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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 1
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General Xenobiochemistry

3-Methoxylphenylpropyl amides as novel receptor subtype-selective melatoninergic ligands: characterization of physicochemical and pharmacokinetic properties

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Pages 35-45 | Received 04 Aug 2010, Accepted 13 Sep 2010, Published online: 26 Nov 2010

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Jing Zhu, Yueqing Hu, Maurice K. C Ho & Yung H. Wong. (2012) Pharmacokinetics, oral bioavailability and metabolism of a novel isoquinolinone-based melatonin receptor agonist in rats. Xenobiotica 42:11, pages 1138-1150.
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Andrew Tsotinis, Pandelis A. Afroudakis, Ioannis P. Papanastasiou, Aikaterini Sakellaropoulou, Marina Boniakou, Dimitri Komiotis, Peter J. Garratt, Philippe Delagrange, Alina Bocianowska‐Zbrog & David Sugden. (2022) Mapping the Melatonin Receptor. 8. Selective MT2 Agonists Derived from 5,6‐Dihydroindolo[2,1‐ a ]isoquinolines and Related Systems . ChemMedChem 17:12.
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Marcos Antonio FerreiraJr.Jr., Hatylas Azevedo, Alessandra Mascarello, Natanael Dante Segretti, Elisa Russo, Valter Russo & Cristiano Ruch Werneck Guimarães. (2021) Discovery of ACH-000143 : A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats . Journal of Medicinal Chemistry 64:4, pages 1904-1929.
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Andrew Tsotinis, Rodanthi Kompogennitaki, Ioannis Papanastasiou, Peter J. Garratt, Alina Bocianowska & David Sugden. (2019) Fluorine substituted methoxyphenylalkyl amides as potent melatonin receptor agonists. MedChemComm 10:3, pages 460-464.
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Alessandro Pedretti, Angelica Mazzolari, Giulio Vistoli & Bernard Testa. (2018) MetaQSAR: An Integrated Database Engine to Manage and Analyze Metabolic Data. Journal of Medicinal Chemistry 61:3, pages 1019-1030.
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Andrew Tsotinis, Pandelis A. Afroudakis, Peter J. Garratt, Alina Bocianowska-Zbrog & David Sugden. (2014) Benzocyclobutane, Benzocycloheptane and Heptene Derivatives as Melatonin Agonists and Antagonists. ChemMedChem 9:10, pages 2238-2243.
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Zeliha Hayvalı, Hüseyin Güler, Hatice Öğütcü & Nurşen Sarı. (2014) Novel bis-crown ethers and their sodium complexes as antimicrobial agent: synthesis and spectroscopic characterizations. Medicinal Chemistry Research 23:8, pages 3652-3661.
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Yueqing Hu, Jing Zhu, King H. Chan & Yung H. Wong. (2013) Development of substituted N-[3-(3-methoxylphenyl)propyl] amides as MT2-selective melatonin agonists: Improving metabolic stability. Bioorganic & Medicinal Chemistry 21:2, pages 547-552.
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Catherine C.K. Wong & Yung Hou Wong. 2013. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds. Antitumor Potential and other Emerging Medicinal Properties of Natural Compounds 387 404 .

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