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Scandinavian Journal of Gastroenterology Volume 25, 1990 - Issue 10
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Original Article

Misoprostol Treatment Exacerbates Abdominal Discomfort in Patients with Non-Ulcer Dyspepsia and Erosive Prepyloric Changes: A Double-Blind, Placebo-Controlled, Multicentre Study

T. Hausken Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
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G. Stene-Larsen Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
,
O. Lange Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
,
O. Aronsen Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
,
T. Nerdrum Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
,
F. Hegbom Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
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T. Schulz Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
&
A. Berstad Medical Dept., Haukeland Hospital, Bergen; Medical Dept., Lovisenberg Hospital, Oslo; Medical Dept., Molde Hospital, Molde; Medical Dept., Hammerfest Hospital, Hammerfest; Medical Dept., Askim Hospital, Askim, Norway
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Pages 1028-1033 | Received 18 Jan 1990, Accepted 06 Apr 1990, Published online: 08 Jul 2009

Citations (23)

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Jørgen Valeur, Mette Helvik Morken, Elisabeth Norin, Tore Midtvedt & Arnold Berstad. (2009) Carbohydrate intolerance in patients with self-reported food hypersensitivity: Comparison of lactulose and glucose. Scandinavian Journal of Gastroenterology 44:12, pages 1416-1423.
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Johan A. Lunding, Solomon Tefera, Odd Helge Gilja, Trygve Hausken, Alfred Bayati, Hans Rydholm, Hillevi Mattsson & Arnold Berstad. (2006) Rapid initial gastric emptying and hypersensitivity to gastric filling in functional dyspepsia: Effects of duodenal lipids. Scandinavian Journal of Gastroenterology 41:9, pages 1028-1036.
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Johanna I. Westbrook, Jean H. McIntosh, Nicholas J. Talley. (2000) The Impact of Dyspepsia Definition on Prevalence Estimates: Considerations for Future Researchers. Scandinavian Journal of Gastroenterology 35:3, pages 227-233.
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G. S. Sandha, R. H. Hunt, S. J. O. Veldhuyzen van Zanten. (1999) A Systematic Overview of the Use of Diary Cards, Quality-of-Life Questionnaires, and Psychometric Tests in Treatment Trials of Helicobacter pylori-Positive and -Negative Non-Ulcer Dyspepsia. Scandinavian Journal of Gastroenterology 34:3, pages 244-249.
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T. Hausken &A. Berstad. (1992) Cisapride Treatment of Patients with Non-Ulcer Dyspepsia and Erosive Prepyloric Changes a Double-Blind, Placebo-Controlled Trial. Scandinavian Journal of Gastroenterology 27:3, pages 213-217.
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Articles from other publishers (18)

D. Ang, N. J. Talley, M. Simren, P. Janssen, G. Boeckxstaens & J. Tack. (2011) Review article: endpoints used in functional dyspepsia drug therapy trials. Alimentary Pharmacology & Therapeutics 33:6, pages 634-649.
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Paul Moayyedi, Soo Shelly, Jonathan J Deeks, Brendan Delaney, Michael Innes & David Forman. (2011) Pharmacological interventions for non-ulcer dyspepsia. Cochrane Database of Systematic Reviews.
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Kine GregersenRagna A. LindTormod BjørkkjaerLivar FrøylandArnold BerstadGulen Arslan Lied. (2008) Effects of Seal Oil on Meal-Induced Symptoms and Gastric Accommodation in Patients with Subjective Food Hypersensitivity: A Pilot Study. Clinical Medicine. Gastroenterology 1, pages CGast.S1028.
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Paul Moayyedi, Soo Shelly, Jonathan J Deeks, Brendan Delaney, Michael Innes & David Forman. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
T. Liebregts, B. Adam & G. Holtmann. (2006) Funktionelle Dyspepsie – eine Verlegenheitsdiagnose?Functional dyspepsia – diagnosis of desperation?. Der Internist 47:6, pages 568-577.
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Nicholas J. Talley, Nimish B. Vakil & Paul Moayyedi. (2005) American Gastroenterological Association Technical Review on the Evaluation of Dyspepsia. Gastroenterology 129:5, pages 1756-1780.
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Ahmed Madisch. (2005) Management of functional dyspepsia: Unsolved problems and new perspectives. World Journal of Gastroenterology 11:42, pages 6577.
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M. Koch, A. Dezi, M. Tarquini & L. Capurso. (2000) Prevention of non-steroidal anti-inflammatory drug-induced gastrointestinal mucosal injury: risk factors for serious complications. Digestive and Liver Disease 32:2, pages 138-151.
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C.J. Hawkey. (2000) Management of gastroduodenal ulcers caused by non-steroidal anti-inflammatory drugs. Best Practice & Research Clinical Gastroenterology 14:1, pages 173-192.
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Ivar S�nb� Kristiansen, Tore Kristian Kvien & Erik Nord. (1999) Cost effectiveness of replacing diclofenac with a fixed combination of misoprostol and diclofenac in patients with rheumatoid arthritis. Arthritis & Rheumatism 42:11, pages 2293-2302.
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C.C. Tan. (1999) How I Manage the Dyspeptic Patient and Non-Ulcer Dyspepsia. Journal of the Royal College of Physicians of Edinburgh 29:2, pages 153-158.
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Fermín Mearin, Agustín Balboa, Natalia Zárate, Mercedes Cucala & Juan-R Malagelada. (1999) Placebo in Functional Dyspepsia: Symptomatic, Gastrointestinal Motor, and Gastric Sensorial Responses. American Journal of Gastroenterology 94:1, pages 116-125.
Crossref
N. J. TALLEY. (2007) Review article: functional dyspepsia—should treatment be targeted on disturbed physiology?. Alimentary Pharmacology & Therapeutics 9:2, pages 107-115.
Crossref
H. G. DAMMANN, J. SIMON‐SCHULTZ, I. STEINHOFF, A. DAMASCHKE, A. SCHMOLDT & E. SALLOWSKY. (2012) Differential effects of misoprostol and ranitidine on the pharmacokinetics of diclofenac and gastrointestinal symptoms. British Journal of Clinical Pharmacology 36:4, pages 345-349.
Crossref
G. RICHARD LOCKE & NICHOLAS J. TALLEY. (2008) Management of non‐ulcer dyspepsia. Journal of Gastroenterology and Hepatology 8:3, pages 279-286.
Crossref
Charles J Steadman. (1992) Prophylaxis against NSAID‐induced ulcers. Medical Journal of Australia 157:11, pages 801-803.
Crossref
Alastair J.J. Wood & Robert P. Walt. (1992) Misoprostol for the Treatment of Peptic Ulcer and Antiinflammatory-Drug–Induced Gastroduodenal Ulceration. New England Journal of Medicine 327:22, pages 1575-1580.
Crossref
M. J. KENDALL, R. GIBSON & R. P. WALT. (2007) Co‐administration of misoprostol or ranitidine with indomethacin: effects on pharmacokinetics, abdominal symptoms and bowel habit. Alimentary Pharmacology & Therapeutics 6:4, pages 437-446.
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