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Ayomide Victor Atoki, Patrick Maduabuchi Aja, Tijjani Salihu Shinkafi, Erick Nyakundi Ondari & Chinaza Godswill Awuchi. (2023) Naringenin: its chemistry and roles in neuroprotection. Nutritional Neuroscience 0:0, pages 1-30.
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Rizwan Arshad, Saira Masood, Hafiz Rizwan Sharif, Gulden Goksen, Baojun Xu & Muhammad Faisal Manzoor. (2023) New Insights into Health-Promoting Effects of Nobiletin from Citrus Fruits. Food Reviews International 0:0, pages 1-20.
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Abhisek Karn, Chengying Zhao, Feilong Yang, Jiefen Cui, Zili Gao, Minqi Wang, Fengzhong Wang, Hang Xiao & Jinkai Zheng. (2021) In-vivo biotransformation of citrus functional components and their effects on health. Critical Reviews in Food Science and Nutrition 61:5, pages 756-776.
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Zeinab T. Abdel Shakour, Nesrin M. Fayek & Mohamed A. Farag. (2020) How do biocatalysis and biotransformation affect Citrus dietary flavonoids chemistry and bioactivity? A review. Critical Reviews in Biotechnology 40:5, pages 689-714.
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Hao Wang, Lin Dong, Fangfei Qu, Huimin He, Wei Sun, Yuqing Man & Hongjie Jiang. (2020) Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Pharmaceutical Biology 58:1, pages 352-356.
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Articles from other publishers (42)
Raziel Alejandro Arias-Sánchez, Luz Torner & Bertha Fenton Navarro. (2023) Polyphenols and Neurodegenerative Diseases: Potential Effects and Mechanisms of Neuroprotection. Molecules 28:14, pages 5415.
Crossref
Crossref
Masazumi Iwashita, Ryuta Shioi, Mitsuru Sugiyama, Kohjiro Hashizume, Toshiyuki Kan, Shiomi Naito, Hidemichi Takai, Yuto Kawase, Toshihide Hamabe-Horiike, Yasufumi Katanasaka, Yoichi Sunagawa & Tatsuya Morimoto. (2023) Monodemethylated Metabolites of Orally Administered Nobiletin: Identification and Quantitation in Rat Plasma and Tissues. Journal of Agricultural and Food Chemistry 71:26, pages 10028-10036.
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Crossref
Shiwei Su, Denggao Zhao, Bo Yuan, Yanyan Ma, Siyue Zhu, Kuangyu Xu, Grace Lee, Chi-Tang Ho & Qingrong Huang. (2022) Biosynthesis of 6- and 7-Mono-Demethylated Nobiletins by a Newly Isolated Strain of Yeast. Journal of Agricultural and Food Chemistry 70:49, pages 15439-15448.
Crossref
Crossref
Yanping Xin, Ting Zheng, Man Zhang, Ruiqiang Zhang, Siyue Zhu, Dongli Li, Denggao Zhao, Yanyan Ma, Chi-Tang Ho & Qingrong Huang. (2022) Demethylnobiletin and its major metabolites: Efficient preparation and mechanism of their anti-proliferation activity in HepG2 cells. Food Science and Human Wellness 11:5, pages 1191-1200.
Crossref
Crossref
Larissa Gabriela Faqueti, Layzon Antonio Lemos da Silva, Gabriela Salim Gomes Moreira, Scheila Kraus, Gustavo dos Santos Catarina de Jesus, Luciana Aparecida Honorato, Bibiana Verlindo de Araujo, Adair Roberto Soares dos Santos, Teresa Dalla Costa & Maique Weber Biavatti. (2022) Preclinical Pharmacokinetic and Pharmacodynamic Investigation of 5’-Methoxynobiletin from Ageratum conyzoides: In vivo and In silico Approaches. Pharmaceutical Research 39:9, pages 2135-2145.
