Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 32, 1997 - Issue 2
Submit an article Journal homepage
40
Views
41
CrossRef citations to date
0
Altmetric
Original Article

A Randomized, Double-Blind, Crossover Comparative Endoscopy Study on the Gastroduodenal Tolerability of a Highly Specific Cyclooxygenase-2 Inhibitor, Flosulide, and Naproxen

I. Bjarnason Depts. of Clinical Biochemistry and Medicine, King's College School of Medicine and Dentistry, London, UK; Ciba-Geigy Pharmaceuticals, Basel, Switzerland
,
A. Macpherson Depts. of Clinical Biochemistry and Medicine, King's College School of Medicine and Dentistry, London, UK; Ciba-Geigy Pharmaceuticals, Basel, Switzerland
,
H. Rotman Depts. of Clinical Biochemistry and Medicine, King's College School of Medicine and Dentistry, London, UK; Ciba-Geigy Pharmaceuticals, Basel, Switzerland
,
J. Schupp Depts. of Clinical Biochemistry and Medicine, King's College School of Medicine and Dentistry, London, UK; Ciba-Geigy Pharmaceuticals, Basel, Switzerland
&
J. Hayllar Depts. of Clinical Biochemistry and Medicine, King's College School of Medicine and Dentistry, London, UK; Ciba-Geigy Pharmaceuticals, Basel, Switzerland
Pages 126-130 | Received 12 Aug 1996, Accepted 11 Oct 1996, Published online: 08 Jul 2009

Citations (41)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Frank L Lanza, Agron Collaku & Dongzhou J Liu. (2018) Endoscopic comparison of gastroduodenal injury with over-the-counter doses of new fast-dissolving ibuprofen and paracetamol formulations: a randomized, placebo-controlled, 4-way crossover clinical trial. Clinical and Experimental Gastroenterology 11, pages 169-177.
Read now

Articles from other publishers (40)

