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Original Article

Mycobacterium paratuberculosis in Intestinal Tissue from Patients with Crohn's Disease Demonstrated by a Nested Primer Polymerase Chain Reaction

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Pages 923-929 | Received 09 Dec 1993, Accepted 11 Feb 1994, Published online: 08 Jul 2009

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Rodrick J. Chiodini, William M. Chamberlin, Jerzy Sarosiek & Richard W. McCallum. (2012) Crohn’s disease and the mycobacterioses: A quarter century later. Causation or simple association?. Critical Reviews in Microbiology 38:1, pages 52-93.
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Ken Over, Philip G. Crandall, Corliss A. O’Bryan & Steven C. Ricke. (2011) Current perspectives on Mycobacterium avium subsp. paratuberculosis, Johne’s disease, and Crohn’s disease: a Review. Critical Reviews in Microbiology 37:2, pages 141-156.
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Sandra Macfarlane, Helen Steed & George T. Macfarlane. (2009) Intestinal bacteria and inflammatory bowel disease. Critical Reviews in Clinical Laboratory Sciences 46:1, pages 25-54.
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Sonia Toracchio, Hala M. T. El-Zimaity, Carlos Urmacher, Seymour Katz & David Y. Graham. (2008) Mycobacterium avium subspecies paratuberculosis and Crohn's disease granulomas. Scandinavian Journal of Gastroenterology 43:9, pages 1108-1111.
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Patricia L Conway. (2001) Prebiotics and human health: The state-of-the-art and future perspectives. Näringsforskning 45:1, pages 13-21.
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Articles from other publishers (59)

Pavan Dhoble, Devendra Desai & Philip Abraham. (2021) Is the rise in Crohn's disease in India accompanied by a fall in intestinal tuberculosis? A single-center experience. Indian Journal of Tuberculosis 68:2, pages 210-214.
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Daniela E. Aust. 2013. Pathologie. Pathologie 571 609 .
Charalambos Kaittanis, Hamza Boukhriss, Santimukul Santra, Saleh A. Naser & J. Manuel Perez. (2012) Rapid and Sensitive Detection of an Intracellular Pathogen in Human Peripheral Leukocytes with Hybridizing Magnetic Relaxation Nanosensors. PLoS ONE 7:4, pages e35326.
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D.A. Qual, J.B. Kaneene, T.J. Varty, R. Miller & C.O. Thoen. (2010) Lack of association between the occurrence of Crohn's disease and occupational exposure to dairy and beef cattle herds infected with Mycobacterium avium subspecies paratuberculosis. Journal of Dairy Science 93:6, pages 2371-2376.
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Jung Mogg Kim. (2010) Inflammatory Bowel Diseases and Enteric Microbiota. The Korean Journal of Gastroenterology 55:1, pages 4.
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Mitnala Sasikala, D. Nageshwar Reddy, Nitesh Pratap, Sanjeev Kumar Sharma, P. Reddy Balkumar, Anuradha Sekaran, Rupa Banerjee & D. Bhaskara Reddy. (2010) Absence of Mycobacterium avium ss paratuberculosis-specific IS900 sequence in intestinal biopsy tissues of Indian patients with Crohn’s disease. Indian Journal of Gastroenterology 28:5, pages 169-174.
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José Ignacio Fortea Ormaechea, Javier P. Gisbert & Ignacio Marín-Jiménez. (2009) Papel de Mycobacterium avium paratuberculosis en la etiopatogenia de la enfermedad de Crohn. Gastroenterología y Hepatología 32:5, pages 353-363.
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M. Griffiths. 2009. Foodborne Pathogens. Foodborne Pathogens 1060 1118 .
Lisa A. Waddell, Andrijana Rajić, Jan Sargeant, Janet Harris, Rocio Amezcua, Lindsay Downey, Susan Read & Scott A. McEwen. (2008) The Zoonotic Potential of Mycobacterium avium spp. paratuberculosis. Canadian Journal of Public Health 99:2, pages 145-155.
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I. Abubakar, D. Myhill, S. H. Aliyu & P. R. Hunter. (2008) Detection of Mycobacterium avium subspecies paratuberculosis from patients with Crohnʼs disease using nucleic acid-based techniques: A systematic review and meta-analysis. Inflammatory Bowel Diseases 14:3, pages 401-410.
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Tanja Kühbacher & Stefan Schreiber. 2008. Capsule Endoscopy. Capsule Endoscopy 91 103 .
