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Xiaoying Ruan, Jiaqi Yu, Hao Miao, Renjie Li & Zhenbo Tong. (2022) Remdesivir powders manufactured by jet milling for potential pulmonary treatment of COVID-19. Pharmaceutical Development and Technology 27:6, pages 635-645.
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E. Zeqiri, M. A. da Silva, S. R. Aspinall, E. Hoffman, V. Hutter & M. T. Cook. (2024) Thermoreversible gels for the encapsulation of macrophages: evaluation of polymer type on rheology and cytocompatibility. RSC Applied Polymers.
Crossref
Crossref
Petra Party & Rita Ambrus. (2023) Investigation of Physico-Chemical Stability and Aerodynamic Properties of Novel “Nano-in-Micro” Structured Dry Powder Inhaler System. Micromachines 14:7, pages 1348.
Crossref
Crossref
David Rudolph, Natalja Redinger, Katharina Schwarz, Feng Li, Gabriela Hädrich, Michaela Cohrs, Lea Ann Dailey, Ulrich E. Schaible & Claus Feldmann. (2023) Amorphous Drug Nanoparticles for Inhalation Therapy of Multidrug-Resistant Tuberculosis. ACS Nano 17:10, pages 9478-9486.
Crossref
Crossref
V. Hutter, S. Hopper, J. Skamarauskas & E. Hoffman. (2023) High content analysis of in vitro alveolar macrophage responses can provide mechanistic insight for inhaled product safety assessment. Toxicology in Vitro 86, pages 105506.
Crossref
Crossref
Kohei Togami, Arisa Ogasawara, Sayo Irie, Kenji Iwata, Kotaro Yamaguchi, Hitoshi Tada & Sumio Chono. (2022) Improvement of the pharmacokinetics and antifibrotic effects of nintedanib by intrapulmonary administration of a nintedanib–hydroxypropyl-γ-cyclodextrin inclusion complex in mice with bleomycin-induced pulmonary fibrosis. European Journal of Pharmaceutics and Biopharmaceutics 172, pages 203-212.
Crossref
Crossref
Christopher R. Wellaway, Ian R. BaldwinPaul Bamborough, Daniel BarkerMichelle A. BartholomewChun-wa Chung, Birgit Dümpelfeld, John P. EvansNeal J. FazakerleyPaul HomesSteven P. KeelingXiao Q. LewellFinlay W. McNabJoanne MorleyDeborah NeedhamMargarete NeuAntoon J. M. van OosterhoutAnshu PalFriedrich B. M. Reinhard, Francesco Rianjongdee, Craig M. RobertsonPaul RowlandRishi R. Shah, Emma B. SherriffLisa A. SloanSimon TeagueDaniel A. ThomasNatalie WellawayJustyna Wojno-PiconJames M. WoolvenDiane M. Coe. (2021) Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism. Journal of Medicinal Chemistry 65:1, pages 633-664.
Crossref
Crossref
Jong-Hwan Woo, Ki Cheon Kim, Hyeon-Young Kim, In-Hyeon Kim, Sung-Hwan Kim & Kyuhong Lee. (2021) Comparative toxicity of polyhexamethylene guanidine phosphate in three strains of rats. Molecular & Cellular Toxicology 18:1, pages 57-69.
Crossref
Crossref
Yoen-Ju Son, Danforth P. Miller & Jeffry G. Weers. (2021) Optimizing Spray-Dried Porous Particles for High Dose Delivery with a Portable Dry Powder Inhaler. Pharmaceutics 13:9, pages 1528.
Crossref
Crossref
Emmanuel Gbenga Olumayede, B. Babalola & I. Oghenovo. 2021. Trace Elements and Their Effects on Human Health and Diseases. Trace Elements and Their Effects on Human Health and Diseases.
Michela Gregori, Stuart W. Naylor, Mark C. Freke, Ronnie Chamanza, Alessandro Piaia & A. Peter Hall. (2020) Multisite Analysis of Lesions in the Respiratory Tract of the Rat and Nonhuman Primate (Cynomolgus Monkey) Exposed to Air, Vehicle, and Inhaled Small Molecule Compounds. Toxicologic Pathology 49:2, pages 349-369.