Robert G. Lahita & Trina Pal. 2021. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 585 589 .
Robert G. Lahita & Chengqun Shao. 2016. Systemic Lupus Erythematosus. Systemic Lupus Erythematosus 511 514 .
XIAOYU CHEN, JINSENG LU, MEI AN, ZHONGFEI MA, HEXIANG ZONG & JUN YANG. (2014) Anti-inflammatory effect of resveratrol on adjuvant arthritis rats with abnormal immunological function via the reduction of cyclooxygenase-2 and prostaglandin E2. Molecular Medicine Reports 9:6, pages 2592-2598.
Crossref
I. BJARNASON, C. SCARPIGNATO, K. TAKEUCHI & K. D. RAINSFORD. (2007) Determinants of the short-term gastric damage caused by NSAIDs in man. Alimentary Pharmacology & Therapeutics 26:1, pages 95-106.
Crossref
James B. Moberly, Stuart I. Harris, Dennis S. Riff, James Craig Dale, Tara Breese, Patrick McLaughlin, Janet Lawson, Yaping Wan, Jianbo Xu & Kenneth E. Truitt. (2007) A Randomized, Double-Blind, One-Week Study Comparing Effects of a Novel COX-2 Inhibitor and Naproxen on the Gastric Mucosa. Digestive Diseases and Sciences 52:2, pages 442-450.
Crossref
E. Viel, S. Jaber, J. Ripart, F. Navarro & J.-J. Eledjam. (2007) Analgesia postoperatoria nell’adulto (esclusa quella ambulatoriale). EMC - Anestesia-Rianimazione 12:2, pages 1-26.
Crossref
E. Viel, S. Jaber, J. Ripart, F. Navarro & J.-J. Eledjam. (2007) Analgesia postoperatoria en el adulto (excluida la cirugía ambulatoria). EMC - Anestesia-Reanimación 33:2, pages 1-28.
Crossref
E. Viel, S. Jaber, J. Ripart, F. Navarro & J.-J. Eledjam. (2007) Analgésie postopératoire chez l'adulte (ambulatoire exclue). EMC - Anesthésie-Réanimation 4:1, pages 1-26.
Crossref
Monica Valentovic. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 6 .
Laila Abdullah, Ghania Ait-Ghezala, Fiona Crawford, Timothy A. Crowell, Warren W. Barker, Ranjan Duara & Michael Mullan. (2006) The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease. Neuroscience Letters 395:3, pages 240-243.
Crossref
W.David Mauck & Mark-Friedrich B. Hurdle. (2004) Complications of nonopiate pharmacotherapy. Seminars in Pain Medicine 2:4, pages 220-227.
Crossref
Pedro F. Bejarano & Juan F. Herrero. (2003) A Critical Appraisal of COX-2 Selective Inhibition and Analgesia: How Good So Far?. Pain Practice 3:3, pages 201-217.
Crossref
Yasuhiko Ikeda, Kazuo Umemura, Kazunao Kondo, Mitsuyoshi Nakashima, Takuo Kobayashi & Mitsuru Takahashi. (2002) Pharmacokinetics and safety of JTE‐522, a novel selective cyclooxygenase‐2 inhibitor, in healthy male volunteers. British Journal of Clinical Pharmacology 54:5, pages 453-462.
Crossref
Gerard A. Malanga, Steven Roman & Scott F. Nadler. 2002. Whiplash. Whiplash 339 358 .
Friedrich Bottner, Robert Roedl, Klaus Wortler, Claude Grethen, Winfried Winkelmann & Norbert Lindner. (2001) Cyclooxygenase-2 Inhibitor for Pain Management in Osteoid Osteoma. Clinical Orthopaedics and Related Research 393, pages 258-263.
Crossref
Vitaly Gordin, Michael A. Weaver & Marc B. Hahn. (2001) Acute and chronic pain management in palliative care. Best Practice & Research Clinical Obstetrics & Gynaecology 15:2, pages 203-234.
Crossref
Lenard M. Lichtenberger. (2001) Where is the evidence that cyclooxygenase inhibition is the primary cause of nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal injury?. Biochemical Pharmacology 61:6, pages 631-637.
Crossref
KATHLEEN J. SMITH, MARGERUITE GERMAIN & HENRY SKELTON. (2001) Bowenʼs Disease (Squamous Cell Carcinoma In Situ) in Immunosuppressed Patients Treated with Imiquimod 5% Cream and a COX Inhibitor, Sulindac. Dermatologic Surgery 27:2, pages 143-146.
Crossref
Kathleen J. Smith, Margeruite Germain & Henry Skelton. (2001) Bowen's Disease (Squamous Cell Carcinoma In Situ) in Immunosuppressed Patients Treated with Imiquimod 5% Cream and a COX Inhibitor, Sulindac: Potential Applications for This Combination of Immunotherapy. Dermatologic Surgery 27:2, pages 143-146.
Crossref
