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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 10
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General Xenobiochemistry

Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD

Xiaoai HeHaikou People’s Hospital and Affiliated Haikou Hospital of Xiangya Medical School, Central South University, Haikou, Hainan, P.R. China
,
Xi LuoResearch Institute of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, P.R. China
,
Zhi LiuHunan Tiger Xiangya Drug R&D Co., Ltd, Changsha, Hunan, P.R. China
,
Gaoyun HuChemistry Section, Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, P.R. China.
&
Zeneng ChengResearch Institute of Drug Metabolism and Pharmacokinetics, School of Pharmaceutical Sciences, Central South University, Changsha, Hunan, P.R. ChinaCorrespondence[email protected]
Pages 844-850 | Received 10 Apr 2011, Accepted 16 May 2011, Published online: 16 Jun 2011

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Linling Li, Xi Luo & Zeneng Cheng. (2021) In vitro inhibition and induction of human liver cytochrome P450 enzymes by a novel anti-fibrotic drug fluorofenidone. Xenobiotica 51:7, pages 745-751.
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Articles from other publishers (2)

Kunjie Li, Xingjie Guo, Feng Qin, Zhili Xiong, Longshan Zhao & Jia Yu. (2018) Identification of the cytochrome P450 enzymes involved in the oxidative metabolism of trantinterol using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. RSC Advances 8:60, pages 34764-34772.
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Wang-Hui Jing, Yue-Lin Song, Ru Yan & Yi-Tao Wang. (2013) Identification of cytochrome P450 isoenzymes involved in metabolism of (+)-praeruptorin A, a calcium channel blocker, by human liver microsomes using ultra high-performance liquid chromatography coupled with tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 77, pages 175-188.
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