Crossref
Crossref
Florence Poitout-Belissent, Shawn N. Grant & Jeffrey S. Tepper. (2020) Aspiration and Inspiration: Using Bronchoalveolar Lavage for Toxicity Assessment. Toxicologic Pathology 49:2, pages 386-396.
Crossref
Crossref
Britta Bonn & Matthew Perry. 2021. Inhaled Medicines. Inhaled Medicines
13
34
.
Alison Murray, Lindsey Cass, Kazuhiro Ito, Nicole Pagani, Darius Armstrong-James, Paras Dalal, Anna Reed & Pete Strong. (2020) PC945, a Novel Inhaled Antifungal Agent, for the Treatment of Respiratory Fungal Infections. Journal of Fungi 6:4, pages 373.
Crossref
Crossref
Shadabul Haque, Colin W. Pouton, Michelle P. McIntosh, David B Ascher, David W Keizer, Michael R. Whittaker & Lisa M. Kaminskas. (2020) The impact of size and charge on the pulmonary pharmacokinetics and immunological response of the lungs to PLGA nanoparticles after intratracheal administration to rats. Nanomedicine: Nanotechnology, Biology and Medicine 30, pages 102291.
Crossref
Crossref
Sawittree Sahakijpijarn, Chaeho Moon, John J. Koleng, Dale J. Christensen & Robert O. WilliamsIIIIII. (2020) Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing. Pharmaceutics 12:11, pages 1002.
Crossref
Crossref
Andrew M. Shen & Tamara Minko. (2020) Pharmacokinetics of inhaled nanotherapeutics for pulmonary delivery. Journal of Controlled Release 326, pages 222-244.
Crossref
Crossref
Junwei Wang, Nicolas Grégoire, Sandrine Marchand, Jörg P. Kutter, Huiling Mu, Arshnee Moodley, William Couet & Mingshi Yang. (2020) Improved antibacterial efficiency of inhaled thiamphenicol dry powders: Mathematical modelling of in vitro dissolution kinetic and in vitro antibacterial efficacy. European Journal of Pharmaceutical Sciences 152, pages 105435.
Crossref
Crossref
Sawittree Sahakijpijarn, Chaeho Moon, Xiangyu Ma, Yongchao Su, John J. Koleng, Andrei Dolocan & Robert O. WilliamsIIIIII. (2020) Using thin film freezing to minimize excipients in inhalable tacrolimus dry powder formulations. International Journal of Pharmaceutics 586, pages 119490.
Crossref
Crossref
Gregory R. HammErica BäckströmMikael BrüllsAnna NilssonNicole StrittmatterPer E. AndrénKen GrimeMarkus FridénRichard J.A. Goodwin. (2020) Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging. Journal of Aerosol Medicine and Pulmonary Drug Delivery 33:1, pages 43-53.
Crossref
Crossref
Shadabul Haque, Orlagh Feeney, Els Meeusen, Ben J. Boyd, Michelle P. McIntosh, Colin W. Pouton, Michael Whittaker & Lisa M. Kaminskas. (2019) Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats. Journal of Controlled Release 307, pages 32-43.
Crossref
Crossref
Aateka Patel, Ewelina Hoffman, Doug Ball, Jan Klapwijk, Rory T. Steven, Alex Dexter, Josephine Bunch, Daniel Baker, Darragh Murnane, Victoria Hutter, Clive Page, Lea Ann Dailey & Ben Forbes. (2019) Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis. Pharmaceutics 11:7, pages 345.
Crossref
Crossref
Antonio Llinas, Rafael Barbas, Mercè Font-Bardia, Amir Smailagic & Rafel Prohens. (2018) Derisking Development by a Cocrystallization Screen of a Novel Selective Inhaled JAK-STAT inhibitor. Crystal Growth & Design 19:1, pages 403-414.
Crossref
Crossref
Zhengwei Huang, Ling Lin, Cushla McGoverin, Hu Liu, Lili Wang, Qi (Tony) Zhou, Ming Lu & Chuanbin Wu. (2018) Dry powder inhaler formulations of poorly water-soluble itraconazole: A balance between in-vitro dissolution and in-vivo distribution is necessary. International Journal of Pharmaceutics 551:1-2, pages 103-110.