Crossref
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Diana Rodríguez-Vera, Antonio Abad-García, Nancy Vargas-Mendoza, Rodolfo Pinto-Almazán, EuniceD Farfán-García, JoséA Morales-González & MarvinA Soriano-Ursúa. (2022) Polyphenols as potential enhancers of stem cell therapy against neurodegeneration. Neural Regeneration Research 17:10, pages 2093.
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Crossref
Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Fašmon Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Johannes Westendorf, Paola Manini, Fabiola Pizzo & Birgit Dusemund. (2021) Safety and efficacy of feed additives consisting of expressed sweet orange peel oil and its fractions from Citrus sinensis (L.) Osbeck for use in all animal species (FEFANA asbl). EFSA Journal 19:11.
Crossref
Crossref
Yuan Wu, Chien-shan Cheng, Qiong Li, Jing-xian Chen, Ling-ling Lv, Jia-yue Xu, Kai-yuan Zhang & Lan Zheng. (2021) The Application of Citrus folium in Breast Cancer and the Mechanism of Its Main Component Nobiletin: A Systematic Review. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-15.
Crossref
Crossref
Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Maryline Kouba, Mojca Fas\̌mon Durjava, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Johannes Westendorf, Paola Manini, Fabiola Pizzo & Birgit Dusemund. (2021) Safety and efficacy of a feed additive consisting of expressed mandarin oil from the fruit peels of Citrus reticulata Blanco for use in all animal species (FEFANA asbl). EFSA Journal 19:6.
Crossref
Crossref
Yasushi Yamazoe & Masahiro Tohkin. (2021) Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template. Drug Metabolism and Pharmacokinetics 38, pages 100357.
Crossref
Crossref
Meiyan Wang, Hui Zhao, Xiang Wen, Chi‐Tang Ho & Shiming Li. (2020) Citrus flavonoids and the intestinal barrier: Interactions and effects. Comprehensive Reviews in Food Science and Food Safety 20:1, pages 225-251.
Crossref
Crossref
Siddharth S. Kesharwani, Pooja Mallya, Vadikari Arun Kumar, Vikas Jain, Swagat Sharma & Surajit Dey. (2020) Nobiletin as a Molecule for Formulation Development: An Overview of Advanced Formulation and Nanotechnology-Based Strategies of Nobiletin. AAPS PharmSciTech 21:6.
Crossref
Crossref
Johanna Weiss, Giuseppe Gattuso, Davide Barreca & Walter Emil Haefeli. (2020) Nobiletin, sinensetin, and tangeretin are the main perpetrators in clementines provoking food-drug interactions in vitro. Food Chemistry 319, pages 126578.
Crossref
Crossref
Milad Ashrafizadeh, Ali Zarrabi, Sedigheh Saberifar, Farid Hashemi, Kiavash Hushmandi, Fardin Hashemi, Ebrahim Rahmani Moghadam, Reza Mohammadinejad, Masoud Najafi & Manoj Garg. (2020) Nobiletin in Cancer Therapy: How This Plant Derived-Natural Compound Targets Various Oncogene and Onco-Suppressor Pathways. Biomedicines 8:5, pages 110.
Crossref
Crossref
Nadya M. Morrow, Amy C. Burke, Joshua P. Samsoondar, Kyle E. Seigel, Andrew Wang, Dawn E. Telford, Brian G. Sutherland, Conor O'Dwyer, Gregory R. Steinberg, Morgan D. Fullerton & Murray W. Huff. (2020) The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat-fed mice independent of AMPK. Journal of Lipid Research 61:3, pages 387-402.
Crossref
Crossref
Entesar Hanan & Farhan J. Ahmad. 2020. Nanomedicine for Bioactives. Nanomedicine for Bioactives
231
257
.
Huijuan Zhang, Guifang Tian, Chengying Zhao, Yanhui Han, Christina DiMarco-Crook, Chang Lu, Yuming Bao, Chengxiu Li, Hang Xiao & Jinkai Zheng. (2019) Characterization of polymethoxyflavone demethylation during drying processes of citrus peels. Food & Function 10:9, pages 5707-5717.
