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Original Article

Comparison between the Lactulose/Mannitol and 51Cr-Ethylenediaminetetraacetic Acid/14C-Mannitol Methods for Intestinal Permeability Frequency Distribution Pattern and Variability of Markers and Marker Ratios in Healthy Subjects

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Pages 274-280 | Received 12 Jun 1992, Accepted 29 Sep 1992, Published online: 08 Jul 2009

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Lucas Wauters, Luka Van Oudenhove, Alison Accarie, Karlien Geboers, Hannelore Geysen, Joran Toth, Anja Luypaerts, Kristin Verbeke, Tamara Smokvina, Jeroen Raes, Jan Tack & Tim Vanuytsel. (2022) Lactobacillus rhamnosus CNCM I-3690 decreases subjective academic stress in healthy adults: a randomized placebo-controlled trial. Gut Microbes 14:1.
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P. Suenaert, V. Bulteel, E. Den Hond, B. Geypens, F. Monsuur, A. Luypaerts, Y. Ghoos & P. Rutgeerts. (2003) In vivo Influence of Nicotine on Human Basal and NSAID-induced Gut Barrier Function. Scandinavian Journal of Gastroenterology 38:4, pages 399-408.
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S. M. Riordan, C. J. McIver, D. H. Thomas, V. M. Duncombe, T. D. Bolin & M. C. Thomas. (1997) Luminal Bacteria and Small-Intestinal Permeability. Scandinavian Journal of Gastroenterology 32:6, pages 556-563.
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H. Öman, Å. E. K. Henriksson, S. G. O. Johansson & L. Blomquist. (1996) Detection of Naproxen-Induced Intestinal Permeability Change May Be Facilitated by Adding a Standardized Meal but Not by Forming Marker Ratios. Scandinavian Journal of Gastroenterology 31:12, pages 1182-1188.
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J. Lysgård Madsen, O. Scharff, A. Rabøl & O. Worm Krogsgaard. (1996) Relationship between Small-Intestinal Transit Rate and Intestinal Absorption of 14C-labelled Mannitol and 51Cr-labelled Ethylenediaminetetraacetic Acid in Healthy Subjects. Scandinavian Journal of Gastroenterology 31:3, pages 254-259.
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H. Öman, L. Blomquist, Å. E. K. Henriksson & S. G. O. Johansson. (1995) Comparison of Polysucrose 15000, 51Cr-labelled Ethylenediaminetetraacetic Acid, and 14C-Mannitol as Markers of Intestinal Permeability in Man. Scandinavian Journal of Gastroenterology 30:12, pages 1172-1177.
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Articles from other publishers (8)

Ivana R. Sequeira, Marlena C. Kruger, Roger D. Hurst & Roger G. Lentle. (2022) A Simple, Robust, and Convenient HPLC Assay for Urinary Lactulose and Mannitol in the Dual Sugar Absorption Test. Molecules 27:9, pages 2677.
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Lucas Wauters, Matthias Ceulemans, Jolien Schol, Ricard Farré, Jan Tack & Tim Vanuytsel. (2022) The Role of Leaky Gut in Functional Dyspepsia. Frontiers in Neuroscience 16.
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C. A. M. Wegh, N. M. de Roos, R. Hovenier, J. Meijerink, I. Besseling-van der Vaart, S. van Hemert & B. J. M. Witteman. (2019) Intestinal Permeability Measured by Urinary Sucrose Excretion Correlates with Serum Zonulin and Faecal Calprotectin Concentrations in UC Patients in Remission. Journal of Nutrition and Metabolism 2019, pages 1-10.
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Ying Zhang, Ben Lee, Matthew Thompson, Roger Glass, Rosa Cama Lee, Dante Figueroa, Robert Gilman, David Taylor & Charles Stephenson. (2000) Lactulose–Mannitol Intestinal Permeability Test in Children With Diarrhea Caused by Rotavirus and Cryptosporidium. Journal of Pediatric Gastroenterology and Nutrition 31:1, pages 16-21.
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Renzo Marsilio, Lorenzo D’Antiga, Lucia Zancan, Noemi Dussini & Franco Zacchello. (1998) Simultaneous HPLC determination with light-scattering detection of lactulose and mannitol in studies of intestinal permeability in pediatrics. Clinical Chemistry 44:8, pages 1685-1691.
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E. Duizer, A.H. Penninks, W.H. Stenhuis & J.P. Groten. (1997) Comparison of permeability characteristics of the human colonic Caco-2 and rat small intestinal IEC-18 cell lines. Journal of Controlled Release 49:1, pages 39-49.
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O.A Garden, H.C Rutgers, S.H Sørensen, S Daniels, D Walker & R.M Batt. (1997) Reference range and repeatability of a combined intestinal permeability and function test in clinically healthy Irish setter dogs. Research in Veterinary Science 63:3, pages 257-261.
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I. Bjarnason, A. Macpherson & I. S. Menzies. 1994. Inflammatory Bowel Disease. Inflammatory Bowel Disease 53 70 .

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