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Scandinavian Journal of Gastroenterology Volume 28, 1993 - Issue 7
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Original Article

Intestinal Permeability and Function in Patients Infected with Human Immunodeficiency Virus: A Comparison with Coeliac Disease

S. G. Lim University Dept. of Medicine, Haemophilia Centre, and AIDS Unit, Royal Free Hospital, School of Medicine, London, UK
,
I. S. Menzies University Dept. of Medicine, Haemophilia Centre, and AIDS Unit, Royal Free Hospital, School of Medicine, London, UK
,
C. A. Lee University Dept. of Medicine, Haemophilia Centre, and AIDS Unit, Royal Free Hospital, School of Medicine, London, UK
,
M. A. Johnson University Dept. of Medicine, Haemophilia Centre, and AIDS Unit, Royal Free Hospital, School of Medicine, London, UK
&
R. E. Pounder University Dept. of Medicine, Haemophilia Centre, and AIDS Unit, Royal Free Hospital, School of Medicine, London, UK; Dept. of Chemical Pathology United Medical, Dental Schools, St. Thomas' Hospital, London, UK
Pages 573-580 | Received 14 Oct 1992, Accepted 31 Dec 1992, Published online: 08 Jul 2009

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Ruben Hummelen, Arjan P. Vos, Belinda van’t Land, Klaske van Norren & Gregor Reid. (2010) Altered Host-Microbe Interaction in HIV: A Target for Intervention with Pro- and Prebiotics. International Reviews of Immunology 29:5, pages 485-513.
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Einar Björnsson, Anna Cederborg, Anders Åkvist, Magnus Simren, Per-ove Stotzer & Ingvar Bjarnason. (2005) Intestinal permeability and bacterial growth of the small bowel in patients with primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology 40:9, pages 1090-1094.
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S. M. Riordan, C. J. McIver, D. H. Thomas, V. M. Duncombe, T. D. Bolin & M. C. Thomas. (1997) Luminal Bacteria and Small-Intestinal Permeability. Scandinavian Journal of Gastroenterology 32:6, pages 556-563.
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J. Lysgård Madsen, O. Scharff, A. Rabøl & O. Worm Krogsgaard. (1996) Relationship between Small-Intestinal Transit Rate and Intestinal Absorption of 14C-labelled Mannitol and 51Cr-labelled Ethylenediaminetetraacetic Acid in Healthy Subjects. Scandinavian Journal of Gastroenterology 31:3, pages 254-259.
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Kent D. Taylor, Jerome I. Rotter & Huiying Yang. 2003. Inflammatory Bowel Disease: From Bench to Bedside. Inflammatory Bowel Disease: From Bench to Bedside 21 65 .
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Ronald S Veazey, Preston A Marx & Andrew A Lackner. (2001) The mucosal immune system: primary target for HIV infection and AIDS. Trends in Immunology 22:11, pages 626-633.
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Tamsin A Knox, Donna Spiegelman, Sarah C Skinner & Sherwood Gorbach. (2000) Diarrhea and Abnormalities of Gastrointestinal Function in A Cohort of Men and Women With Hiv Infection. American Journal of Gastroenterology 95:12, pages 3482-3489.
Crossref
YM Miao & BG Gazzard. (2001) Management of protozoal diarrhoea in HIV disease. HIV Medicine 1:4, pages 194-199.
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Stephane Mouly, Guy Aymard, Bertrand Diquet, Charles Caulin & Jean-François Bergmann. (2000) Oral Ganciclovir Systemic Exposure Is Enhanced in HIV-Infected Patients With Diarrhea and Weight Loss. JAIDS Journal of Acquired Immune Deficiency Syndromes 24:4, pages 344-351.
Crossref
Stephane Mouly, Guy Aymard, Bertrand Diquet, Charles Caulin & Jean-François Bergmann. (2000) Oral Ganciclovir Systemic Exposure Is Enhanced in HIV-Infected Patients With Diarrhea and Weight Loss. Journal of Acquired Immune Deficiency Syndromes 24:4, pages 344-351.
Crossref
