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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 3
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Animal Pharmacokinetics and Metabolism

Bioavailability and pharmacokinetics of S-propargyl-L-cysteine, a novel cardioprotective agent, after single and multiple doses in Beagle dogs

Yuanting ZhengDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China
,
Jialin XuDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China
,
Guo MaDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China
,
Jinlian ZhangDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China
,
Qing ZhuDepartment of Pharmacology, School of Pharmacy and Institute of Biomedical Sciences, Fudan University, Shanghai, China
,
Hongrui LiuDepartment of Pharmacology, School of Pharmacy and Institute of Biomedical Sciences, Fudan University, Shanghai, China
,
Peng ZhangDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, China
,
Yizhun ZhuDepartment of Pharmacology, School of Pharmacy and Institute of Biomedical Sciences, Fudan University, Shanghai, China
&
Weimin CaiDepartment of Clinical Pharmacy, School of Pharmacy, Fudan University, Shanghai, ChinaCorrespondence[email protected]
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Pages 304-309 | Received 04 Aug 2011, Accepted 23 Aug 2011, Published online: 01 Oct 2011

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Guo Ma, Lin Zhang, Peng Zhang, Xingfei Bao, Ning Zhou, Qingling Shi, Yuanting Zheng, Hongrui Liu, Fengjiao Bu, Ying Zhang, Wenjie Huang, Fen Wang, Yizhun Zhu & Weimin Cai. (2015) Physicochemical characteristics and gastrointestinal absorption behaviors of S-propargyl-cysteine, a potential new drug candidate for cardiovascular protection and antitumor treatment. Xenobiotica 45:4, pages 322-334.
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Articles from other publishers (6)

Ming-Cong Zheng, Wen-Ting Tang, Lu-Lu Yu, Xun-Jia Qian, Jie Ren, Jie-Jia Li, Wei-Wei Rong, Jun-Xu Li & Qing Zhu. (2022) Preclinical Pharmacokinetics and Bioavailability of Oxypeucedanin in Rats after Single Intravenous and Oral Administration. Molecules 27:11, pages 3570.
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Hui Zhao & Wei Zhao. (2019) Development of a high resolution mass spectrometry method for the determination of danshensu and salvianolic acid B. SN Applied Sciences 1:5.
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Minjun Wang, Wenbo Tang, Hong Xin & Yi Zhun Zhu. (2016) S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway. PLOS ONE 11:9, pages e0163289.
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Jianfeng Wang, Lishuang Liang, Qiongyu Zhang, Xingang Li & Zhijian Fu. (2013) Preclinical pharmacokinetics, tissue distribution and excretion studies of a potential analgesics – corydaline using an ultra performance liquid chromatography–tandem mass spectrometry. Journal of Chromatography B 942-943, pages 70-76.
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RONG SUO, ZHAN-ZHI ZHAO, ZHI-HAN TANG, ZHONG REN, XING LIU, LU-SHAN LIU, ZUO WANG, CHAO-KE TANG, DANG-HENG WEI & ZHI-SHENG JIANG. (2013) Hydrogen sulfide prevents H2O2-induced senescence in human umbilical vein endothelial cells through SIRT1 activation. Molecular Medicine Reports 7:6, pages 1865-1870.
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Changchuan Guo, Yan Jiang, Li Li, Lan Hong, Yuqing Wang, Qian Shen, Yan Lou, Haihong Hu, Hui Zhou, Lushan Yu, Huidi Jiang & Su Zeng. (2013) Application of a liquid chromatography–tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of Dactylicapnos scandens in rats. Journal of Pharmaceutical and Biomedical Analysis 74, pages 92-100.
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