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Original Article

A Model of Cholestasis in the Rat, Using a Microsurgical Technique

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Pages 10-14 | Received 11 May 1992, Accepted 21 Jul 1992, Published online: 08 Jul 2009

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M. A. Aller, M. P. Nava, J. L. Arias, M. Durán, I. Prieto, M. A. Llamas & J. Arias. (2004) Microsurgical Extrahepatic Cholestasis in the Rat: A Long-Term Study. Journal of Investigative Surgery 17:2, pages 99-104.
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Articles from other publishers (27)

Lourdes Rodríguez-Fragoso, Anahí Rodríguez-López & Janet Sánchez-Quevedo. 2023. Animal Models and Experimental Research in Medicine. Animal Models and Experimental Research in Medicine.
Jaciara Fernanda Gomes Gama, Liana Monteiro da Fonseca Cardoso, Jussara Machado Lagrota-Candido & Luiz Anastacio Alves. (2022) Animal models applied to acute-on-chronic liver failure: Are new models required to understand the human condition?. World Journal of Clinical Cases 10:9, pages 2687-2699.
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Jaciara Fernanda Gomes Gama, Liana Monteiro da Fonseca Cardoso, Jussara Machado Lagrota-Candido & Luiz Anastacio Alves. (2022) Animal models applied to acute-on-chronic liver failure: Are new models required to understand the human condition?. World Journal of Clinical Cases 10:9, pages 2685-2697.
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María-Ángeles Aller, Vicente Martínez, Ana Arias, Maria-Paz Nava, Valentín Cuervas-Mons, Patri Vergara & Jaime Arias. (2019) Mast cell-mediated splanchnic cholestatic inflammation. Clinics and Research in Hepatology and Gastroenterology 43:5, pages 561-574.
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Maria-Angeles Aller, Natalia Arias, Javier Blanco-Rivero & Jaime Arias. (2019) Metabolism in Acute-On-Chronic Liver Failure: The Solution More than the Problem. Archives of Medical Research 50:5, pages 271-284.
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Laura Caracuel, Esther Sastre, Pablo Llévenes, Isabel Prieto, Tania Funes, Mª Ángeles Aller, Jaime Arias, Gloria Balfagón & Javier Blanco-Rivero. (2019) Acute-on-chronic liver disease enhances phenylephrine-induced endothelial nitric oxide release in rat mesenteric resistance arteries through enhanced PKA, PI3K/AKT and cGMP signalling pathways. Scientific Reports 9:1.
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P. Königshofer, K. Brusilovskaya, P. Schwabl & T. Reiberger. (2019) Animal models of portal hypertension. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865:5, pages 1019-1030.
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Carlos Gilsanz, Maria-Angeles Aller, Sherezade Fuentes-Julian, Isabel Prieto, Alejandro Blázquez-Martinez, Salvador Argudo, Jorge Fernández-Delgado, Jose Beleña, Jaime Arias & María P. De Miguel. (2017) Adipose-derived mesenchymal stem cells slow disease progression of acute-on-chronic liver failure. Biomedicine & Pharmacotherapy 91, pages 776-787.
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Esther Sastre, Laura Caracuel, Isabel Prieto, Pablo Llévenes, M. Ángeles Aller, Jaime Arias, Gloria Balfagón & Javier Blanco-Rivero. (2016) Decompensated liver cirrhosis and neural regulation of mesenteric vascular tone in rats: role of sympathetic, nitrergic and sensory innervations. Scientific Reports 6:1.
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Maria-Angeles Aller, Natalia Heras, Javier Blanco-Rivero, Jose-Ignacio Arias, Vicente Lahera, Gloria Balfagón & Jaime Arias. (2012) Portal hypertensive cardiovascular pathology: The rescue of ancestral survival mechanisms?. Clinics and Research in Hepatology and Gastroenterology 36:1, pages 35-46.
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Maria-Angeles Aller. (2012) A half century (1961-2011) of applying microsurgery to experimental liver research. World Journal of Hepatology 4:7, pages 199.
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Maria-Angeles Aller, Natalia Arias, Isabel Prieto, Luis Santamaria, Maria-Paz de Miguel, Jorge-Luis Arias & Jaime Arias. (2012) Portal hypertension-related inflammatory phenotypes: From a vitelline and amniotic point of view. Advances in Bioscience and Biotechnology 03:07, pages 881-899.
