Citations (56)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Hyun-Jong Cho, Jin Woo Park, In-Soo Yoon & Dae-Duk Kim. (2014) Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake. International Journal of Nanomedicine 9, pages 495-504.
Read now
Read now
Hyun-Jong Cho, Ji-Eon Kim, Dae-Duk Kim & In-Soo Yoon. (2014) In vitro–in vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: principles and applications. Drug Development and Industrial Pharmacy 40:8, pages 989-998.
Read now
Read now
Articles from other publishers (54)
Jihoon Lee, Min-Koo Choi & Im-Sook Song. (2023) Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting. Pharmaceuticals 16:6, pages 802.
Crossref
Crossref
Mohd Asif, Farrukh Aqil, Fatmah Ali Alasmary, Amani salem almalki, Abdul Rahman Khan & Malik Nasibullah. (2023) Lewis base-catalyzed synthesis of highly functionalized spirooxindole-pyranopyrazoles and their in vitro anticancer studies. Medicinal Chemistry Research 32:5, pages 1001-1015.
Crossref
Crossref
Mohd Asif, Sahir Sultan Alvi, Tazeen Azaz, Abdul Rahman Khan, Bhoopendra Tiwari, Bilal Bin Hafeez & Malik Nasibullah. (2023) Novel Functionalized Spiro [Indoline-3,5′-pyrroline]-2,2′dione Derivatives: Synthesis, Characterization, Drug-Likeness, ADME, and Anticancer Potential. International Journal of Molecular Sciences 24:8, pages 7336.
Crossref
Crossref
Amal A. Sultan, Ghada A. Saad & Gamal M. El Maghraby. (2023) Permeation enhancers loaded bilosomes for improved intestinal absorption and cytotoxic activity of doxorubicin. International Journal of Pharmaceutics 630, pages 122427.
Crossref
Crossref
Seho Kweon, Yoo-Seong Jeong, Seung Woo Chung, Hanul Lee, Ha Kyeong Lee, Seong Jin Park, Jeong Uk Choi, Jooho Park, Suk-Jae Chung & Youngro Byun. (2022) Metronomic dose-finding approach in oral chemotherapy by experimentally-driven integrative mathematical modeling. Biomaterials 286, pages 121584.
Crossref
Crossref
Huikang Yang, Nianhua Wang, Ruimeng Yang, Liming Zhang & Xinqing Jiang. (2021) Folic Acid-Decorated β-Cyclodextrin-Based Poly(ε-caprolactone)-dextran Star Polymer with Disulfide Bond-Linker as Theranostic Nanoparticle for Tumor-Targeted MRI and Chemotherapy. Pharmaceutics 14:1, pages 52.
Crossref
Crossref
Ji-Min Kim, Seong-Wook Seo, Dong-Gyun Han, Hwayoung Yun & In-Soo Yoon. (2021) Assessment of Metabolic Interaction between Repaglinide and Quercetin via Mixed Inhibition in the Liver: In Vitro and In Vivo. Pharmaceutics 13:6, pages 782.
Crossref
Crossref
Muhammad Zakir, Ahmat Khurshid, Muhammad Iqbal Khan, Asma Khattak & Murad Ali Khan. (2020) The application of aluminium phthalocyanine AlPs-4-mediated photodynamic therapy against human soft tissue sarcoma (RMS) cell line. Journal of Porphyrins and Phthalocyanines 25:02, pages 102-119.
Crossref
Crossref
Dong-Gyun Han, Eunju Cha, Jeongmin Joo, Ji Sun Hwang, Sanghyun Kim, Taeuk Park, Yoo-Seong Jeong, Han-Joo Maeng, Sang-Bum Kim & In-Soo Yoon. (2021) Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects. Pharmaceutics 13:2, pages 175.
Crossref
Crossref
Duygu Durna Corum & Kamil Uney. (2020) Gender Differences in the Effect of Calcitriol on the Body Disposition and Excretion of Doxorubicin in Mice. European Journal of Drug Metabolism and Pharmacokinetics 45:5, pages 653-664.
