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Xenobiotica
the fate of foreign compounds in biological systems
Volume 42, 2012 - Issue 10
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Animal Pharmacokinetics and Metabolism

Pharmacokinetic interaction between metoprolol and SP-8203 in rats: competitive inhibition for the metabolism of metoprolol by SP-8203 via hepatic CYP2D subfamily

Seung Yon HanCollege of Pharmacy, Dongguk University-Seoul, Seoul, South Korea
,
Insoo YoonCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
,
Young-Won ChinCollege of Pharmacy, Dongguk University-Seoul, Seoul, South Korea
,
Il Whan ChoCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea
,
Myung Gull LeeCentral Research Institute, Shin Poong Pharmaceutical Company, Ltd., Ansan, South Korea
&
Young Hee ChoiCollege of Pharmacy, Dongguk University-Seoul, Seoul, South KoreaCorrespondence[email protected]
Pages 1017-1027 | Received 13 Dec 2011, Accepted 30 Jan 2012, Published online: 09 May 2012

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Sang-Bum Kim, Hee Eun Kang, Hyun-Jong Cho, Yeong Shik Kim, Suk-Jae Chung, In-Soo Yoon & Dae-Duk Kim. (2016) Metabolic interactions of magnolol with cytochrome P450 enzymes: uncompetitive inhibition of CYP1A and competitive inhibition of CYP2C. Drug Development and Industrial Pharmacy 42:2, pages 263-269.
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