Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 10
359
Views
24
CrossRef citations to date
0
Altmetric
Animal Pharmacokinetics and Metabolism

Pharmacokinetic characterization of decursinol derived from Angelica gigas Nakai in rats

, , , , , , & show all
Pages 895-902 | Received 30 Mar 2011, Accepted 09 May 2011, Published online: 09 Jun 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

In-Hwan Baek, Byung-Yo Lee, Jung-Woo Chae, Gyu Yong Song, Wonku Kang & Kwang-Il Kwon. (2014) Development of a pharmacokinetic/pharmacodynamic/disease progression model in NC/Nga mice for development of novel anti-atopic dermatitis drugs. Xenobiotica 44:11, pages 975-987.
Read now
Bimit Mahat, Jung-woo Chae, In-hwan Baek, Gyu-yong Song, Jin-sook Song, Jin-yeul Ma & Kwang-il Kwon. (2013) Biopharmaceutical characterization of decursin and their derivatives for drug discovery. Drug Development and Industrial Pharmacy 39:10, pages 1523-1530.
Read now
Kyeong-Ryoon Lee, Sung Heum Choi, Jin-Sook Song, Eun-Young Kwak, Yoon-Jee Chae, So Hee Im, Byung Hoi Lee, Hyewon Seo, Woon-Ki Cho, Min-Sun Kim, Nak Jeong Kim, Sung-Hoon Ahn & Myung Ae Bae. (2013) Pharmacokinetic characterization of the novel TAZ modulator TM-25659 using a multicompartment kinetic model in rats and a possibility of its drug–drug interactions in humans. Xenobiotica 43:2, pages 193-200.
Read now

Articles from other publishers (21)