Crossref
Crossref
Leandro Francisco Pippa, Milena Locci de Oliveira, Adriana Rocha, Jurandyr Moreira de Andrade & Vera Lucia Lanchote. (2020) Total, renal and hepatic clearances of doxorubicin and formation clearance of doxorubicinol in patients with breast cancer: Estimation of doxorubicin hepatic extraction ratio. Journal of Pharmaceutical and Biomedical Analysis 185, pages 113231.
Crossref
Crossref
Antonella Di Sotto, Silvia Di Giacomo, Elisabetta Rubini, Alberto Macone, Marco Gulli, Caterina Loredana Mammola, Margherita Eufemi, Romina Mancinelli & Gabriela Mazzanti. (2020) Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention. Cells 9:4, pages 858.
Crossref
Crossref
Jong Bong Lee, Simon Zhou, Manting Chiang, Xiaowei Zang, Tae Hwan Kim & Leonid Kagan. (2020) Interspecies prediction of pharmacokinetics and tissue distribution of doxorubicin by physiologically‐based pharmacokinetic modeling. Biopharmaceutics & Drug Disposition 41:4-5, pages 192-205.
Crossref
Crossref
Di Sotto, Irannejad, Eufemi, Mancinelli, Abete, Mammola, Altieri, Mazzanti & Di Giacomo. (2020) Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: an in Vitro and in Silico Study. International Journal of Molecular Sciences 21:2, pages 633.
Crossref
Crossref
Nipun Babu Varukattu, Raju Vivek, Chandrababu Rejeeth, Ramar Thangam, Thondhi Ponraj, Alok Sharma & Soundarapandian Kannan. (2020) Nanostructured pH-responsive biocompatible chitosan coated copper oxide nanoparticles: A polymeric smart intracellular delivery system for doxorubicin in breast cancer cells. Arabian Journal of Chemistry 13:1, pages 2276-2286.
Crossref
Crossref
Linxia Xiao, Yuqin Zhou, Xiangli Zhang, Yan Ding & Qingyong Li. (2019) Transporter-Targeted Bile Acid-Camptothecin Conjugate for Improved Oral Absorption. Chemical and Pharmaceutical Bulletin 67:10, pages 1082-1087.
Crossref
Crossref
Miao Wang, Da Wang, Changjiu Gao, Xianzhe Li, Luping Sha, Qiang Zhao, Huiyuan Gao & Zhaohua Wu. (2019) Pharmacokinetic and tissue distribution studies of cassane diterpenoids, in rats through an ultra‐high‐performance liquid chromatography–Q exactive hybrid quadrupole–Orbitrap high‐resolution accurate mass spectrometry. Biomedical Chromatography 33:10.
Crossref
Crossref
Junlong Liang, Qianwei Huang, Chenxiang Hua, Jinhua Hu, Biling Chen, Junmin Wan, Zhiwen Hu & Bing Wang. (2019) pH‐Responsive Nanoparticles Loaded with Graphene Quantum Dots and Doxorubicin for Intracellular Imaging, Drug Delivery and Efficient Cancer Therapy. ChemistrySelect 4:20, pages 6004-6012.
Crossref
Crossref
Andrew D. Wong, Luisa M. Russell, Moriah E. Katt & Peter C. Searson. (2018) Chemotherapeutic Drug Delivery and Quantitative Analysis of Proliferation, Apoptosis, and Migration in a Tissue-Engineered Three-Dimensional Microvessel Model of the Tumor Microenvironment. ACS Biomaterials Science & Engineering 5:2, pages 633-643.
Crossref
Crossref
Sally A. El-Zahaby, Yosra S.R. Elnaggar & Ossama Y. Abdallah. (2019) Reviewing two decades of nanomedicine implementations in targeted treatment and diagnosis of pancreatic cancer: An emphasis on state of art. Journal of Controlled Release 293, pages 21-35.
Crossref
Crossref
Takanori Akazawa, Shinpei Yoshida, Shuichi Ohnishi, Takushi Kanazu, Makoto Kawai & Koji Takahashi. (2018) Application of Intestinal Epithelial Cells Differentiated from Human Induced Pluripotent Stem Cells for Studies of Prodrug Hydrolysis and Drug Absorption in the Small Intestine. Drug Metabolism and Disposition 46:11, pages 1497-1506.
