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Original Article

Gastric Acid Secretion after Depletion of Enterochromaffin-Like Cell Histamine A Study with α-Fluoromethylhistidine in Rats

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Pages 24-30 | Received 07 Apr 1995, Accepted 14 May 1995, Published online: 08 Jul 2009

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Helge L Waldum, Per M Kleveland & Reidar Fossmark. (2015) Upper gastrointestinal physiology and diseases. Scandinavian Journal of Gastroenterology 50:6, pages 649-656.
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Malin Florentzson, Karin Svensson, Maria Astin-Nielsen, Kjell Andersson, Rolf Håkanson & Erik Lindström. (2009) Low gastric acid and high plasma gastrin in high-anxiety Wistar Kyoto rats. Scandinavian Journal of Gastroenterology 44:4, pages 401-407.
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Lennart Friis-Hansen. (2001) Lessons from the gastrin and gastrin receptor knockout mice. Scandinavian Journal of Clinical and Laboratory Investigation 61:234, pages 41-46.
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C.-M. Zhao, D. Chen, H.-J. Monstein, X.-Q. Ding, F. Sundler & R. Håkanson. (1996) Rat Stomach Enterochromaffin-Like Cells Are Not Stimulated by Pylorus Ligation A Biochemical and Ultrastructural Study. Scandinavian Journal of Gastroenterology 31:1, pages 31-37.
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K. Andersson, E. Lindström, D. Chen, H.-J. Monstein, Å. Boketoft & R. Håkanson. (1996) Depletion of Enterochromaffin-Like Cell Histamine Increases Histidine Decarboxylase and Chromogranin: A mRNA Levels in Rat Stomach by a Gastrin-Independent Mechanism. Scandinavian Journal of Gastroenterology 31:10, pages 959-965.
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Erik Lindström, Per Norlén & Rolf Håkanson. (2000) Histamine depletion does not affect pancreastatin secretion from isolated rat stomach ECL cells. European Journal of Pharmacology 387:1, pages 19-25.
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P Norlén, M Kitano, E Lindström & R Håkanson. (2009) Anaesthetic agents inhibit gastrin‐stimulated but not basal histamine release from rat stomach ECL cells. British Journal of Pharmacology 130:4, pages 725-730.
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Masayuki Kitano, Per Norlén, Xi‐Qin Ding, Sanae Nakamura & Rolf Håkanson. (2009) Long‐lasting cholecystokinin 2 receptor blockade after a single subcutaneous injection of YF476 or YM022 . British Journal of Pharmacology 130:3, pages 699-705.
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Bakke, Qvigstad, Brenna, Sandvik & Waldum. (2001) Gastrin has a specific proliferative effect on the rat enterochromaffin‐like cell, but not on the parietal cell: A study by elutriation centrifugation. Acta Physiologica Scandinavica 169:1, pages 29-37.
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M Kitano, P Norlén & R Håkanson. (2000) Gastric submucosal microdialysis: a method to study gastrin- and food-evoked mobilization of ECL-cell histamine in conscious rats. Regulatory Peptides 86:1-3, pages 113-123.
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Per Norlén, Erik Lindström, Xi‐Qin Ding, Masayuki Kitano & Rolf Hákanson. (2009) Reversibility of Cholecystokinin‐B/Gastrin Receptor Blockade: A Study of the Gastrin‐ECL Cell Axis in the Rat. Pharmacology & Toxicology 84:4, pages 159-164.
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Duan Chen, Chun-Mei Zhao, Hironori Yamada, Per Norlén & Rolf Håkanson. (1998) Novel aspects of gastrin-induced activation of histidine decarboxylase in rat stomach ECL cells. Regulatory Peptides 77:1-3, pages 169-175.
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Erik Lindström & Rolf Håkanson. (2009) Prostaglandins inhibit secretion of histamine and pancreastatin from isolated rat stomach ECL cells. British Journal of Pharmacology 124:6, pages 1307-1313.
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Ko Hasebe, Syunji Horie, Shingo Yano & Kazuo Watanabe. (1998) Inhibitory effect of N-nitro-l-arginine on gastric secretion induced by secretagogues and vagal stimulation in the isolated stomach. European Journal of Pharmacology 350:2-3, pages 229-236.
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Xi–Qin Ding, Masayuki Kitano & Rolf Håkanson. (2009) Sustained Cholecystokinin–B/Gastrin Receptor Blockade Does Not Impair Basal or Histamine–Stimulated Acid Secretion in Chronic Gastric Fistula Rats. Pharmacology & Toxicology 82:4, pages 177-182.
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Vikas V Survé & Rolf Håkanson. (1998) Evidence that peroral calcium does not activate the gastrin-ECL-cell axis in the rat. Regulatory Peptides 73:3, pages 177-182.
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Xi‐Qin Ding, Erik Lindström & Rolf Håkanson. (2009) Evaluation of Three Novel Cholecystokinin‐B/Gastrin Receptor Antagonists: A Study of their Effects on Rat Stomach Enterochromaffin‐Like Cell Activity. Pharmacology & Toxicology 81:5, pages 232-237.
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Keizo Kimura, Duan Chen, Erik Lindström, Hironori Yamada, Chun-Mei Zhao & Rolf Håkanson. (1997) Functional impairment of the individual rat stomach ECL cell in response to sustained hypergastrinemia. Regulatory Peptides 72:2-3, pages 69-77.
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X.‐Q. Ding, E. Lindström & R. Håkanson. (2009) Time‐course of deactivation of rat stomach ECL cells following cholecystokinin B /gastrin receptor blockade . British Journal of Pharmacology 122:1, pages 1-6.
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Erik Lindström, Maria Björkqvist, Åke Boketoft, Duan Chen, Chun-Mei Zhao, Keizo Kimura & Rolf Håkanson. (1997) Neurohormonal regulation of histamine and pancreastatin secretion from isolated rat stomach ECL cells. Regulatory Peptides 71:2, pages 73-86.
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Xi‐Qin Ding, Erik Lindström & Rolf Håkanson. (2009) Cholecystokinin‐B/Gastrin Receptor Blockade Suppresses the Activity of Rat Stomach ECL Cells. Pharmacology & Toxicology 81:1, pages 19-25.
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Per Norlén, William J. Curry, Duan Chen, Chun-Mei Zhao, Colin F. Johnston & Rolf Håkanson. (1997) Expression of the chromogranin A-derived peptides pancreastatin and WE14 in rat stomach ECL cells. Regulatory Peptides 70:2-3, pages 121-133.
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D. Chen, C.-M. Zhao, K. Andersson & R. Håkanson. 1997. Biochemical Pharmacology as an Approach to Gastrointestinal Disorders. Biochemical Pharmacology as an Approach to Gastrointestinal Disorders 39 55 .
Xi‐Qin Ding & Rolf Håkanson. (2009) Effect of Cholecystokinin‐B/Gastrin Receptor Blockade on Gastric Acid Secretion in Conscious Rats. Pharmacology & Toxicology 79:6, pages 324-330.
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Duan Chen, Ronald Mårvik, Kirsten Rønning, Kjell Andersson, Helge L. Waldum & Rolf Håkanson. (1996) Gastrin-evoked secretion of pancreastatin and histamine from ECL cells and of acid from parietal cells in isolated, vascularly perfused rat stomach. Effects of isobutyl methylxanthin and α-fluoromethylhistidine. Regulatory Peptides 65:2, pages 133-138.
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