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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 2
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General Xenobiochemistry

A high throughput in vitro mrp2 assay to predict in vivo biliary excretion

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Pages 157-163 | Received 12 Jul 2011, Accepted 09 Aug 2011, Published online: 02 Oct 2011

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Olivier Fardel, Marc Le Vee, Elodie Jouan, Claire Denizot & Yannick Parmentier. (2015) Nature and uses of fluorescent dyes for drug transporter studies. Expert Opinion on Drug Metabolism & Toxicology 11:8, pages 1233-1251.
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Kyle S. Saitta, Carmen Zhang, Kang Kwang Lee, Kazunori Fujimoto, Matthew R. Redinbo & Urs A. Boelsterli. (2014) Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics. Xenobiotica 44:1, pages 28-35.
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Federico Colombo, Hugo Poirier, Nathalie Rioux, Maria Arias Montecillo, Jianmin Duan & Maria D. Ribadeneira. (2013) A membrane vesicle-based assay to enable prediction of human biliary excretion. Xenobiotica 43:10, pages 915-919.
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Kimberley M. Hanssen, Michelle Haber & Jamie I. Fletcher. (2021) Targeting multidrug resistance-associated protein 1 (MRP1)-expressing cancers: Beyond pharmacological inhibition. Drug Resistance Updates 59, pages 100795.
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Xia Wen, Melanie S. Joy & Lauren M. Aleksunes. (2017) In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants. Pharmaceutical Research 34:8, pages 1637-1647.
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Naoki Tanimizu, Kota Kaneko, Tohru Itoh, Norihisa Ichinohe, Masayuki Ishii, Toru Mizuguchi, Koichi Hirata, Atsushi Miyajima & Toshihiro Mitaka. (2016) Intrahepatic bile ducts are developed through formation of homogeneous continuous luminal network and its dynamic rearrangement in mice. Hepatology 64:1, pages 175-188.
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Richard A. Thompson, Emre M. Isin, Monday O. Ogese, Jerome T. Mettetal & Dominic P. Williams. (2016) Reactive Metabolites: Current and Emerging Risk and Hazard Assessments. Chemical Research in Toxicology 29:4, pages 505-533.
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Franck A. Atienzar, Eric I. Novik, Helga H. Gerets, Amit Parekh, Claude Delatour, Alvaro Cardenas, James MacDonald, Martin L. Yarmush & Stéphane Dhalluin. (2014) Predictivity of dog co-culture model, primary human hepatocytes and HepG2 cells for the detection of hepatotoxic drugs in humans. Toxicology and Applied Pharmacology 275:1, pages 44-61.
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Nathalie Rioux, Edith Bellavance, Hugo Poirier, Mariève Dupuis, Michel Garneau, Maria D. Ribadeneira & Jianmin Duan. (2013) A strategy to reduce biliary clearance in early drug discovery. Journal of Pharmacological and Toxicological Methods 68:3, pages 346-348.
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