Crossref
Crossref
Seung Woo Chung, Gui Chul Kim, Seho Kweon, Hanul Lee, Jeong Uk Choi, Foyez Mahmud, Hyo Won Chang, Ji Won Kim, Woo-Chan Son, Sang Yoon Kim & Youngro Byun. (2018) Metronomic oral doxorubicin in combination of Chk1 inhibitor MK-8776 for p53-deficient breast cancer treatment. Biomaterials 182, pages 35-43.
Crossref
Crossref
Ivana Borišev, Jasminka Mrđanovic, Danijela Petrovic, Mariana Seke, Danica Jović, Branislava Srđenović, Natasa Latinovic & Aleksandar Djordjevic. (2018) Nanoformulations of doxorubicin: how far have we come and where do we go from here?. Nanotechnology 29:33, pages 332002.
Crossref
Crossref
Xu-zhao Li, Shuai-nan Zhang & Xu-yan Yang. (2017)
Combination of cheminformatics and bioinformatics to explore the chemical basis of the rhizomes and aerial parts of
Dioscorea nipponica
Makino
. Journal of Pharmacy and Pharmacology 69:12, pages 1846-1857.
Crossref
Crossref
Karolina Matyjaszczyk, Marta Kolonko, Anna Gonciarz-Dytman, Irena Oszczapowicz, Małgorzata Łukawska, Wojciech Jawień, Stefan Chlopicki & Maria Walczak. (2017) Effects of structural modification of the daunosamine moiety of anthracycline antibiotics on pKa values determined by capillary zone electrophoresis. Journal of Chromatography B 1060, pages 44-52.
Crossref
Crossref
Isra Dmour & Mutasem O. Taha. (2017) Novel nanoparticles based on chitosan-dicarboxylate conjugates via tandem ionotropic/covalent crosslinking with tripolyphosphate and subsequent evaluation as drug delivery vehicles. International Journal of Pharmaceutics 529:1-2, pages 15-31.
Crossref
Crossref
Samaa Alrushaid, Yunqi Zhao, Casey L. Sayre, Zaid H. Maayah, M. Laird Forrest, Sanjeewa N. Senadheera, Kevin Chaboyer, Hope D. Anderson, Ayman O. S. El-Kadi & Neal M. Davies. (2017) Mechanistically elucidating the in vitro safety and efficacy of a novel doxorubicin derivative. Drug Delivery and Translational Research 7:4, pages 582-597.
Crossref
Crossref
Marie Lund, Tonny Studsgaard Petersen & Kim Peder Dalhoff. (2017) Clinical Implications of P-Glycoprotein Modulation in Drug–Drug Interactions. Drugs 77:8, pages 859-883.
Crossref
Crossref
Ilse R. Dubbelboer, Elsa Lilienberg, Erik Sjögren & Hans Lennernäs. (2017) A Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin Disposition. Molecular Pharmaceutics 14:3, pages 686-698.
Crossref
Crossref
Shuai-nan Zhang, Xu-zhao Li & Xu-yan Yang. (2017) Drug-likeness prediction of chemical constituents isolated from Chinese materia medica Ciwujia. Journal of Ethnopharmacology 198, pages 131-138.
Crossref
Crossref
Gregory Ondieki, Makafui Nyagblordzro, Siambi Kikete, Rongjia Liang, Lili Wang & Xin He. (2017) Cytochrome P450 and P-Glycoprotein-Mediated Interactions Involving African Herbs Indicated for Common Noncommunicable Diseases. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-18.
Crossref
Crossref
Dong Shik Kim, Dong Wuk Kim, Kyeong Soo Kim, Jong Seo Choi, Youn Gee Seo, Yu Seok Youn, Kyung Taek Oh, Chul Soon Yong, Jong Oh Kim, Sung Giu Jin & Han-Gon Choi. (2016) Development of a novel l-sulpiride-loaded quaternary microcapsule: Effect of TPGS as an absorption enhancer on physicochemical characterization and oral bioavailability. Colloids and Surfaces B: Biointerfaces 147, pages 250-257.