Crossref
Crossref
Mireille Hassoun, Paul G. Royall, Mark Parry, Richard D. Harvey & Ben Forbes. (2018) Design and development of a biorelevant simulated human lung fluid. Journal of Drug Delivery Science and Technology 47, pages 485-491.
Crossref
Crossref
Lilian Henriques do Amaral, Flavia Almada do Carmo, Maria Inês Amaro, Valeria Pereira de Sousa, Luiz Claudio Rodrigues Pereira da Silva, Gabriella Silva de Almeida, Carlos Rangel Rodrigues, Anne Marie Healy & Lucio Mendes Cabral. (2018) Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods. AAPS PharmSciTech 19:6, pages 2687-2699.
Crossref
Crossref
Ashlee D. Brunaugh & Hugh D.C. Smyth. (2018) Formulation techniques for high dose dry powders. International Journal of Pharmaceutics 547:1-2, pages 489-498.
Crossref
Crossref
Shadabul Haque, Michael Whittaker, Michelle P. McIntosh, Colin W. Pouton, Simon Phipps & Lisa M. Kaminskas. (2018) A comparison of the lung clearance kinetics of solid lipid nanoparticles and liposomes by following the 3H-labelled structural lipids after pulmonary delivery in rats. European Journal of Pharmaceutics and Biopharmaceutics 125, pages 1-12.
Crossref
Crossref
Ewelina Hoffman, Aateka Patel, Doug Ball, Jan Klapwijk, Val Millar, Abhinav Kumar, Abigail Martin, Rhamiya Mahendran, Lea Ann Dailey, Ben Forbes & Victoria Hutter. (2017) Morphometric Characterization of Rat and Human Alveolar Macrophage Cell Models and their Response to Amiodarone using High Content Image Analysis. Pharmaceutical Research 34:12, pages 2466-2476.
Crossref
Crossref
Abhinav Kumar, Wachirun Terakosolphan, Mireille Hassoun, Kalliopi-Kelli Vandera, Astrid Novicky, Richard Harvey, Paul G. Royall, Elif Melis Bicer, Jonny Eriksson, Katarina Edwards, Dirk Valkenborg, Inge Nelissen, Dave Hassall, Ian S. Mudway & Ben Forbes. (2017) A Biocompatible Synthetic Lung Fluid Based on Human Respiratory Tract Lining Fluid Composition. Pharmaceutical Research 34:12, pages 2454-2465.
Crossref
Crossref
Ling Lin, Guilan Quan, Tingting Peng, Zhengwei Huang, Vikramjeet Singh, Ming Lu & Chuanbin Wu. (2017) Development of fine solid-crystal suspension with enhanced solubility, stability, and aerosolization performance for dry powder inhalation. International Journal of Pharmaceutics 533:1, pages 84-92.
Crossref
Crossref
Shadabul Haque, Victoria M. McLeod, Seth Jones, Sandy Fung, Michael Whittaker, Michelle McIntosh, Colin Pouton, David J. Owen, Christopher J.H. Porter & Lisa M. Kaminskas. (2017) Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers. European Journal of Pharmaceutics and Biopharmaceutics 119, pages 408-418.
Crossref
Crossref
Nirmal Marasini, Shadabul Haque & Lisa M. Kaminskas. (2017) Polymer-drug conjugates as inhalable drug delivery systems: A review. Current Opinion in Colloid & Interface Science 31, pages 18-29.
Crossref
Crossref
Masatoshi Karashima, Noriyasu Sano, Syunsuke Yamamoto, Yuta Arai, Katsuhiko Yamamoto, Nobuyuki Amano & Yukihiro Ikeda. (2017) Enhanced pulmonary absorption of poorly soluble itraconazole by micronized cocrystal dry powder formulations. European Journal of Pharmaceutics and Biopharmaceutics 115, pages 65-72.
Crossref
Crossref
Aateka Patel, A. Woods, Yanira Riffo-Vasquez, Anna Babin-Morgan, Marie-Christine Jones, Stuart Jones, Kavitha Sunassee, Stephen Clark, Rafael T. M. de Rosales, Clive Page, Domenico Spina, Ben Forbes & Lea Ann Dailey. (2016) Lung inflammation does not affect the clearance kinetics of lipid nanocapsules following pulmonary administration. Journal of Controlled Release 235, pages 24-33.
