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Original Article

Optimal Assessment of Gastrointestinal Side Effects Induced by Non-Steroidal Anti-Inflammatory Drugs: Endoscopic Lesions, Faecal Blood Loss, and Symptoms Not Necessarily Correlated, As Observed after Naproxen and Oxindanac in Healthy Volunteers

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Pages 1007-1013 | Published online: 08 Jul 2009

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T. R. Meling, L. Aabakken, A. Røseth & M. Osnes. (1996) Faecal Calprotectin Shedding after Short-Term Treatment with Non-Steroidal Anti-Inflammatory Drugs. Scandinavian Journal of Gastroenterology 31:4, pages 339-344.
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Odd Vinje, Hans E. Fagertun, Even Laerum, Henrik Lund & Stig Larsen. (1993) Ketoprofen controlled release (CR) in the treatment of osteoarthrosis; a double blind, randomized multicentre study of single morning versus evening dose. Scandinavian Journal of Primary Health Care 11:2, pages 91-97.
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L. Aabakken & M. Osnes. (1990) Gastroduodenal Lesions Induced by Naproxen: An Endoscopic Evaluation of Regional Differences and Natural Course. Scandinavian Journal of Gastroenterology 25:12, pages 1215-1222.
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L. Aabakken, J. H. Dybdahl, S. Larsen, P. Mowinckel, M. Osnes & H. Quiding. (1989) A Double-blind Comparison of Gastrointestinal Effects of Ibuprofen Standard and Ibuprofen Sustained Release Assessed by Means of Endoscopy and 51Cr-labelled Erythrocytes. Scandinavian Journal of Rheumatology 18:5, pages 307-313.
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Articles from other publishers (17)

Kathrine Rydén Suther, Einar Hopp, Bjarne Smevik, Arnt Eltvedt Fiane, Harald Lauritz Lindberg, Stig Larsen & Charlotte de Lange. (2018) Can visual analogue scale be used in radiologic subjective image quality assessment?. Pediatric Radiology 48:11, pages 1567-1575.
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Won Suk Lee, Jang Young Lee, Won Young Sung & Sang Won Seo. (2014) Naproxen-induced methemoglobinemia in an alcohol-dependent patient. The American Journal of Emergency Medicine 32:11, pages 1439.e9-1439.e10.
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K. D. RainsfordK. D. Rainsford. 2012. Ibuprofen: Pharmacology, Therapeutics and Side Effects. Ibuprofen: Pharmacology, Therapeutics and Side Effects 123 139 .
K. D. Rainsford. (2009) Ibuprofen: pharmacology, efficacy and safety. Inflammopharmacology 17:6, pages 275-342.
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Fazlul Huq. (2006) Molecular Modelling Analysis of the Metabolism of Naproxen. Journal of Pharmacology and Toxicology 1:4, pages 346-353.
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Hiroyuki Yokoyama, Toshiharu Horie & Shoji Awazu. (2006) Naproxen-induced oxidative stress in the isolated perfused rat liver. Chemico-Biological Interactions 160:2, pages 150-158.
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Evros Vassiliou, Vikas Sharma, Huie Jing, Farzad Sheibanie & Doina Ganea. (2004) Prostaglandin E2 Promotes the Survival of Bone Marrow-Derived Dendritic Cells. The Journal of Immunology 173:11, pages 6955-6964.
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Simon Smale & Ingvar Bjarnason. (2003) Determining small bowel integrity following drug treatment. British Journal of Clinical Pharmacology 56:3, pages 284-291.
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Jia-Qing Huang, Subbaramiah Sridhar & Richard H Hunt. (1999) Gastrointestinal safety profile of nabumetone: a meta-analysis. The American Journal of Medicine 107:6, pages 55-61.
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Michael W. LeachDoyle W. Frank, Mark R. Berardi, Ellen W. Evans, Robert C. Johnson, David G. Schuessler, Elaine Radwanski & Mark E. Cartwright. (2016) Renal Changes Associated with Naproxen Sodium Administration in Cynomolgus Monkeys. Toxicologic Pathology 27:3, pages 295-306.
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S. Scharf, R. Kwiatek, A. Ugoni & N. Christophidis. (2008) NSAIDs and faecal blood loss in elderly patients with osteoarthritis: is plasma half‐life relevant?. Australian and New Zealand Journal of Medicine 28:4, pages 436-439.
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A. Van Hecken, Μ. Depré, Κ. Wynants, Η. Vanbilloen, A. Verbruggen, J. Arnout, Ph. Vanhove, R. Cariou & P.J. De Schepper. (1998) Effect of Clopidogrel on Naproxen-Induced Gastrointestinal Blood Loss in Healthy Volunteers. Drug Metabolism and Drug Interactions 14:3.
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Albert Cohen. (1995) Gastrointestinal blood loss induced by bromfenac sodium, aspirin, and placebo. Clinical Therapeutics 17:6, pages 1110-1117.
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Hiroyuki Yokoyama, Toshiharu Horie & Shoji Awazu. (1995) Oxidative stress in isolated rat hepatocytes during naproxen metabolism. Biochemical Pharmacology 49:7, pages 991-996.
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Yokoyama Hiroyuki, Horie Toshiharu & Awazu Shoji. (1993) Lipid peroxidation in rat liver microsomes during naproxen metabolism. Biochemical Pharmacology 45:8, pages 1721-1724.
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William Dillin & Gurvinder S. Uppal. (1992) Analysis of Medications Used in the Treatment of Cervical Disk Degeneration. Orthopedic Clinics of North America 23:3, pages 421-433.
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A. Del Favero, L. Patoia & L. Santucci. 1992. Side-Effects of Anti-Inflammatory Drugs 3. Side-Effects of Anti-Inflammatory Drugs 3 43 53 .

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