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Scandinavian Journal of Gastroenterology Volume 31, 1996 - Issue 8
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Original Article

Attenuation of the Inflammatory Response in an Animal Colitis Model by Neutrophil Inhibitory Factor, a Novel β2-Integrin Antagonist

J. Meenan Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
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D. W. Hommes Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
M. Mevissen Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
S. Dijkhuizen Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
H. Soule Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
M. Moyle Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
H. R. Büller Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
,
F. W. Ten Kate Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
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G. N. J. Tytgat Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands; Corvas International, Inc., San Diego, California, USA
&
S. J. H. Van Deventer Dept. of Gastroenterology and Hepatology; Dept. of Haemostasis, Inflammation, Atherosclerosis and Thrombosis Research (HIAT); and Dept. of Pathology, Academic Medical Centre, Amsterdam, The Netherlands
 show all
Pages 786-791 | Received 10 Jul 1995, Accepted 21 Jan 1996, Published online: 08 Jul 2009

Citations (16)

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T. A. GROOL, H. VAN DULLEMEN, J. MEENAN, F. KOSTER, F. J. W. TEN KATE, A. LEBEAUT, G. N. J. TYTGAT, S. J. H. VAN DEVENTER. (1998) Anti-Inflammatory Effect of Interleukin-10 in Rabbit Immune Complex-Induced Colitis. Scandinavian Journal of Gastroenterology 33:7, pages 754-758.
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Articles from other publishers (15)

Stephanie M. Ryan, Roland Ruscher, Wayne A. Johnston, Darren A. Pickering, Malcolm W. Kennedy, Brian O. Smith, Linda Jones, Geraldine Buitrago, Matt A. Field, Adrian J. Esterman, Connor P. McHugh, Daniel J. Browne, Martha M. Cooper, Rachael Y. M. Ryan, Denise L. Doolan, Christian R. Engwerda, Kim Miles, Makedonka Mitreva, John Croese, Tony Rahman, Kirill Alexandrov, Paul R. Giacomin & Alex Loukas. (2022) Novel antiinflammatory biologics shaped by parasite–host coevolution. Proceedings of the National Academy of Sciences 119:36.
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Julián Panés & Azucena Salas. (2018) Past, Present and Future of Therapeutic Interventions Targeting Leukocyte Trafficking in Inflammatory Bowel Disease. Journal of Crohn's and Colitis 12:suppl_2, pages S633-S640.
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Andreas W. Herling. 2016. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 2415 2467 .
Katja Hattar, Katharina Franz, Michael Ludwig, Ulf Sibelius, Jochen Wilhelm, Jürgen Lohmeyer, Rajkumar Savai, Florentine S. B. Subtil, Gabriele Dahlem, Bastian Eul, Werner Seeger, Friedrich Grimminger & Ulrich Grandel. (2014) Interactions between neutrophils and non-small cell lung cancer cells: enhancement of tumor proliferation and inflammatory mediator synthesis. Cancer Immunology, Immunotherapy 63:12, pages 1297-1306.
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Andreas W. Herling. 2014. Drug Discovery and Evaluation: Pharmacological Assays. Drug Discovery and Evaluation: Pharmacological Assays 1 64 .
Fabrizio Bruschi, Lorena Chiumiento & Gianfranco Del Prete. 2010. Detection of Bacteria, Viruses, Parasites and Fungi. Detection of Bacteria, Viruses, Parasites and Fungi 357 380 .
Jesús Rivera-Nieves, Gezahegn Gorfu & Klaus Ley. (2008) Leukocyte adhesion molecules in animal models of inflammatory bowel disease. Inflammatory Bowel Diseases 14:12, pages 1715-1735.
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Hans Gerhard Vogel. 2008. Drug Discovery and Evaluation. Drug Discovery and Evaluation 1191 1321 .
Sreekant Murthy. 2006. In Vivo Models of Inflammation. In Vivo Models of Inflammation 137 174 .
H. Gerhard Vogel, Wolfgang H. Vogel, Bernward A. Schölkens, Jürgen Sandow, Günter Müller & Wolfgang F. Vogel. 2002. Drug Discovery and Evaluation. Drug Discovery and Evaluation 827 945 .
Klaus Ley & Cartland Burns. (2001) Adhesion molecules in lymphocyte trafficking and colitis. Gastroenterology 121:4, pages 1008-1010.
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Ivan I Pacheco Blandino, Michiro Otaka, Mario Jin, Koga Komatsu, Masaru Odashima, Noriaki Konishi, Toshihiro Sato, Sayuri Kato & Sumio Watanabe. (2002) FR167653, a potent suppressant of interleukin‐1 and tumor necrosis factor‐ α production, ameliorates colonic lesions in experimentally induced acute colitis 1 . Journal of Gastroenterology and Hepatology 16:10, pages 1105-1111.
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Randy E Sacco, David L Hutto, W.Ray Waters, Li Xiasong, Marcus E KehrliJrJr, Federico A Zuckermann & Michael J Wannemuehler. (2000) Reduction in inflammation following blockade of CD18 or CD29 adhesive pathways during the acute phase of a spirochetal-induced colitis in mice. Microbial Pathogenesis 29:5, pages 289-299.
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Julián Panés. (1999) Adhesion molecules in inflammatory bowel disease. Pathophysiology 5:4, pages 271-282.
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Charles N. Bernstein, Michael Sargent & W.Michael Gallatin. (1998) β2 Integrin/ICAM Expression in Crohn's Disease. Clinical Immunology and Immunopathology 86:2, pages 147-160.
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