Crossref
Crossref
Goh, Tan, Goh, Chan, Pusparajah, Lee & Goh. (2019) Nobiletin and Derivatives: Functional Compounds from Citrus Fruit Peel for Colon Cancer Chemoprevention. Cancers 11:6, pages 867.
Crossref
Crossref
Justine Renaud & Maria-Grazia Martinoli. (2019) Considerations for the Use of Polyphenols as Therapies in Neurodegenerative Diseases. International Journal of Molecular Sciences 20:8, pages 1883.
Crossref
Crossref
Theodomir Dusabimana, So Ra Kim, Hye Jung Kim, Sang Won Park & Hwajin Kim. (2019) Nobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis. Experimental & Molecular Medicine 51:4, pages 1-16.
Crossref
Crossref
Bao Yang, Huiling Liu, Jiali Yang, Vijai Kumar Gupta & Yueming Jiang. (2018) New insights on bioactivities and biosynthesis of flavonoid glycosides. Trends in Food Science & Technology 79, pages 116-124.
Crossref
Crossref
Danielle R. Gonçalves, John A. Manthey, Paulo I. da Costa, Marilia C. M. Rodrigues & Thais B. Cesar. (2018) Analysis of Fluorescence Spectra of Citrus Polymethoxylated Flavones and Their Incorporation into Mammalian Cells. Journal of Agricultural and Food Chemistry 66:28, pages 7531-7541.
Crossref
Crossref
Somchaiya Surichan, Randolph R. Arroo, Ketan Ruparelia, Aristidis M. Tsatsakis & Vasilis P. Androutsopoulos. (2018) Nobiletin bioactivation in MDA-MB-468 breast cancer cells by cytochrome P450 CYP1 enzymes. Food and Chemical Toxicology 113, pages 228-235.
Crossref
Crossref
Asmaa I. Owis. 2018.
509
530
.
Su-Ling Zeng, Li Duan, Bai-Zhong Chen, Ping Li & E-Hu Liu. (2017) Chemicalome and metabolome profiling of polymethoxylated flavonoids in Citri Reticulatae Pericarpium based on an integrated strategy combining background subtraction and modified mass defect filter in a Microsoft Excel Platform. Journal of Chromatography A 1508, pages 106-120.
Crossref
Crossref
Dylan T. Marsh, Sukanya Das, Jessica Ridell & Scott D. Smid. (2017) Structure-activity relationships for flavone interactions with amyloid β reveal a novel anti-aggregatory and neuroprotective effect of 2′,3′,4′-trihydroxyflavone (2-D08). Bioorganic & Medicinal Chemistry 25:14, pages 3827-3834.
Crossref
Crossref
Akira Nakajima, Yasushi Ohizumi & Kiyofumi Yamada. 2017. Neuroprotective Effects of Phytochemicals in Neurological Disorders. Neuroprotective Effects of Phytochemicals in Neurological Disorders
421
433
.
Koichi Haraguchi, Yoshiko Ito, Masae Takagi, Yukiko Fujii, Kouji H. Harada & Akio Koizumi. (2016) Levels, profiles and dietary sources of hydroxylated PCBs and hydroxylated and methoxylated PBDEs in Japanese women serum samples. Environment International 97, pages 155-162.
Crossref
Crossref
Shivesh Ghura, Leon Tai, Ming Zhao, Nicole Collins, Chun-Tao Che, Katherine M. Warpeha & Mary Jo LaDu. (2016) Arabidopsis thaliana extracts optimized for polyphenols production as potential therapeutics for the APOE-modulated neuroinflammation characteristic of Alzheimer’s disease in vitro. Scientific Reports 6:1.
Crossref
Crossref
Anna Berim & David R. Gang. (2015) Methoxylated flavones: occurrence, importance, biosynthesis. Phytochemistry Reviews 15:3, pages 363-390.
