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Scandinavian Journal of Gastroenterology Volume 30, 1995 - Issue 11
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Original Article

Two Dose Regimens of Recombinant Interferon-Alpha-2b in Chronic Hepatitis C Virus Infection: Biochemistry, Hepatitis C Virus RNA, and Liver Histology as Response Indices

K. Bjøro Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
H. Krarup Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
H. Bell Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
P. Christophersen Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
S. Evensen Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
S. S. Frøland Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
A. Laursen Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
B. V.D. Lippe Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
A. Mæland Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
L. Ranek Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
H. Ring-Larsen Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
G. Schou Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
,
E. Schrumpf Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
&
N. Tygstrup Medical Dept. A, Rikshospitalet, Oslo, Norway; Medical Dept., Aker Hospital, Oslo, Norway; Medical Dept., Ullevål Hospital, Oslo, Norway; Medical Dept., Aalborg Hospital, Aalborg, Denmark; Medical Dept., Marselisborg Hospital, Aarhus, Denmark; Dept. of Pathology, Hvidovre Hospital Copenhagen, Copnhangen, Denmark; Medical Dept. A, Rikshospitalet, Copenhagen, Denmark; Division of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
 show all
Pages 1119-1124 | Received 13 May 1994, Accepted 20 Mar 1995, Published online: 08 Jul 2009

Citations (7)

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Helge Bell, Kjell Hellum, Stig Harthug, Arild Mæland, Ståle Ritland, Bjørn Myrvang, Bent Von Der Lippe, Nils Raknerud, Kjell Skaug, Bjørg-Guri Gutigard, Rolv Skjærven, Linda E. Prescott & Peter Simmonds. (1997) Genotype, Viral Load and Age as Independent Predictors of Treatment Outcome of Interferon-α2a Treatment in Patients with Chronic Hepatitis C. Scandinavian Journal of Infectious Diseases 29:1, pages 17-22.
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Articles from other publishers (6)

Fabio Tinè, Massimo Attanasio, Francesca Russo & Luigi Pagliaro. (2005) A decade of trials of interferon-alpha for chronic hepatitis C. A meta-regression analysis. Contemporary Clinical Trials 26:2, pages 179-210.
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Kondili, Taliani, Tosti, De Bac, Pasquazzi & Mele. (2000) Methodological issues in papers on IFN therapy: time for reappraisal. Journal of Viral Hepatitis 7:3, pages 184-195.
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Calogero Cammà, Marco Giunta, Giovanbattista Pinzello, Alberto Morabito, Paolo Verderio & Luigi Pagliaro. (1999) Chronic Hepatitis C and Interferon Alpha: Conventional and Cumulative Meta-Analyses of Randomized Controlled Trials. American Journal of Gastroenterology 94:3, pages 581-595.
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RG BATEYA BENSOUSSANYANG YI FAN, S BOLLIPOMA HOSSAIN. (2009) Preliminary report of a randomized, double‐blind placebo‐controlled trial of a Chinese herbal medicine preparation CH‐100 in the treatment of chronic hepatitis C. Journal of Gastroenterology and Hepatology 13:3, pages 244-247.
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Laursen Scheibel Ingerslev Clausen Wantzin Østergaard Schou Black Krogsgaard. (2002) Alpha interferon therapy in Danish Haemophiliac patients with chronic hepatitis C: results of a randomized controlled open label study comparing two different maintenance regimens following standard interferon‐alpha‐2b treatment. Haemophilia 4:1, pages 25-32.
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Calogero Cammá, Marco Giunta, Cristina Linea & Luigi Pagliaro. (1997) The effect of interferon on the liver in chronic hepatitis C: a quantitative evaluation of histology by meta-analysis. Journal of Hepatology 26:6, pages 1187-1199.
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