Lorenzo D'Antiga, Anil Dhawan, Mark Davenport, Giorgina Mieli-Vergani & Ingvar Bjarnason. (1999) Intestinal Absorption and Permeability in Paediatric Short-Bowel Syndrome: A Pilot Study. Journal of Pediatric Gastroenterology and Nutrition 29:5, pages 588-593.
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M. A. Van Nieuwenhoven, B. J. Geerling, N. E. P. Deutz, F. Brouns & R.‐J. M. Brummer. (2003) The sensitivity of the lactulose/rhamnose gut permeability test. European Journal of Clinical Investigation 29:2, pages 160-165.
Crossref
M. Ott & B. Lembcke. 1999. Darmkrankheiten. Darmkrankheiten 337 346 .
Safak Reka & Donald P. Kotler. (1998) Correlation of Intestinal Structure and Function in HIV Infection. Gastrointestinal Endoscopy Clinics of North America 8:4, pages 841-856.
Crossref
O.A. Garden, H.K. Manners, S.H. Sórensen, H.C. Rutgers, S. Daniels, V. Legrand-Defretin & R.M. Batt. (1998) Intestinal permeability of Irish setter puppies challenged with a controlled oral dose of gluten. Research in Veterinary Science 65:1, pages 23-28.
Crossref
Charles M Noyer, Douglas Simon, Alain Borczuk, Lawrence J Brandt, Martin J Lee & Vandana Nehra. (1998) A Double-Blind Placebo-Controlled Pilot Study of Glutamine Therapy for Abnormal Intestinal Permeability in Patients With AIDS. American Journal of Gastroenterology 93:6, pages 972-975.
Crossref
Martin Stockmann, Michael Fromm, Heinz Schmitz, Wolfgang Schmidt, Ernst-Otto Riecken & Jörg-Dieter Schulzke. (1998) Duodenal biopsies of HIV-infected patients with diarrhoea exhibit epithelial barrier defects but no active secretion. AIDS 12:1, pages 43-51.
Crossref
O.A Garden, H.C Rutgers, S.H Sørensen, S Daniels, D Walker & R.M Batt. (1997) Reference range and repeatability of a combined intestinal permeability and function test in clinically healthy Irish setter dogs. Research in Veterinary Science 63:3, pages 257-261.
Crossref
RA Sherwood, JT Marsden, CA Stein, S Somasundaram, C Aitken, JS Oxford, IS Menzies & I Bjarnason. (2016) Intra-Individual Variation in Serum AZT Concentration is Not Related to Intestinal Absorption or Small Intestinal Inflammatory Changes in Human Immunodeficiency Virus-Infected Subjects. Antiviral Chemistry and Chemotherapy 8:4, pages 327-332.
Crossref
C. Mel Wilcox. (1997) Chronic Unexplained Diarrhea in AIDS: Approach to Diagnosis and Management. AIDS Patient Care and STDs 11:1, pages 13-17.
Crossref
C.Mel Wilcox, Linda Rabeneck & Scott Friedman. (1996) AGA technical review: Malnutrition and cachexia, chronic diarrhea, and hepatobiliary disease in patients with human immunodeficiency virus infection. Gastroenterology 111:6, pages 1724-1752.
Crossref
ALAN J. RYAN, RAY-TAI CHANG & CARL V. GISOLFI. (1996) Gastrointestinal permeability following aspirin intake and prolonged running. Medicine &amp Science in Sports &amp Exercise 28:6, pages 698-705.
Crossref
J Keating, I Bjarnason, S Somasundaram, A Macpherson, N Francis, A B Price, D Sharpstone, J Smithson, I S Menzies & B G Gazzard. (1995) Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea.. Gut 37:5, pages 623-629.
Crossref
Adrian Cummins, Geoff Chu, Logan Faust, George Chandy, John Argyrides, Trevor Robb & Peter Wilson. (2016) Malabsorption and Villous Atrophy in Patients Receiving Enteral Feeding. Journal of Parenteral and Enteral Nutrition 19:3, pages 193-198.
Crossref
Ingvar Bjarnason, Andrew Macpherson & Daniel Hollander. (1995) Intestinal permeability: An overview. Gastroenterology 108:5, pages 1566-1581.
Crossref
Rodney E. WilloughbyJrJr & Robert A. Livingston. (1995) Approach to the HIV-infected child with diarrhea. Seminars in Pediatric Infectious Diseases 6:1, pages 17-25.
Crossref
I. Bjarnason, A. Macpherson & I. S. Menzies. 1994. Inflammatory Bowel Disease. Inflammatory Bowel Disease 53 70 .
W. Heise. 1994. Ökosystem Darm VI. Ökosystem Darm VI 3 12 .

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