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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 6
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Topics in Xenobiochemistry

Contrasting toxicokinetic evaluations and interspecies pharmacokinetic scaling approaches for small molecules and biologics: applicability to biosimilar development

Elliot OffmanSchool of Pharmacy, University of Waterloo, Waterloo, Ontario, Canada
&
Andrea N. EdgintonSchool of Pharmacy, University of Waterloo, Waterloo, Ontario, CanadaCorrespondence[email protected]
Pages 561-569 | Received 13 Sep 2012, Accepted 23 Oct 2012, Published online: 17 Dec 2012

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Eva Germovsek, Ming Cheng & Craig Giragossian. (2021) Allometric scaling of therapeutic monoclonal antibodies in preclinical and clinical settings. mAbs 13:1.
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Articles from other publishers (5)

Katherine Dunnington, Natacha Benrimoh, Christine Brandquist, Nadia Cardillo-Marricco, Mike Di Spirito & Julie Grenier. 2018. Pharmacokinetics and Adverse Effects of Drugs - Mechanisms and Risks Factors. Pharmacokinetics and Adverse Effects of Drugs - Mechanisms and Risks Factors.
Elliot Offman, Colin Phipps & Andrea N. Edginton. (2016) Population physiologically-based pharmacokinetic model incorporating lymphatic uptake for a subcutaneously administered pegylated peptide. In Silico Pharmacology 4:1.
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Elliot Offman & Andrea N. Edginton. (2015) A PBPK workflow for first-in-human dose selection of a subcutaneously administered pegylated peptide. Journal of Pharmacokinetics and Pharmacodynamics 42:2, pages 135-150.
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O. V. Polekhina, N. V. Obraztsov, V. A. Petrunin & T. A. Vysotskaya. (2015) Interspecies Pharmacokinetics. 2. Analysis of the Structure of Interspecies Relationships Between Parameters of Drug Pharmacokinetics. Pharmaceutical Chemistry Journal 48:10, pages 635-639.
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O. V. Polekhina, N. V. Obraztsov, V. A. Petrunin & T. A. Vysotskaya. (2014) Interspecies Pharmacokinetics. 1. Allometric Scaling of Pharmacokinetic Parameters (a Review). Pharmaceutical Chemistry Journal 48:7, pages 421-429.
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