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José García-Dominguez, María-Angeles Aller, Cruz García, Felipe de Vicente, Maria-Teresa Corcuera, Fernando Gómez-Aguado, María José Alonso, Elena Vara & Jaime Arias. (2010) Splanchnic Th2 and Th1 Cytokine Redistribution in Microsurgical Cholestatic Rats. Journal of Surgical Research 162:2, pages 203-212.
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M. A. Aller, I. Prieto, S. Argudo, F. de Vicente, L. Santamaría, M. P. de Miguel, J. L. Arias & J. Arias. (2010) The Interstitial Lymphatic Peritoneal Mesothelium Axis in Portal Hypertensive Ascites: When in Danger, Go Back to the Sea. International Journal of Inflammation 2010, pages 1-18.
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Maria-Angeles Aller, Marta Mendez, Maria-Paz Nava, Laudino Lopez, Jorge-Luis Arias & Jaime Arias. (2009) The value of microsurgery in liver research. Liver International 29:8, pages 1132-1140.
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Maria-Angeles Aller, Jorge-Luis Arias, Isabel Prieto, Manuel Losada & Jaime Arias. (2009) Bile duct ligation: step-by-step to cholangiocyte inflammatory tumorigenesis. European Journal of Gastroenterology & Hepatology, pages 1.
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María-Angeles Aller, Jorge-Luis Arias, Jose García-Domínguez, Jose-Ignacio Arias, Manuel Durán & Jaime Arias. (2008) Experimental obstructive cholestasis: the wound-like inflammatory liver response. Fibrogenesis & Tissue Repair 1:1.
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M.A. Aller, E. Vara, C. García, M. Méndez, M. Méndez-López, I. Mejía, L. López, J.L. Arias & J. Arias. (2008) Prehepatic portal hypertension worsens the enterohepatic redox balance in thioacetamide-cirrhotic rats. Pathophysiology 15:4, pages 233-242.
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Fernando Sánchez‐Patán, Raquel Anchuelo, María‐Teresa Corcuera, Isabel Casado, Fernando Gómez‐Aguado, María‐Angeles Aller, Arturo Cruz, María‐José Alonso & Jaime Arias. (2008) Biliary fibrosis in microsurgical extrahepatic cholestasis in the rat. Microsurgery 28:5, pages 361-366.
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María-Angeles Aller, Jorge-Luis Arias, Arturo Cruz & Jaime Arias. (2007) Inflammation: a way to understanding the evolution of portal hypertension. Theoretical Biology and Medical Modelling 4:1.
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María-Angeles Aller, Jorge-Luis Arias & Jaime Arias. (2007) The mast cell integrates the splanchnic and systemic inflammatory response in portal hypertension. Journal of Translational Medicine 5:1.
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Juan G Abraldes. (2006) Animal models of portal hypertension. World Journal of Gastroenterology 12:41, pages 6577.
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J.G. Abraldes & J.C. García-Pagán. (2006) Modelos animales en el estudio de la hipertensión portal. Gastroenterología y Hepatología 29:1, pages 51-59.
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L.M. García-Moreno, N.M. Conejo, H. González-Pardo, M.A. Aller, M.P. Nava, J. Arias & J.L. Arias. (2005) Evaluation of two experimental models of hepatic encephalopathy in rats. Brazilian Journal of Medical and Biological Research 38:1, pages 127-132.
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Maria Angeles Aller, Manuel Duran, Luis Ortega, Jorge Luis Arias, Maria Paz Nava, Isabel Prieto & Jaime Arias. (2004) Comparative study of macro‐ and microsurgical extrahepatic cholestasis in the rat. Microsurgery 24:6, pages 442-447.
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Ashwin Rumalla, Bret T. Petersen, Todd H. Baron, Lawrence J. Burgart, Lori J. Herman, Maurits J. Wiersema & Christopher J. Gostout. (2003) Development of a swine model for benign stenosis of the bile duct by endoscopic application of intraluminal thermal injury. Gastrointestinal Endoscopy 57:1, pages 73-77.
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Yicheng Ni, Gregorius Lukito, Prof.Dr. Guy Marchal, Erwin Cresens, Jie Yu, Carine Petré, Albert L. Baert & Johan Fevery. (1994) Potential role of bile duct collaterals in the recovery of the biliary obstruction: Experimental study in rats using microcholangiography, histology, serology and magnetic resonance imaging. Hepatology 20:6, pages 1557-1566.
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