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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 8
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Clinical Pharmacokinetics and Metabolism

Prediction of drug concentration-time data in humans from animals: a comparison of three methods

Iftekhar MahmoodOffice of Blood Review & Research (OBRR), Center for Biologic Evaluation and Research, Food & Drug Administration, Rockville, MD, USACorrespondence[email protected]
&
Kosalaram GotetiClinical Pharmacology and DMPK, MedImmune LLC, Gaithersburg, MD, USA
Pages 756-765 | Received 15 Dec 2011, Accepted 19 Jan 2012, Published online: 24 Feb 2012

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Iftekhar Mahmood. (2013) Allometric scaling and prediction of concentration-time profiles of coagulation factors in humans from animals. Xenobiotica 43:9, pages 774-779.
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Iftekhar Mahmood. (2013) Prediction of drug concentration-time profiles of therapeutic proteins in humans from animals. Xenobiotica 43:2, pages 153-160.
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Articles from other publishers (4)

Masahiro Yahata, Yuji Ishii, Tetsuya Nakagawa, Takao Watanabe & Izuru Miyawaki. (2020) Applicability of the Øie‐Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase. Biopharmaceutics & Drug Disposition 41:4-5, pages 151-165.
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Guido Bocci, Esther K. Lee, Anthony J. Mutsaers & Urban Emmenegger. 2016. Animal Models for Human Cancer. Animal Models for Human Cancer 223 246 .
Jean W Lee. (2013) ADME of monoclonal antibody biotherapeutics: knowledge gaps and emerging tools. Bioanalysis 5:16, pages 2003-2014.
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Miroslav Dostalek, Iain Gardner, Brian M. Gurbaxani, Rachel H. Rose & Manoranjenni Chetty. (2013) Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies. Clinical Pharmacokinetics 52:2, pages 83-124.
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