Martin Feller, Karin Huwiler, Roger Stephan, Ekkehardt Altpeter, Aijing Shang, Hansjakob Furrer, Gaby E Pfyffer, Thomas Jemmi, Andreas Baumgartner & Matthias Egger. (2007) Mycobacterium avium subspecies paratuberculosis and Crohn's disease: a systematic review and meta-analysis. The Lancet Infectious Diseases 7:9, pages 607-613.
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Saleh A. Naser & Najih A. Naser. 2006. Emerging Infections 7. Emerging Infections 7 225 245 .
M.W. Griffiths. 2006. Emerging Foodborne Pathogens. Emerging Foodborne Pathogens 522 556 .
Joshua R Korzenik. (2005) Past and Current Theories of Etiology of IBD. Journal of Clinical Gastroenterology 39:4, pages S59-S65.
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Claudia Romero, Amal Hamdi, John F. Valentine & Saleh A. Naser. (2005) Evaluation of Surgical Tissue From Patients with Crohnʼs Disease for the Presence of Mycobacterium avium Subspecies paratuberculosis DNA by In Situ Hybridization and Nested Polymerase Chain Reaction. Inflammatory Bowel Diseases 11:2, pages 116-125.
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Fabien K Baksh, Sydney D Finkelstein, Shashi M Ariyanayagam-Baksh, Patricia A Swalsky, Edwin C Klein & Jean C Dunn. (2004) Absence of Mycobacterium avium subsp. paratuberculosis in the microdissected granulomas of Crohn's disease. Modern Pathology 17:10, pages 1289-1294.
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Saleh A Naser, George Ghobrial, Claudia Romero & John F Valentine. (2004) Culture of Mycobacterium avium subspecies paratuberculosis from the blood of patients with Crohn's disease. The Lancet 364:9439, pages 1039-1044.
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K. Hruska. (2004) Research on paratuberculosis: Analysis of publications 1994-2004. Veterinární medicína 49:8, pages 271-282.
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Nackmoon Sung & Michael T. Collins. (2003) Variation in Resistance of Mycobacterium paratuberculosis to Acid Environments as a Function of Culture Medium . Applied and Environmental Microbiology 69:11, pages 6833-6840.
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Murray E. HinesIIII & Eloise L. Styer. (2003) Preliminary characterization of chemically generated Mycobacterium avium subsp. paratuberculosis cell wall deficient forms (Spheroplasts). Veterinary Microbiology 95:4, pages 247-258.
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Robert J Greenstein. (2003) Is Crohn's disease caused by a mycobacterium? Comparisons with leprosy, tuberculosis, and Johne's disease. The Lancet Infectious Diseases 3:8, pages 507-514.
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Jan Wehkamp, Juergen Harder, Michael Weichenthal, Oliver Mueller, Klaus R. Herrlinger, Klaus Fellermann, Jens M. Schroeder & Eduard F. Stange. (2003) Inducible and Constitutive β-Defensins Are Differentially Expressed in Crohn's Disease and Ulcerative Colitis. Inflammatory Bowel Diseases 9:4, pages 215-223.
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Michael Collins. 2003. International Handbook of Foodborne Pathogens. International Handbook of Foodborne Pathogens.
Laura W. Lamps, K. T. Madhusudhan, Jennifer M. Havens, Joel K. Greenson, Mary P. Bronner, Melissa C. Chiles, Patrick J. Dean & Margie A. Scott. (2003) Pathogenic Yersinia DNA Is Detected in Bowel and Mesenteric Lymph Nodes From Patients With Crohn's Disease. The American Journal of Surgical Pathology 27:2, pages 220-227.
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Jan Wehkamp, Klaus Fellermann, Klaus R. Herrlinger, Steffi Baxmann, Klaus Schmidt, Bettina Schwind, Michael Duchrow, Charlotte Wohlschläger, Alfred C. Feller & Eduard F. Stange. (2002) Human β-defensin 2 but not β-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease. European Journal of Gastroenterology & Hepatology 14:7, pages 745-752.
Crossref
Hua Tian Gan, You Qin Chen, Qin Ouyang, Hong Bu & Xiu Ying Yang. (2002) Differentiation between intestinal tuberculosis and Crohn's disease in endoscopic biopsy specimens by polymerase chain reaction. The American Journal of Gastroenterology 97:6, pages 1446-1451.
Crossref
Arlette Darfeuille-Michaud. (2002) Adherent-invasive Escherichia coli: a putative new E. coli pathotype associated with Crohn's disease. International Journal of Medical Microbiology 292:3-4, pages 185-193.
Crossref
T.J. Borody, S. Leis, E.F Warren & R. Surace. (2002) Treatment of severe Crohn's disease using antimycobacterial triple therapy — approaching a cure?. Digestive and Liver Disease 34:1, pages 29-38.