Koji TAKEUCHI & Akiko TANAKA. (2001) Gastrointestinal sparing anti-inflammatory drugs—COX-2 selective inhibitors and NO-releasing NSAIDs. Folia Pharmacologica Japonica 117:2, pages 138-148.
Crossref
Kenneth M. Verburg, Timothy J. Maziasz, Ethan Weiner, Leland Loose, G. Steven Geis & Peter C. Isakson. (2001) COX-2???Specific Inhibitors: Definition of a New Therapeutic Concept. American Journal of Therapeutics 8:1, pages 49-64.
Crossref
Alan S. Nies & Michael J. Gresser. 2001. Drug Discovery and Design. Drug Discovery and Design 115 141 .
Angela Northey, Danielle Denis, Maria Cirino, Kathleen M. Metters & François Nantel. (2000) Cellular distribution of prostanoid EP receptors mRNA in the rat gastrointestinal tract. Prostaglandins & Other Lipid Mediators 62:2, pages 145-156.
Crossref
Mark FeldmanAlexander T. McMahon. (2000) Do Cyclooxygenase-2 Inhibitors Provide Benefits Similar to Those of Traditional Nonsteroidal Anti-Inflammatory Drugs, with Less Gastrointestinal Toxicity?. Annals of Internal Medicine 132:2, pages 134.
Crossref
M. Cuendet & M. Pezzuto. (2000) The Role of Cyclooxygenase and Lipoxygenase in Cancer Chemoprevention. Drug Metabolism and Drug Interactions 17:1-4.
Crossref
David B. Fournier & Gary B. Gordon. (2000) COX-2 and colon cancer: Potential targets for chemoprevention. Journal of Cellular Biochemistry 77:S34, pages 97-102.
Crossref
Gerard A. Malanga & Scott F. Nadler. (1999) Nonoperative Treatment of Low Back Pain. Mayo Clinic Proceedings 74:11, pages 1135-1148.
Crossref
Byron Cryer. (1999) Nonsteroidal anti-inflammatory drug gastrointestinal toxicity. Current Opinion in Gastroenterology 15:6, pages 473.
Crossref
Pedro F. Bejarano. (1999) Management of inflammatory pain with selective COX-2 inhibitors: Promises and facts. Current Review of Pain 3:6, pages 432-439.
Crossref
Schoenfeld, Kimmey, Scheiman, Bjorkman & Laine. (2001) Review article: nonsteroidal anti‐inflammatory drug‐associated gastrointestinal complications—guidelines for prevention and treatment. Alimentary Pharmacology & Therapeutics 13:10, pages 1273-1285.
Crossref
François Nantel, Danielle Denis, Robert Gordon, Angela Northey, Maria Cirino, Kathleen M Metters & Chi Chung Chan. (2009) Distribution and regulation of cyclooxygenase‐2 in carrageenan‐induced inflammation. British Journal of Pharmacology 128:4, pages 853-859.
Crossref
A. A. Shah, D. J. Fitzgerald & F. E. Murray. (1999) Non-steroidal anti-inflammatory drugs (NSAIDs) and gastro-intestinal toxicity: Current issues. Irish Journal of Medical Science 168:4, pages 242-245.
Crossref
François Nantel, Emily Meadows, Danielle Denis, Brett Connolly, Kathleen M. Metters & Adel Giaid. (1999) Immunolocalization of cyclooxygenase-2 in the macula densa of human elderly. FEBS Letters 457:3, pages 475-477.
Crossref
Bhupinderjit S Anand, Jim J Romero, Sudershan K Sanduja & Lenard M Lichtenberger. (1999) Phospholipid Association Reduces The Gastric Mucosal Toxicity of Aspirin in Human Subjects. American Journal of Gastroenterology 94:7, pages 1818-1822.
Crossref
M. Michael Wolfe, David R. Lichtenstein & Gurkirpal Singh. (1999) Gastrointestinal Toxicity of Nonsteroidal Antiinflammatory Drugs. New England Journal of Medicine 340:24, pages 1888-1899.
Crossref
Jean-Pierre Pelletier, Denis Choquette, Boulos Haraoui, Jean-Pierre Raynauld, Éric Rich, Julio C. Fernandes & Johanne Martel-Pelletier. (1999) Pharmacologic therapy of osteoarthritis. Current Rheumatology Reports 1:1, pages 54-58.
Crossref
J.-Y. Reginster, J.-P. Pelletier, J. Martel-Pelletier, Y. Henrotin & L. CrasbornJ. P. Pelletier, B. Haraoui & J. C. Fernandes. 1999. Osteoarthritis. Osteoarthritis 387 408 .
Michel Pairet, Joanne van Ryn & Manuel Distel. 1999. Inducible Enzymes in the Inflammatory Response. Inducible Enzymes in the Inflammatory Response 1 30 .
Neville D. Yeomans, Gregory A. Cook & Andrew S. Giraud. (1998) Selective COX-2 inhibitors: Are they safe for the stomach?. Gastroenterology 115:1, pages 227-229.
Crossref
A. Del Favero. 1998. 95 114 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.