Advanced search
Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 7
Submit an article Journal homepage
449
Views
12
CrossRef citations to date
0
Altmetric
General Xenobiochemistry

In vitro stability and metabolism of O2′, O3′, O5′-tri-acetyl-N6-(3-hydroxylaniline) adenosine in rat, dog and human plasma: Chemical hydrolysis and role of plasma esterases

Yin LiuKey Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine affiliated to Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
,
Jiuming HeKey Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine affiliated to Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
,
Zeper AblizKey Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine affiliated to Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China
&
Haibo ZhuKey Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine affiliated to Ministry of Education, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, ChinaCorrespondence[email protected] [email protected]
Pages 549-560 | Received 18 Dec 2010, Accepted 15 Mar 2011, Published online: 13 Apr 2011

Citations (12)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Feng Gao, Yue-Jiao Qian, Fei-Hu Chen & Hai-Bo Zhu. (2019) Comparative analysis of stimulation and binding characteristics of adenosine analogs to AMP-activated protein kinase. Journal of Asian Natural Products Research 21:9, pages 916-927.
Read now

Articles from other publishers (11)

Artem D. Rogachev, Valentina P. Putilova, Anna V. Zaykovskaya, Olga I. Yarovaya, Anastasiya S. Sokolova, Vladislav V. Fomenko, Oleg V. Pyankov, Rinat A. Maksyutov, Andrey G. Pokrovsky & Nariman F. Salakhutdinov. (2021) Biostability study, quantitation method and preliminary pharmacokinetics of a new antifilovirus agent based on borneol and 3-(piperidin-1-yl)propanoic acid. Journal of Pharmaceutical and Biomedical Analysis 199, pages 114062.
Crossref
Pahweenvaj Ratnatilaka Na Bhuket, Ponsiree Jithavech, Boonsri Ongpipattanakul & Pornchai Rojsitthisak. (2019) Interspecies differences in stability kinetics and plasma esterases involved in hydrolytic activation of curcumin diethyl disuccinate, a prodrug of curcumin. RSC Advances 9:8, pages 4626-4634.
Crossref
Mengxia Jin, Na Guo, Tianqi Li, Xia Liu, Shanshan Sun, Xiangju Jin, Haibo Zhu, Hailin Qin & Yinghong Wang. (2018) Comprehensive characterization of in vitro and in vivo metabolites of 2′,3′,5′‑tri‑O‑acetyl‑N6‑(3‑hydroxyphenyl) adenosine and study of the metabolites distribution in rats by combined methods of HPLC-DAD, off-line cryoNMR, and HPLC-QTOFMS. Journal of Chromatography B 1096, pages 187-200.
Crossref
Toshihiro Hamajima, Fumie Takahashi, Koji Kato, Koichiro Mukoyoshi, Kousei Yoshihara, Susumu Yamaki, Yukihito Sugano, Ayako Moritomo, Kaoru Yamagami, Koji Yokoo & Hidehiko Fukahori. (2018) Discovery and biological evaluation of novel pyrazolopyridine derivatives as potent and orally available PI3Kδ inhibitors. Bioorganic & Medicinal Chemistry 26:9, pages 2410-2419.
Crossref
Jin Li, Bo Chen, Liping Zhong, Feng Gao, Haibo Zhu & Fengzhong Wang. (2018) AMP-activated protein kinase agonist N6-(3-hydroxyphenyl)adenosine protects against fulminant hepatitis by suppressing inflammation and apoptosis. Cell Death & Disease 9:2.
Crossref
Pahweenvaj Ratnatilaka Na Bhuket, Nuansri Niwattisaiwong, Patanachai Limpikirati, Phisit Khemawoot, Pasarapa Towiwat, Boonsri Ongpipattanakul & Pornchai Rojsitthisak. (2016) Simultaneous determination of curcumin diethyl disuccinate and its active metabolite curcumin in rat plasma by LC–MS/MS: Application of esterase inhibitors in the stabilization of an ester-containing prodrug. Journal of Chromatography B 1033-1034, pages 301-310.
Crossref
Wen-Xuan Zhang, Hong-Na Wu, Bo Li, Hong-Lin Wu, Dong-Mei Wang & Song Wu. (2015) The Synthesis of the Metabolites of 2′,3′,5′-Tri-O-acetyl-N6-(3-hydroxyphenyl) Adenosine (WS070117). Molecules 21:1, pages 8.
Crossref
Xiaolin Wang, Xiao Gu, Huahua Song, Qingxiang Song, Xiaoling Gao, Yang Lu & Hongzhuan Chen. (2015) Phenylmethanesulfonyl fluoride pretreatment stabilizes plasma lipidome in lipidomic and metabolomic analysis. Analytica Chimica Acta 893, pages 77-83.
Crossref
Wei Guo, Mengxia Jin, Zhaoxia Miao, Kai Qu, Xia Liu, Peicheng Zhang, Hailin Qin, Haibo Zhu & Yinghong Wang. (2015) Structure Elucidation of the Metabolites of 2', 3', 5'-Tri-O-Acetyl-N6-(3-Hydroxyphenyl) Adenosine in Rat Urine by HPLC-DAD, ESI-MS and Off-Line Microprobe NMR. PLOS ONE 10:6, pages e0127583.
Crossref
Zhixia Qiu, Ning Li, Ling Song, Yang Lu, Jing Jing, Harendra S. Parekha, Wenchao Gao, Fengjie Tian, Xin Wang, Shuangxia Ren & Xijing Chen. (2013) Contributions of Intestine and Plasma to the Presystemic Bioconversion of Vicagrel, an Acetate of Clopidogrel. Pharmaceutical Research 31:1, pages 238-251.
Crossref
Feng You, Jinping Hu, Xue Li & Yan Li. (2013) The elimination of MTC-220, a novel anti-tumor agent of conjugate of paclitaxel and muramyl dipeptide analogue, in rats. Cancer Chemotherapy and Pharmacology 71:6, pages 1453-1462.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.