Xuanming Zhao, Jing Di, Dingjie Luo, Yogesh Vaishnav, Kamal, Nargiza Nuralieva, Deepti Verma, Payal Verma & Shekhar Verma. (2024) Recent developments of P-glycoprotein inhibitors and its structure–activity relationship (SAR) studies. Bioorganic Chemistry 143, pages 106997.
Crossref
Zilong He, Yudi Wang, Yonghu Chen, Feifei Geng, Zhe Jiang & Xuezheng Li. (2023) Angelica gigas Nakai: An overview on its chemical composition and pharmacological activity. Biochemical Systematics and Ecology 111, pages 104717.
Crossref
Junxuan Lü, Cheng Jiang, Todd D. Schell, Monika Joshi, Jay D. Raman & Chengguo Xing. (2022) Angelica gigas : Signature Compounds, In Vivo Anticancer, Analgesic, Neuroprotective and Other Activities, and the Clinical Translation Challenges . The American Journal of Chinese Medicine 50:06, pages 1475-1527.
Crossref
Sook-Jin Kim, Se-Mi Ko, Eun-Jeong Choi, Seong-Ho Ham, Young-Dal Kwon, Yong-Bok Lee & Hea-Young Cho. (2018) Simultaneous Determination of Decursin, Decursinol Angelate, Nodakenin, and Decursinol of Angelica gigas Nakai in Human Plasma by UHPLC-MS/MS: Application to Pharmacokinetic Study. Molecules 23:5, pages 1019.
Crossref
Saikat Dewanjee, Tarun Dua, Niloy Bhattacharjee, Anup Das, Moumita Gangopadhyay, Ritu Khanra, Swarnalata Joardar, Muhammad Riaz, Vincenzo Feo & Muhammad Zia-Ul-Haq. (2017) Natural Products as Alternative Choices for P-Glycoprotein (P-gp) Inhibition. Molecules 22:6, pages 871.
Crossref
Mohammad Asif Emran Khan Emon, Alpha Tom Kodamullil, Reagon Karki, Erfan Younesi & Martin Hofmann-Apitius. (2017) Using Drugs as Molecular Probes: A Computational Chemical Biology Approach in Neurodegenerative Diseases. Journal of Alzheimer's Disease 56:2, pages 677-686.
Crossref
Wei Wu, Su-Ni Tang, Yong Zhang, Manohar Puppala, Timothy K. Cooper, Chengguo Xing, Cheng Jiang & Junxuan Lü. (2017) Prostate Cancer Xenograft Inhibitory Activity and Pharmacokinetics of Decursinol, a Metabolite of Angelica gigas Pyranocoumarins, in Mouse Models . The American Journal of Chinese Medicine 45:08, pages 1773-1792.
Crossref
Jeong-Jun Lee, Suyeong Nam, Ju-Hwan Park, Song Yi Lee, Jae Young Jeong, Jae-Young Lee, Wie-Soo Kang, In-Soo Yoon, Dae-Duk Kim & Hyun-Jong Cho. (2016) Nanocomposites based on Soluplus and Angelica gigas Nakai extract fabricated by an electrohydrodynamic method for oral administration. Journal of Colloid and Interface Science 484, pages 146-154.
Crossref
Dominique Turck, Jean-Louis Bresson, Barbara Burlingame, Tara Dean, Susan Fairweather-Tait, Marina Heinonen, Karen Ildico Hirsch-Ernst, Inge Mangelsdorf, Harry McArdle, Androniki Naska, Monika Neuhäuser-Berthold, Grażyna Nowicka, Kristina Pentieva, Yolanda Sanz, Alfonso Siani, Anders Sjödin, Martin Stern, Daniel Tomé, Marco Vinceti, Peter Willatts, Karl-Heinz Engel, Rosangela Marchelli, Annette Pöting, Morten Poulsen, Josef Schlatter, Emanuela Turla & Hendrik van Loveren. (2016) Safety of EstroG-100 ™ as a novel food pursuant to Regulation (EC) No 258/97 . EFSA Journal 14:10, pages e04589.
Crossref
Jeong-Jun Lee, Ju-Hwan Park, Jae-Young Lee, Jae Young Jeong, Song Yi Lee, In-Soo Yoon, Wie-Soo Kang, Dae-Duk Kim & Hyun-Jong Cho. (2016) Omega-3 fatty acids incorporated colloidal systems for the delivery of Angelica gigas Nakai extract. Colloids and Surfaces B: Biointerfaces 140, pages 239-245.
Crossref
Zhi Zheng, Hyewon Seo, Hyun Jung Kwak, Ki Young Kim, Jin Hee Ahn, Myung Ae Bae & Jin Sook Song. (2016) Pharmacokinetic characterization of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone, a novel 11β-hydroxysteroid dehydrogenase type 1 inhibitor in rats. Archives of Pharmacal Research 39:4, pages 492-498.
Crossref
Tae Woo Oh, Ki-Ho Park, Hyo Won Jung & Yong-Ki Park. (2015) Neuroprotective effect of the hairy root extract of Angelica gigas NAKAI on transient focal cerebral ischemia in rats through the regulation of angiogenesis. BMC Complementary and Alternative Medicine 15:1.
Crossref
Kwang-Jin Kim, Jeong-Tae Yeon, Sik-Won Choi, Seong-Hee Moon, Byung Jun Ryu, Ri Yu, Sang-Joon Park, Seong Hwan Kim & Young-Jin Son. (2015) Decursin inhibits osteoclastogenesis by downregulating NFATc1 and blocking fusion of pre-osteoclasts. Bone 81, pages 208-216.
Crossref
Junxuan Lü, Jinhui Zhang, Li Li, Cheng Jiang & Chengguo Xing. (2015) Cancer Chemoprevention with Korean Angelica: Active Compounds, Pharmacokinetics, and Human Translational Considerations. Current Pharmacology Reports 1:6, pages 373-381.
Crossref
Jin-Hwan Kwon, Min-Seok Han, Bu-Min Lee & Yong-Moon Lee. (2015) Inhibitory effect of Angelica gigas extract powder on induced inflammatory cytokines in rats osteoarthritis. Analytical Science and Technology 28:4, pages 260-269.
Crossref
Jun-Won Yun, Jeong-Hwan Che, Euna Kwon, Yun-Soon Kim, Seung-Hyun Kim, Ji-Ran You, Woo Ho Kim, Hyeon Hoe Kim & Byeong-Cheol Kang. (2015) Safety evaluation of Angelica gigas: Genotoxicity and 13-weeks oral subchronic toxicity in rats. Regulatory Toxicology and Pharmacology 72:3, pages 473-480.
Crossref
Jingpei Piao, Jae-Young Lee, Jin Bae Weon, Choong Je Ma, Hyun-Jeong Ko, Dae-Duk Kim, Wie-Soo Kang & Hyun-Jong Cho. (2015) Angelica gigas Nakai and Soluplus-Based Solid Formulations Prepared by Hot-Melting Extrusion: Oral Absorption Enhancing and Memory Ameliorating Effects. PLOS ONE 10:4, pages e0124447.
Crossref
Jinhui Zhang, Li Li, Suni Tang, Thomas W. Hale, Chengguo Xing, Cheng Jiang & Junxuan Lü. (2015) Cytochrome P450 Isoforms in the Metabolism of Decursin and Decursinol Angelate from Korean Angelica. The American Journal of Chinese Medicine 43:06, pages 1211-1230.
Crossref
Hossam M. Abdallah, Ahmed M. Al-Abd, Riham Salah El-Dine & Ali M. El-Halawany. (2015) P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review. Journal of Advanced Research 6:1, pages 45-62.
Crossref
Ramón Cacabelos, Pablo Cacabelos, Clara Torrellas, Iván Tellado & Juan C. Carril. 2014. Pharmacogenomics in Drug Discovery and Development. Pharmacogenomics in Drug Discovery and Development 323 556 .
You Hwa Son, Jin Sook Song, Seong Hwan Kim & Jiyeon Kim. (2013) Pharmacokinetic characterization of CK2 inhibitor CX-4945. Archives of Pharmacal Research 36:7, pages 840-845.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.