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David W.K. Acheson. (2001) An alternative perspective on the role of Mycobacterium paratuberculosis in the etiology of Crohn's disease. Food Control 12:6, pages 335-338.
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A. Lavy, E. Broide, S. Reif, D. Keter, Y. Niv, S. Odes, R. Eliakim, A. Halak, Y. Ron, J. Patz, A. Fich, Y. Villa, N. Arber & T. Gilat. (2001) Measles is more prevalent in Crohn's disease patients. A multicentre Israeli study. Digestive and Liver Disease 33:6, pages 472-476.
Crossref
S. Englund, G. Bölske, A. Ballagi-Pordány & K.-E. Johansson. (2001) Detection of Mycobacterium avium subsp. paratuberculosis in tissue samples by single, fluorescent and nested PCR based on the IS900 gene. Veterinary Microbiology 81:3, pages 257-271.
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Kristina Hulten, Hala M. T. El-Zimaity, Toumo J. Karttunen, Ashraf Almashhrawi, Mary R. Schwartz, David Y. Graham & Fouad A. K. El-Zaatari. (2001) Detection of Mycobacterium avium Subspecies paratuberculosis in Crohn's Diseased Tissues by In Situ Hybridization. American Journal of Gastroenterology 96:5, pages 1529-1535.
Crossref
W. Chamberlin, D. Y. Graham, K. Hulten, H. M. T. El‐Zimaity, M. R. Schwartz, S. Naser, I. Shafran & F. A. K. El‐Zaatari. (2008) Mycobacterium avium subsp. paratuberculosis as one cause of Crohn’s disease . Alimentary Pharmacology & Therapeutics 15:3, pages 337-346.
Crossref
Michael T. Collins, Gorm Lisby, Claus Moser, Debra Chicks, Steen Christensen, Mark Reichelderfer, Niels Høiby, Bruce A. Harms, Ole Ø. Thomsen, Ulrik Skibsted & Vibeke Binder. (2000) Results of Multiple Diagnostic Tests for Mycobacterium avium subsp. paratuberculosis in Patients with Inflammatory Bowel Disease and in Controls . Journal of Clinical Microbiology 38:12, pages 4373-4381.
Crossref
K Hulten, T.J Karttunen, H.M.T El-Zimaity, S.A Naser, M.T Collins, D.Y Graham & F.A.K El-Zaatari. (2000) Identification of cell wall deficient forms of M. avium subsp. paratuberculosis in paraffin embedded tissues from animals with Johne’s disease by in situ hybridization. Journal of Microbiological Methods 42:2, pages 185-195.
Crossref
Michael J. Page, Lisa S. Poritz, Anna F. Tilberg, Wen Jie Zhang, Michael J. Chorney & Walter A. Koltun. (2000) Cd1d-Restricted Cellular Lysis by Peripheral Blood Lymphocytes: Relevance to the Inflammatory Bowel Diseases. Journal of Surgical Research 92:2, pages 214-221.
Crossref
J.R. Stabel. (2000) Johne's Disease and Milk: Do Consumers Need to Worry?. Journal of Dairy Science 83:7, pages 1659-1663.
Crossref
D. Schwartz, I. Shafran, C. Romero, C. Piromalli, J. Biggerstaff, N. Naser, W. Chamberlin & S.A. Naser. (2000) Use of short-term culture for identification of Mycobacterium avium subsp. paratuberculosis in tissue from Crohn's disease patients. Clinical Microbiology and Infection 6:6, pages 303-307.
Crossref
Nackmoon Sung & Michael T. Collins. (2000) Effect of Three Factors in Cheese Production (pH, Salt, and Heat) on Mycobacterium avium subsp. paratuberculosis Viability . Applied and Environmental Microbiology 66:4, pages 1334-1339.
Crossref
Pietro G. Andres & Lawrence S. Friedman. (1999) EPIDEMIOLOGY AND THE NATURAL COURSE OF INFLAMMATORY BOWEL DISEASE. Gastroenterology Clinics of North America 28:2, pages 255-281.
Crossref
Stina Englund, András Ballagi-Pordány, Göran Bölske & Karl-Erik Johansson. (1999) Single PCR and nested PCR with a mimic molecule for detection of Mycobacterium avium subsp. paratuberculosis. Diagnostic Microbiology and Infectious Disease 33:3, pages 163-171.
Crossref
Irvine S Gottfried, Robert H Nash & Edward W Devlin. (1999) Presence of Novel Forms in the Colon of Inflammatory Bowel Disease Patients. American Journal of Gastroenterology 94:2, pages 537-538.
