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Kathryn Pickup, Jonathan Wills, Alison Rodrigues, Huw B. Jones, Chris Page, Scott Martin, Sunil Sarda & Ian Wilson. (2014) The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse. Xenobiotica 44:2, pages 164-173.
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Benoit Cox, Patrick Barton, Reiner Class, Hannah Coxhead, Claude Delatour, Eric Gillent, Jamie Henshall, Emre M. Isin, Lloyd King & Jean-Pierre Valentin. (2022) Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation. Biomaterials and Biosystems 7, pages 100054.
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Lee A. Gethings, Nicola Gray, Robert S. Plumb & Ian D. Wilson. (2021) Proteomic consequences of the deletion of cytochrome P450 (CYP450) reductase in mice. Journal of Chromatography B 1179, pages 122803.
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Peter R. Bradshaw, Toby J. Athersuch, Andrew V. Stachulski & Ian D. Wilson. (2020) Acyl glucuronide reactivity in perspective. Drug Discovery Today 25:9, pages 1639-1650.
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Nicola Gray, Lee A. Gethings, Robert S. Plumb & Ian D. Wilson. (2020) UHPLC-MS-Based Lipidomic and Metabonomic Investigation of the Metabolic Phenotypes of Wild Type and Hepatic CYP Reductase Null (HRN) Mice. Journal of Pharmaceutical and Biomedical Analysis 186, pages 113318.
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Renato J. Scialis, Lauren M. Aleksunes, Iván L. Csanaky, Curtis D. Klaassen & José E. Manautou. (2019) Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites. Drug Metabolism and Disposition 47:10, pages 1080-1092.
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C. E. Wilson, A. P. Dickie, K. Schreiter, R. Wehr, E. M. Wilson, J. Bial, N. Scheer, I. D. Wilson & R. J. Riley. (2018) The pharmacokinetics and metabolism of diclofenac in chimeric humanized and murinized FRG mice. Archives of Toxicology 92:6, pages 1953-1967.
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Kathryn Pickup, Scott Martin, Elizabeth A. Partridge, Huw B. Jones, Jonathan Wills, Tim Schulz-Utermoehl, Alan McCarthy, Alison Rodrigues, Chris Page, Kerry Ratcliffe, Sunil Sarda & Ian D. Wilson. (2016) Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice. Archives of Toxicology 91:7, pages 2643-2653.
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K. Samuelsson, N. Scheer, I. Wilson, C.R. Wolf & C.J. Henderson. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III
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R. A. Stringer, S. Ferreira, J. Rose & S. Ronseaux. (2016) Application of Osmotic Pumps for Sustained Release of 1-Aminobenzotriazole and Inhibition of Cytochrome P450 Enzymes in Mice: Model Comparison with the Hepatic P450 Reductase Null Mouse. Drug Metabolism and Disposition 44:8, pages 1213-1216.
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James A. Akingbasote, Alison J. Foster, Ian Wilson, Sunil Sarda, Huw B. Jones & J. Gerry Kenna. (2015) Hepatic effects of repeated oral administration of diclofenac to hepatic cytochrome P450 reductase null (HRN™) and wild-type mice. Archives of Toxicology 90:4, pages 853-862.
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C. Roland Wolf, Yury Kapelyukh, Nico Scheer & Colin J. Henderson. 2015. New Horizons in Predictive Drug Metabolism and Pharmacokinetics. New Horizons in Predictive Drug Metabolism and Pharmacokinetics
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Aidan Grimsley, Alison Foster, Richard Gallagher, Michael Hutchison, Anders Lundqvist, Kathryn Pickup, Ian D. Wilson & Kristin Samuelsson. (2014) A comparison of the metabolism of midazolam in C57BL/6J and hepatic reductase null (HRN) mice. Biochemical Pharmacology 92:4, pages 701-711.
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Sunil Sarda, Elizabeth A. Partridge, Kathryn Pickup, Alan McCarthy & Ian D. Wilson. (2013) HPLC–MS Profiling and Structural Identification of [14C]-Diclofenac Metabolites in Mouse Bile. Chromatographia 77:3-4, pages 233-239.
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