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Original Article

Ceftriaxone: Pharmacokinetics and Effect on the Intestinal Microflora in Patients with Acute Bacterial Infections

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Pages 77-82 | Published online: 08 Jul 2009

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Read on this site (5)

Fatemeh Rafii, John B Sutherland & Carl E Cerniglia. (2008) Effects of treatment with antimicrobial agents on the human colonic microflora. Therapeutics and Clinical Risk Management 4:6, pages 1343-1358.
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C. E. Nord & C. Edlund. (1991) Ecological Effects of Antimicrobial Agents on the Human Intestinal Microflora. Microbial Ecology in Health and Disease 4:4, pages 193-207.
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Hilly G. De Vries-Hospers, Rudi H. J. Tonk & Dirk Van Der Waaij. (1991) Effect of intramuscular ceftriaxone on aerobic oral and faecal flora of 11 healthy volunteers. Scandinavian Journal of Infectious Diseases 23:5, pages 625-633.
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C.E. Nord & C. Edlund. (1990) Impact of Antimicrobial Agents on Human Intestinal Microflora. Journal of Chemotherapy 2:4, pages 218-237.
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Tom Bergan, Bertil Ekströn & Carl Erik Nord. (1986) Ecological Impacts of Antibacterial Agents: Stockholm, March 7–8, 1986. Scandinavian Journal of Infectious Diseases 18:sup49, pages 1-203.
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Articles from other publishers (17)

C A Hobson, L Vigue, S Naimi, B Chassaing, M Magnan, S Bonacorsi, B Gachet, I El Meouche, A Birgy & O Tenaillon. (2022) MiniBioReactor Array (MBRA) in vitro gut model: a reliable system to study microbiota-dependent response to antibiotic treatment . JAC-Antimicrobial Resistance 4:4.
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Nagisa Godefroy, Helga Junot, Laurence Drieux-Rouzet, Cyril Méloni, Charles-Edouard Luyt, Jérôme Robert & Alexandre Bleibtreu. (2021) Clostridioides difficile Infection Rates after Ceftolozane–Tazobactam and Ceftazidime–Avibactam Treatment Compared to Carbapenem Treatment: A Retrospective Single-Center Study. Hygiene 1:3, pages 99-105.
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Hasinika K. A. H. Gamage, Carola Venturini, Sasha G. Tetu, Masrura Kabir, Vineet Nayyar, Andrew N. Ginn, Belinda Roychoudhry, Lee Thomas, Mitchell Brown, Andrew Holmes, Sally R. Partridge, Ian Seppelt, Ian T. Paulsen & Jonathan R. Iredell. (2021) Third generation cephalosporins and piperacillin/tazobactam have distinct impacts on the microbiota of critically ill patients. Scientific Reports 11:1.
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Petra Zimmermann & Nigel Curtis. (2019) The effect of antibiotics on the composition of the intestinal microbiota - a systematic review. Journal of Infection 79:6, pages 471-489.
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Amira A Bhalodi, Tjitske S R van Engelen, Harjeet S Virk & W Joost Wiersinga. (2019) Impact of antimicrobial therapy on the gut microbiome. Journal of Antimicrobial Chemotherapy 74:Supplement_1, pages i6-i15.
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Philip Toltzis, Michael Dul, Mary Ann O'Riordan, Hasida Toltzis & Jeffrey L. Blumer. (2007) Comparative Effects of Single-Dose Ceftriaxone Versus Three Oral Antibiotic Regimens on Stool Colonization by Resistant Bacilli in Children. Pediatric Infectious Disease Journal 26:1, pages 25-30.
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Åsa Sullivan & Carl Nord. 2006. Gastrointestinal Microbiology. Gastrointestinal Microbiology 335 369 .
Åsa Sullivan, Charlotta Edlund & Carl Erik Nord. 2005. Antimicrobial Agents. Antimicrobial Agents 1357 1370 .
Harriet M. Lamb, Douglas Ormrod, Lesley J. Scott & David P. Figgitt. (2002) Ceftriaxone. Drugs 62:7, pages 1041-1089.
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F. Vogel, H.R. Ochs, K. Wettich, S. Kaiich, I. Nihson-Ehle, I. Odenholt & C.E. Nord. (2001) Effect of step-down therapy of ceftriaxone plus loracarbef versus parenteral therapy of ceftriaxone on the intestinal microflora in patients with community-acquired pneumonia. Clinical Microbiology and Infection 7:7, pages 376-379.
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John Manzella, Ronald Benenson, Gene Pellerin, James Kellogg, Theodore Bell, Michelle Robertson & Doris Pope. (2015) Choice of Antibiotic and Risk of Colonization With Vancomycin-Resistant Enterococcus Among Patients Admitted for Treatment of Community-Acquired Pneumonia . Infection Control & Hospital Epidemiology 21:12, pages 789-791.
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Subhani, Kibbler & Dooley. (1999) Review article: antibiotic prophylaxis for endoscopic retrograde cholangiopancreatography (ERCP). Alimentary Pharmacology & Therapeutics 13:2, pages 103-116.
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Burt R. Meyers, Patricia Wilkinson, Meryl H. Mendelson, Cynthia Bournazos, Carmelita Tejero & Shalom Z. Hirschman. (2013) Pharmacokinetics of Aztreonam in Healthy Elderly and Young Adult Volunteers. The Journal of Clinical Pharmacology 33:5, pages 470-474.
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G. W. Welling, Geke J. Meijer-Severs, Gé Helmus, Edith van Santen, R. H. J. Tonk, Hilly G. de Vries- Hospers & D. van der Waaij. (1991) The effect of ceftriaxone on the anaerobic bacterial flora and the bacterial enzymatic activity in the intestinal tractEinfluß von Ceftriaxon auf die anaerobe Flora und die bakterielle Enzymaktivität im Intestinaltrakt. Infection 19:5, pages 313-316.
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Thomas T. Yoshikawa. (1990) Antimicrobial Therapy for the Elderly Patient. Journal of the American Geriatrics Society 38:12, pages 1353-1372.
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Carl Erik Nord. 1989. Anaerobic Infections in Humans. Anaerobic Infections in Humans 55 80 .
A. Rastegar Lari, J.C. Borderon, F. Gold & J. Laugier. (1989) Administration précoce d'une souche de Escherichia coli antibiosensible dans l'intestin du nouveau-né prématuré. Research in Microbiology 140:1, pages 69-73.
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