Crossref
M. Chiba, M. Komatsu, M. Iizuka, O. Masamune, S. Hoshina & M. Kong. (1998) Microbiology of the intestinal lymph follicle: a clue to elucidate causative microbial agent(s) in Crohn's disease. Medical Hypotheses 51:5, pages 421-427.
Crossref
Christophe Coetsier, Xavier Havaux, Francois Mattelard, Sanaa Sadatte, Francoise Cormont, Klaus Buergelt, Bernard Limbourg, Dominique Latinne, Herve Bazin, Jean-Francois Denef & Carlo Cocito. (1998) Detection of Mycobacterium avium subsp. paratuberculosis in Infected Tissues by New Species-Specific Immunohistological Procedures . Clinical Diagnostic Laboratory Immunology 5:4, pages 446-451.
Crossref
I Begara-McGorum, L.A Wildblood, C.J Clarke, K.M Connor, K Stevenson, C.J McInnes, J.M Sharp & D.G Jones. (1998) Early immunopathological events in experimental ovine paratuberculosis. Veterinary Immunology and Immunopathology 63:3, pages 265-287.
Crossref
Nackmoon Sung & Michael T. Collins. (1998) Thermal Tolerance of Mycobacterium paratuberculosis . Applied and Environmental Microbiology 64:3, pages 999-1005.
Crossref
Wendell K. Clarkston, Michael E. Presti, Paul F. Petersen, Paul E. Zachary, W. X. Fan, Craig L. Leonardi, Anthony M. Vernava, Walter E. Longo & John M. Kreeger. (1998) Role of Mycobacterium paratuberculosis in Crohn's disease. Diseases of the Colon & Rectum 41:2, pages 195-199.
Crossref
Bing Xia. (1998) Inflammatory bowel disease: definition, epidemiology, etiologic aspects, and immunogenetic studies. World Journal of Gastroenterology 4:5, pages 446.
Crossref
Michael T. Collins. (1997) Mycobacterium paratuberculosis: A Potential Food-Borne Pathogen?. Journal of Dairy Science 80:12, pages 3445-3448.
Crossref
Janice Miller, Allen Jenny, Jack Rhyan, Dennis Saari & David Suarez. (2016) Detection of Mycobacterium Bovis in Formalin-Fixed, Paraffin-Embedded Tissues of Cattle and Elk by PCR Amplification of an IS6110 Sequence Specific for Mycobacterium Tuberculosis Complex Organisms . Journal of Veterinary Diagnostic Investigation 9:3, pages 244-249.
Crossref
F A El-Zaatari, S A Naser & D Y Graham. (1997) Characterization of a specific Mycobacterium paratuberculosis recombinant clone expressing 35,000-molecular-weight antigen and reactivity with sera from animals with clinical and subclinical Johne's disease. Journal of Clinical Microbiology 35:7, pages 1794-1799.
Crossref
B ZhaoM T CollinsC J Czuprynski. (1997) Effects of gamma interferon and nitric oxide on the interaction of Mycobacterium avium subsp. paratuberculosis with bovine monocytes. Infection and Immunity 65:5, pages 1761-1766.
Crossref
K. Stevenson & J.M. Sharp. (1997) The contribution of molecular biology to Mycobacteriumavium subspecies Paratuberculosis research. The Veterinary Journal 153:3, pages 269-286.
Crossref
C.J. Clarke. (1997) The pathology and pathogenesis of paratuberculosis in ruminants and other species. Journal of Comparative Pathology 116:3, pages 217-261.
Crossref
D MillarJ FordJ SandersonS WitheyM TizardT DoranJ Hermon-Taylor. (1996) IS900 PCR to detect Mycobacterium paratuberculosis in retail supplies of whole pasteurized cows' milk in England and Wales. Applied and Environmental Microbiology 62:9, pages 3446-3452.
Crossref
Jean-Marc Dumonceau, André van Gossum, Michael Adler, Pierre-Alain Fonteyne, Jean-Paul Van Vooren, Jacques Devière & Françoise Portaels. (1996) NoMycobacterium paratuberculosis found in crohn's disease using the polymerase chain reaction. Digestive Diseases and Sciences 41:2, pages 421-426.
Crossref
Guido AdlerGuido Adler. 1996. Morbus Crohn - Colitis ulcerosa. Morbus Crohn - Colitis ulcerosa 321 330 .
F A el-ZaatariS A NaserL EngstrandP E BurchC Y HachemD L WhippleD Y Graham. (1995) Nucleotide sequence analysis and seroreactivities of the 65K heat shock protein from Mycobacterium paratuberculosis. Clinical Diagnostic Laboratory Immunology 2:6, pages 657-664.
Crossref

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