Crossref
Crossref
Ankitkumar S. Jain, Vivek V. Dhawan, Bruno Sarmento & Mangal S. Nagarsenker. (2016) In Vitro and Ex Vivo Evaluations of Lipid Anti-Cancer Nanoformulations: Insights and Assessment of Bioavailability Enhancement. AAPS PharmSciTech 17:3, pages 553-571.
Crossref
Crossref
M.H. Shoja, Neetinkumar D. Reddy, Pawan G. Nayak, Subhankar Biswas, K.K. Srinivasan & C. Mallikarjuna Rao. (2016) In vitro mechanistic and in vivo anti-tumor studies of Glycosmis pentaphylla (Retz.) DC against breast cancer. Journal of Ethnopharmacology 186, pages 159-168.
Crossref
Crossref
Stefanie D. Krämer, Hélène E. Aschmann, Maja Hatibovic, Katharina F. Hermann, Claudia S. Neuhaus, Cyrill Brunner & Sara Belli. (2016) When barriers ignore the “rule-of-five”. Advanced Drug Delivery Reviews 101, pages 62-74.
Crossref
Crossref
Jae-Young Lee, Sang-Bum Kim, Jaemoo Chun, Kwang Ho Song, Yeong Shik Kim, Suk-Jae Chung, Hyun-Jong Cho, In-Soo Yoon & Dae-Duk Kim. (2016)
High body clearance and low oral bioavailability of alantolactone, isolated from
Inula helenium
, in rats: extensive hepatic metabolism and low stability in gastrointestinal fluids
. Biopharmaceutics & Drug Disposition 37:3, pages 156-167.
Crossref
Crossref
Mengying Hu, Yurun Shen, Lu Zhang & Liyan Qiu. (2016) Polymersomes via Self-Assembly of Amphiphilic β-Cyclodextrin-Centered Triarm Star Polymers for Enhanced Oral Bioavailability of Water-Soluble Chemotherapeutics. Biomacromolecules 17:3, pages 1026-1039.
Crossref
Crossref
Amal Al-Saraf, René Holm & Carsten Uhd Nielsen. (2016) Tween 20 increases intestinal transport of doxorubicin in vitro but not in vivo. International Journal of Pharmaceutics 498:1-2, pages 66-69.
Crossref
Crossref
Ki Taek Kim, Jae-Young Lee, Ju-Hwan Park, Min Hwan Kim, Ji-Su Kim, Hyeon-Jong Shin, Naewon Kang, Hyun-Jong Cho, In-Soo Yoon & Dae-Duk Kim. (2016) Development of HPLC Method for the Determination of Buspirone in Rat Plasma Using Fluorescence Detection and Its Application to a Pharmacokinetic Study. CHEMICAL & PHARMACEUTICAL BULLETIN Chemical and Pharmaceutical Bulletin 64:11, pages 1582-1588.
Crossref
Crossref
Sang-Bum Kim, Hyun-Jong Cho, Yeong Shik Kim, Dae-Duk Kim & In-Soo Yoon. (2015)
Modulation of Cytochrome P450 Activity by 18
β
-Glycyrrhetic Acid and its Consequence on Buspirone Pharmacokinetics in Rats
. Phytotherapy Research 29:8, pages 1188-1194.
Crossref
Crossref
In-Soo Yoon, Jun-Hyeng Son, Sang-Bum Kim, Min-Koo Choi & Han-Joo Maeng. (2015) Effects of 1α,25-Dihydroxyvitamin D<sub>3</sub> on Intestinal Absorption and Disposition of Adefovir Dipivoxil and Its Metabolite, Adefovir, in Rats. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 38:11, pages 1732-1737.
Crossref
Crossref
Hyun-Jong Cho & In-Soo Yoon. (2015) Pharmacokinetic Interactions of Herbs with Cytochrome P450 and P-Glycoprotein. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-10.
Crossref
Crossref
Quanlei Zhu, Wenyi Song, Dengning Xia, Weiwei Fan, Miaorong Yu, Shiyan Guo, Chunliu Zhu & Yong Gan. (2015)
A poly-
l
-glutamic acid functionalized nanocomplex for improved oral drug absorption
. Journal of Materials Chemistry B 3:43, pages 8508-8517.
