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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 2
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Clinical Pharmacokinetics and Metabolism

Effect of genistein on the activities of cytochrome P450 3A and P-glycoprotein in Chinese healthy participants

C.-Q. XiaoThe First People’s Hospital of Chenzhou City, Chenzhou, Hunan, P. R. China
,
R. ChenThe First People’s Hospital of Chenzhou City, Chenzhou, Hunan, P. R. China
,
J. LinThe First People’s Hospital of Chenzhou City, Chenzhou, Hunan, P. R. China
,
G. WangPharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, P. R. China
,
Y. ChenPharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, P. R. China
,
Z.-R. TanPharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, P. R. China
&
H.-H. ZhouPharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University, Changsha, Hunan, P. R. ChinaCorrespondence[email protected]
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Pages 173-178 | Received 14 Jul 2011, Accepted 16 Aug 2011, Published online: 26 Sep 2011

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Teruo Murakami, Erik Bodor & Nicholas Bodor. (2020) Modulation of expression/function of intestinal P-glycoprotein under disease states. Expert Opinion on Drug Metabolism & Toxicology 16:1, pages 59-78.
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Martin J. J. Ronis. (2016) Effects of soy containing diet and isoflavones on cytochrome P450 enzyme expression and activity. Drug Metabolism Reviews 48:3, pages 331-341.
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Zhe Wang, Li Wang, Meng-ming Xia, Wei Sun, Cheng-ke Huang, Xiao Cui, Guo-xin Hu, Qing-quan Lian & Zeng-shou Wang. (2015) Pharmacokinetics Interaction between Imatinib and Genistein in Rats. BioMed Research International 2015, pages 1-7.
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C.P. Yu, Y.W. Hsieh, S.P. Lin, Y.C. Chi, P. Hariharan, P.D.L. Chao & Y.C. Hou. (2014) Potential modulation on P-glycoprotein and CYP3A by soymilk and miso: In vivo and ex-vivo studies. Food Chemistry 149, pages 25-30.
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Quan Zhou, Zhen Ye, Zourong Ruan & Su Zeng. (2013) Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe. Journal of Ethnopharmacology 146:3, pages 744-749.
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