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Xenobiotica
the fate of foreign compounds in biological systems
Volume 40, 2010 - Issue 8
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Animal Pharmacokinetics and Metabolism

Pharmacokinetic/pharmacodynamic (PK/PD) differentiation of native and PEGylated recombinant human growth hormone (rhGH and PEG-rhGH) in the rat model of osteoarthritis

Olga NemirovskiyPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USACorrespondence[email protected]
,
Yi J. ZhengPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
David TungPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
Brian KorniskiPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
Steve SettlePfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
Adam SkepnerPfizer Global Research and Development, Groton, CT, USA
,
Matthew YatesPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
Poonam AggarwalPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
,
Teresa SunyerPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
&
Dean J. AguiarPfizer Global Research and Development, St. Louis Laboratories, St. Louis, MO, USA
 show all
Pages 586-592 | Received 12 Feb 2010, Accepted 21 Apr 2010, Published online: 28 May 2010

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Jie Liu, Huarong Shao, Shaoying Fang, Yanling Cheng, Peixue Ling & Jianying Chen. (2019) Evaluation of pharmacokinetics and pharmaco­dynamics of sinomenine­hyaluronic acid conjugate after intra­articular administration for osteoarthritis treatment. Drug Design, Development and Therapy 13, pages 657-665.
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Articles from other publishers (10)

Soo-Min Ok, Jin-Hwa Kim, Ji-Su Kim, Eun-gyo Jeong, Yang Mi Park, Hye-Mi Jeon, Jun-Young Heo, Yong-Woo Ahn, Sun-Nyoung Yu, Hae Ryoun Park, Kyung-Hee Kim, Soon-Cheol Ahn & Sung-Hee Jeong. (2020) Local Injection of Growth Hormone for Temporomandibular Joint Osteoarthritis. Yonsei Medical Journal 61:4, pages 331.
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Thanh N. Doan, Fabrice C. Bernard, Jay M. McKinney, J. Brandon Dixon & Nick J. Willett. (2019) Endothelin-1 inhibits size dependent lymphatic clearance of PEG-based conjugates after intra-articular injection into the rat knee. Acta Biomaterialia 93, pages 270-281.
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Bin Liu, Danping Fan, Wen Sun, Kang Zheng, Guoming Pang, Xiaojuan He, Cheng Xiao & Cheng Lu. (2018) Zhuang Gu Guan Jie Wan: Reasonable Application Can Alleviate the Liver Injury for Osteoarthritis Treatment. Evidence-Based Complementary and Alternative Medicine 2018, pages 1-10.
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Natalie R. Danna, Bryan G. Beutel, Austin J. Ramme, Thorsten Kirsch, Oran D. Kennedy & Eric Strauss. (2016) The Effect of Growth Hormone on Chondral Defect Repair. CARTILAGE 9:1, pages 63-70.
Crossref
Frank P. Luyten, Cosimo De Bari & Francesco Dell'Accio. 2017. Kelley and Firestein's Textbook of Rheumatology. Kelley and Firestein's Textbook of Rheumatology 90 105.e4 .
Poupak Rahimzadeh, Farnad Imani, Seyed-Hamid-Reza Faiz, Mahmoud-Reza Alebouyeh, Damoon Azad-Ehyaei, Leila Bahari, Arash Memarian & Kyung-Hoon Kim. (2016) Adding Intra-Articular Growth Hormone to Platelet Rich Plasma under Ultrasound Guidance in Knee Osteoarthritis: A Comparative Double-Blind Clinical Trial. Anesthesiology and Pain Medicine 6:6.
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Moorthy S.S. Palanki, Abhijit Bhat, Ben Bolanos, Florence Brunel, Joselyn Del Rosario, Danielle Dettling, Mark Horn, Rodney Lappe, Ryan Preston, Annette Sievers, Nebojsa Stankovic, Gary Woodnut & Gang Chen. (2013) Development of a long acting human growth hormone analog suitable for once a week dosing. Bioorganic & Medicinal Chemistry Letters 23:2, pages 402-406.
Crossref
Frank P. Luyten. 2013. Kelley's Textbook of Rheumatology. Kelley's Textbook of Rheumatology 90 96 .
Yulia Vugmeyster, Qin Wang, Xin Xu, John Harrold, Daren Daugusta, Jian Li, Richard Zollner, Carl R. Flannery & Moisés A. Rivera-Bermúdez. (2012) Disposition of Human Recombinant Lubricin in Naive Rats and in a Rat Model of Post-traumatic Arthritis After Intra-articular or Intravenous Administration. The AAPS Journal 14:1, pages 97-104.
Crossref
Laith M Jazrawi & Ankit Bansal. (2012) Biochemical-based MRI in diagnosis of early osteoarthritis. Imaging in Medicine 4:1, pages 1-3.
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