen Maniero, José Ruben Bonfim, Josélia Frade, Juliana Ferreira, Michel Otuki, Thaís Teles de Souza & Wálleri Reis. 2020. Guia de prática clínica: sinais e sintomas do trato gastrointestinal: azia (acidez/pirose) e dispepsia. Guia de prática clínica: sinais e sintomas do trato gastrointestinal: azia (acidez/pirose) e dispepsia.
Kouichi Sakurai & Hiroko Suda. 2018. Functional Dyspepsia. Functional Dyspepsia 129 138 .
B. E. Lacy, N. J. Talley, G. R. LockeIIIIII, E. P. Bouras, J. K. DiBaise, H. B. El‐Serag, B. P. Abraham, C. W. Howden, P. Moayyedi & C. Prather. (2012) Review article: current treatment options and management of functional dyspepsia. Alimentary Pharmacology & Therapeutics 36:1, pages 3-15.
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Hye-Kyung JungSu Jin HongYunju JoSeong Woo JeonYu Kyung ChoKwang Jae LeeJoon Seong LeeHyo Jin ParkEin Soon ShinSun Hee LeeSang-Uk Han. (2012) Updated Guidelines 2012 for Gastroesophageal Reflux Disease. The Korean Journal of Gastroenterology 60:4, pages 195.
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Benoit Coffin, Claude Bortolloti, Odile Bourgeois & Luc Denicourt. (2011) Efficacy of a simethicone, activated charcoal and magnesium oxide combination (Carbosymag®) in functional dyspepsia: Results of a general practice-based randomized trial. Clinics and Research in Hepatology and Gastroenterology 35:6-7, pages 494-499.
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D. Ang, N. J. Talley, M. Simren, P. Janssen, G. Boeckxstaens & J. Tack. (2011) Review article: endpoints used in functional dyspepsia drug therapy trials. Alimentary Pharmacology & Therapeutics 33:6, pages 634-649.
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Paul Moayyedi, Soo Shelly, Jonathan J Deeks, Brendan Delaney, Michael Innes & David Forman. (2011) Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database of Systematic Reviews.
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Sam Ryong JeeHye-Kyung JungByung Hoon MinKee Don ChoiPoong-Lyul RheeYoung Woo KangSang In Lee. (2011) Guidelines for the Treatment of Functional Dyspepsia. The Korean Journal of Gastroenterology 57:2, pages 67.
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Smita L.S. Halder & Nicholas J. Talley. (2008) Functional dyspepsia: A new Rome III paradigm. Current Treatment Options in Gastroenterology 10:4, pages 259-272.
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Paul Moayyedi, Soo Shelly, Jonathan J Deeks, Brendan Delaney, Michael Innes & David Forman. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
R. J. SAAD & W. D. CHEY. (2006) Review article: current and emerging therapies for functional dyspepsia. Alimentary Pharmacology and Therapeutics 24:3, pages 475-492.
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Nicholas J. Talley, Nimish B. Vakil & Paul Moayyedi. (2005) American Gastroenterological Association Technical Review on the Evaluation of Dyspepsia. Gastroenterology 129:5, pages 1756-1780.
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Smita L. S. Halder & Nicholas J. Talley. (2005) Treatment of functional dyspepsia. Current Treatment Options in Gastroenterology 8:4, pages 325-336.
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Ahmed Madisch. (2005) Management of functional dyspepsia: Unsolved problems and new perspectives. World Journal of Gastroenterology 11:42, pages 6577.
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Silvia Delgado-Aros, Filippo Cremonini & Nicholas J. Talley. (2004) Treatment of functional dyspepsia. Current Treatment Options in Gastroenterology 7:2, pages 121-131.
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N. S. Abraham, P. Moayyedi, B. Daniels & S. J. O. Veldhuyzen Van Zanten. (2004) The methodological quality of trials affects estimates of treatment efficacy in functional (non-ulcer) dyspepsia. Alimentary Pharmacology & Therapeutics 19:6, pages 631-641.
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P. Moayyedi, S. Soo, J. Deeks, D. Forman, A. Harris, M. Innes & B. Delaney. (2003) Systematic review: antacids, H 2 -receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia . Alimentary Pharmacology & Therapeutics 17:10, pages 1215-1227.
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&NA;. (2002) Prokinetic agents may be the best drug choice for non-ulcer dyspepsia in the elderly. Drugs & Therapy Perspectives 18:11, pages 13-16.
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N. J. Talley, D. S. Riff, H. Schwartz & S. P. Marcuard. (2008) Double‐blind placebo‐controlled multicentre studies of rebamipide, a gastroprotective drug, in the treatment of functional dyspepsia with or without Helicobacter pylori infection . Alimentary Pharmacology & Therapeutics 15:10, pages 1603-1611.
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H. A. Redstone, N. Barrowman & S. J. O. Veldhuyzen Van Zanten. (2001) H 2 -receptor antagonists in the treatment of functional (nonulcer) dyspepsia: a meta-analysis of randomized controlled clinical trials . Alimentary Pharmacology & Therapeutics 15:9, pages 1291-1299.
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Peter Bytzer & Nicholas J. Talley. (2001) Current indications for acid suppressants in dyspepsia. Best Practice & Research Clinical Gastroenterology 15:3, pages 385-400.
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Maxwell A. Asante. (2001) Optimal Management of Patients With Non-Ulcer Dyspepsia. Drugs & Aging 18:11, pages 819-826.
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C.C. Tan. (1999) How I Manage the Dyspeptic Patient and Non-Ulcer Dyspepsia. Journal of the Royal College of Physicians of Edinburgh 29:2, pages 153-158.
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