Crossref
Crossref
Winston Ong, Pawel Nowak, Yen Cu, Lisa Schopf, James Bourassa, Elizabeth Enlow, Samuel M. Moskowitz & Hongming Chen. (2015) Sustained Pulmonary Delivery of a Water-Soluble Antibiotic Without Encapsulating Carriers. Pharmaceutical Research 33:3, pages 563-572.
Crossref
Crossref
Hae-Ok Byun, Young-Kyoung Lee, Jeong-Min Kim & Gyesoon Yoon. (2015) From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes. BMB Reports 48:10, pages 549-558.
Crossref
Crossref
Ewelina Hoffman, Abhinav Kumar, Varsha Kanabar, Matthew Arno, Lucas Preux, Val Millar, Clive Page, Helen Collins, Ian Mudway, Lea Ann Dailey & Ben Forbes. (2015)
In Vitro
Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines
. Molecular Pharmaceutics 12:8, pages 2675-2687.
Crossref
Crossref
Chris De Savi, Rhona J. Cox, Daniel J. WarnerAnthony R. CookMark R. DickinsonAmy McDonoughLouis C. MorrillBeth ParkerGlen AndrewsSimon S. YoungPeter S. GilmourRob RileyMatthew S. Dearman. (2014) Efficacious Inhaled PDE4 Inhibitors with Low Emetic Potential and Long Duration of Action for the Treatment of COPD. Journal of Medicinal Chemistry 57:11, pages 4661-4676.
Crossref
Crossref
Ben Forbes, Raegan O'Lone, Philippa Pribul Allen, Anthony Cahn, Chris Clarke, Mark Collinge, Lea Ann Dailey, Louise E. Donnelly, Joseph Dybowski, David Hassall, Deon Hildebrand, Rhys Jones, Joanne Kilgour, Jan Klapwijk, Curtis C. Maier, Tim McGovern, Kristen Nikula, Joel D. Parry, Matthew D. Reed, Ian Robinson, Lindsay Tomlinson & Alison Wolfreys. (2014) Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses. Advanced Drug Delivery Reviews 71, pages 15-33.
Crossref
Crossref
Kristen J. Nikula, Jeffrey E. McCartney, Timothy McGovern, Glen K. Miller, Marielle Odin, Michael V. Pino & Matthew D. Reed. (2013) STP Position Paper. Toxicologic Pathology 42:3, pages 472-486.
Crossref
Crossref
David J. Lewis, Thomas C. Williams & Steven L. Beck. (2014) Foamy macrophage responses in the rat lung following exposure to inhaled pharmaceuticals: a simple, pragmatic approach for inhaled drug development. Journal of Applied Toxicology 34:4, pages 319-331.
Crossref
Crossref
Erik Wahlström, Anna Ollerstam, Lena Sundius & Hui Zhang. (2013) Use of Lung Weight as Biomarker for Assessment of Lung Toxicity in Rat Inhalation Studies. Toxicologic Pathology 41:6, pages 902-912.
Crossref
Crossref
Jack R. Harkema, Kristen J. Nikula & Wanda M. Haschek. 2013. Haschek and Rousseaux's Handbook of Toxicologic Pathology. Haschek and Rousseaux's Handbook of Toxicologic Pathology
1935
2003
.
Christophe Duret, Nathalie Wauthoz, Thami Sebti, Francis Vanderbist & Karim Amighi. (2012) New Respirable and Fast Dissolving Itraconazole Dry Powder Composition for the Treatment of Invasive Pulmonary Aspergillosis. Pharmaceutical Research 29:10, pages 2845-2859.
Crossref
Crossref
Christophe Duret, Nathalie Wauthoz, Thami Sebti, Francis Vanderbist & Karim Amighi. (2012) Solid dispersions of itraconazole for inhalation with enhanced dissolution, solubility and dispersion properties. International Journal of Pharmaceutics 428:1-2, pages 103-113.
Crossref
Crossref