Crossref
Crossref
Xianbao Shi, Brianna Mackie, Gang Zhang, Shuman Yang, Yonggui Song, Dan Su, Yali Liu & Lina Shan. (2016) Identification of the Metabolic Enzyme Involved Morusin Metabolism and Characterization of Its Metabolites by Ultraperformance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS/MS). Evidence-Based Complementary and Alternative Medicine 2016, pages 1-10.
Crossref
Crossref
Hao Huang, Linfu Li, Weimei Shi, Hai Liu, Jianqiong Yang, Xiaoliang Yuan & Longhuo Wu. (2016)
The Multifunctional Effects of Nobiletin and Its Metabolites
In Vivo
and
In Vitro
. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-14.
Crossref
Crossref
David Julian McClements, Liqiang Zou, Ruojie Zhang, Laura Salvia-Trujillo, Taha Kumosani & Hang Xiao. (2015) Enhancing Nutraceutical Performance Using Excipient Foods: Designing Food Structures and Compositions to Increase Bioavailability. Comprehensive Reviews in Food Science and Food Safety 14:6, pages 824-847.
Crossref
Crossref
Denisa Margină, Mihaela Ilie, Daniela Grădinaru, Vasilis P. Androutsopoulos, Demetrios Kouretas & Aristidis M. Tsatsakis. (2015) Natural products—friends or foes?. Toxicology Letters 236:3, pages 154-167.
Crossref
Crossref
David Julian McClements, Fang LiHang Xiao. (2015) The Nutraceutical Bioavailability Classification Scheme: Classifying Nutraceuticals According to Factors Limiting their Oral Bioavailability. Annual Review of Food Science and Technology 6:1, pages 299-327.
Crossref
Crossref
Anna Berim, Min-Jeong Kim & David R. Gang. (2015) Identification of a Unique 2-Oxoglutarate-Dependent Flavone 7-O-Demethylase Completes the Elucidation of the Lipophilic Flavone Network in Basil. Plant and Cell Physiology 56:1, pages 126-136.
Crossref
Crossref
Randolph R. J. Arroo, Kenneth Beresford, Avninder S. Bhambra, Mike Boarder, Roberta Budriesi, Zhong Cheng, Matteo Micucci, Ketan C. Ruparelia, Somchaiya Surichan & Vasilis P. Androutsopoulos. (2014) Phytoestrogens as natural prodrugs in cancer prevention: towards a mechanistic model. Phytochemistry Reviews 13:4, pages 853-866.
Crossref
Crossref
Xiaolan Ye, Di Cao, Xin Zhao, Fenyun Song, Qinghua Huang, Guorong Fan & Fuhai Wu. (2014) Chemical fingerprint and metabolic profile analysis of Citrus reticulate ‘Chachi’ decoction by HPLC-PDA-IT-MSn and HPLC-Quadrupole-Orbitrap-MS method. Journal of Chromatography B 970, pages 108-120.
Crossref
Crossref
Osamu Kimura, Chiho Ohta, Nobuyuki Koga, Koichi Haraguchi, Yoshihisa Kato & Tetsuya Endo. (2014) Carrier-mediated uptake of nobiletin, a citrus polymethoxyflavonoid, in human intestinal Caco-2 cells. Food Chemistry 154, pages 145-150.
Crossref
Crossref
Shiming Li, Hong Wang, Limin Guo, Hui Zhao & Chi-Tang Ho. (2014) Chemistry and bioactivity of nobiletin and its metabolites. Journal of Functional Foods 6, pages 2-10.
Crossref
Crossref
Jinkai Zheng, Mingyue Song, Ping Dong, Peiju Qiu, Shanshan Guo, Zhimei Zhong, Shiming Li, Chi-Tang Ho & Hang Xiao. (2013) Identification of novel bioactive metabolites of 5-demethylnobiletin in mice. Molecular Nutrition & Food Research 57:11, pages 1999-2007.
Crossref
Crossref
Daniel M. Müller & Katharina M. Rentsch. (2011) Vergiftung oder Krankheit? Screening mit LC‐MS(n). Nachrichten aus der Chemie 59:11, pages 1078-1080.
Crossref
Crossref