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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 6
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Pharmacogenetics

Effects of CYP2C19 polymorphism on the pharmacokinetics of lansoprazole and its main metabolites in healthy Chinese subjects

Dan ZhangDepartment of Clinical Pharmacology, Aerospace Center Hospital, Beijing, P.R. China
,
Xiaolin WangDepartment of Clinical Pharmacology, Aerospace Center Hospital, Beijing, P.R. China
,
Man YangDepartment of Clinical Pharmacology, Aerospace Center Hospital, Beijing, P.R. China
,
Guocai WangDepartment of Clinical Pharmacology, Aerospace Center Hospital, Beijing, P.R. China
&
Huichen LiuDepartment of Clinical Pharmacology, Aerospace Center Hospital, Beijing, P.R. ChinaCorrespondence[email protected]
Pages 511-517 | Received 15 Nov 2010, Accepted 28 Jan 2011, Published online: 27 Apr 2011

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Dan Zhang, Man Yang, Man Liu, Yanan Zhang, Xiaolin Wang, Xue Xiao & Huichen Liu. (2012) Pharmacokinetics of lansoprazole and its main metabolites after single intravenous doses in healthy Chinese subjects. Xenobiotica 42:11, pages 1156-1162.
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Articles from other publishers (8)

Caroline Sychterz, Iain Gardner, Manting Chiang, Ramakrishna Rachumallu, Sibylle Neuhoff, Vidya Perera, Samira Merali, Brian J. Schmidt & Lu Gaohua. (2022) Performance Verification of CYP2C19 Enzyme Abundance Polymorphism Settings within the Simcyp Simulator v21. Metabolites 12:10, pages 1001.
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He-Jian Zhang, Xue-Hui Zhang, Jie Liu, Lu-Ning Sun, Yi-Wen Shen, Chen Zhou, Hong-Wen Zhang, Li-Jun Xie, Juan Chen, Yun Liu & Yong-Qing Wang. (2020) Effects of genetic polymorphisms on the pharmacokinetics and pharmacodynamics of proton pump inhibitors. Pharmacological Research 152, pages 104606.
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Katarína Kostolanská, Ondřej Peš, Ondřej Zendulka, Jan Máchal & Jan Juřica. (2019) Determination of lansoprazole, 5-hydroxylansoprazole, and lansoprazole sulfone in human plasma for CYP2C19 and CYP3A4 phenotyping. Chemical Papers 73:12, pages 2955-2963.
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Li Zhou, Pradeep Sharma, Karen Rowland Yeo, Mitsuo Higashimori, Hongmei Xu, Nidal Al-Huniti & Diansong Zhou. (2019) Assessing pharmacokinetic differences in Caucasian and East Asian (Japanese, Chinese and Korean) populations driven by CYP2C19 polymorphism using physiologically-based pharmacokinetic modelling. European Journal of Pharmaceutical Sciences 139, pages 105061.
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Sijie Lu, R. A. Nand, J. S. Yang, Gang Chen & A. S. Gross. (2017) Pharmacokinetics of CYP2C9, CYP2C19, and CYP2D6 substrates in healthy Chinese and European subjects. European Journal of Clinical Pharmacology 74:3, pages 285-296.
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John J Lima & James P Franciosi. (2014) Pharmacogenomic testing: the case for CYP2C19 proton pump inhibitor gene–drug pairs . Pharmacogenomics 15:11, pages 1405-1416.
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Chang-Yin Li, Jun Zhang, Ji-Hong Chu, Mei-Juan Xu, Wen-Zheng Ju, Fang Liu & Jian-Dong Zou. (2013) A correlative study of polymorphisms of CYP2C19 and MDR1 C3435T with the pharmacokinetic profiles of lansoprazole and its main metabolites following single oral administration in healthy adult Chinese subjects. European Journal of Drug Metabolism and Pharmacokinetics 39:2, pages 121-128.
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Dan Zhang, Yanan Zhang, Man Liu, Xiaolin Wang, Man Yang, Jing Han & Huichen Liu. (2012) Pharmacokinetics of lansoprazole and its main metabolites after single and multiple intravenous doses in healthy Chinese subjects. European Journal of Drug Metabolism and Pharmacokinetics 38:3, pages 209-215.
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