Crossref
Crossref
Benjamin Wuyts, Danny Riethorst, Joachim Brouwers, Jan Tack, Pieter Annaert & Patrick Augustijns. (2015) Evaluation of fasted and fed state simulated and human intestinal fluids as solvent system in the Ussing chambers model to explore food effects on intestinal permeability. International Journal of Pharmaceutics 478:2, pages 736-744.
Crossref
Crossref
Benjamin Wuyts, Danny Riethorst, Joachim Brouwers, Jan Tack, Pieter Annaert & Patrick Augustijns. (2015) Evaluation of fasted state human intestinal fluid as apical solvent system in the Caco-2 absorption model and comparison with FaSSIF. European Journal of Pharmaceutical Sciences 67, pages 126-135.
Crossref
Crossref
Ji-Eun Chang, In-Soo Yoon, Ping-Li Sun, Eunjue Yi, Sanghoon Jheon & Chang-Koo Shim. (2014) Anticancer efficacy of photodynamic therapy with hematoporphyrin-modified, doxorubicin-loaded nanoparticles in liver cancer. Journal of Photochemistry and Photobiology B: Biology 140, pages 49-56.
Crossref
Crossref
Mariana F.C. Cardoso, Patrícia C. Rodrigues, Maria Eduarda I.M. Oliveira, Ivson L. Gama, Illana M.C.B. da Silva, Isabela O. Santos, David R. Rocha, Rosa T. Pinho, Vitor F. Ferreira, Maria Cecília B.V. de Souza, Fernando de C. da Silva & Floriano Paes Silva-Jr. (2014) Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines. European Journal of Medicinal Chemistry 84, pages 708-717.
Crossref
Crossref
Lisa M. Kaminskas, Victoria M. McLeod, Gemma M. Ryan, Brian D. Kelly, John M. Haynes, Mark Williamson, Neeranat Thienthong, David J. Owen & Christopher J.H. Porter. (2014) Pulmonary administration of a doxorubicin-conjugated dendrimer enhances drug exposure to lung metastases and improves cancer therapy. Journal of Controlled Release 183, pages 18-26.
Crossref
Crossref
Kyoung Song, In-Soo Yoon, Nam Ah Kim, Dong-Hwan Kim, Jongmin Lee, Hee Jung Lee, Saehyung Lee, Sunghyun Choi, Min-Koo Choi, Ha Hyung Kim, Seong Hoon Jeong, Woo Sung Son, Dae-Duk Kim & Young Kee Shin. (2014) Glycoengineering of Interferon-β 1a Improves Its Biophysical and Pharmacokinetic Properties. PLoS ONE 9:5, pages e96967.
Crossref
Crossref
Ilse R Dubbelboer, Elsa Lilienberg, Emelie Ahnfelt, Erik Sjögren, Niklas Axén & & Hans Lennernäs. (2014) Treatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systems. Therapeutic Delivery 5:4, pages 447-466.
Crossref
Crossref
Ji-Eon Kim, In-Soo Yoon, Hyun-Jong Cho, Dong-Hwan Kim, Young-Hee Choi & Dae-Duk Kim. (2014) Emulsion-based colloidal nanosystems for oral delivery of doxorubicin: Improved intestinal paracellular absorption and alleviated cardiotoxicity. International Journal of Pharmaceutics 464:1-2, pages 117-126.
Crossref
Crossref
Hyun-Jong Cho, Jongsuk Oh, Moon-Ki Choo, Jong-In Ha, Youmie Park & Han-Joo Maeng. (2014) Chondroitin sulfate-capped gold nanoparticles for the oral delivery of insulin. International Journal of Biological Macromolecules 63, pages 15-20.
Crossref
Crossref
Elsa Lilienberg, Charlotte Ebeling Barbier, Rickard Nyman, Mikael Hedeland, Ulf Bondesson, Niklas Axén & Hans Lennernäs. (2013) Investigation of Hepatobiliary Disposition of Doxorubicin Following Intrahepatic Delivery of Different Dosage Forms. Molecular Pharmaceutics 11:1, pages 131-144.
Crossref
Crossref
Goo Yoon, Jin Woo Park & In-Soo Yoon. (2013) Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs): recent advances in drug delivery. Journal of Pharmaceutical Investigation 43:5, pages 353-362.
Crossref
Crossref