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Xenobiotica
the fate of foreign compounds in biological systems
Volume 43, 2013 - Issue 9
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Research Article

Time-dependent changes in hepatic and intestinal induction of cytochrome P450 3A after administration of dexamethasone to rats

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Pages 765-773 | Received 27 Oct 2012, Accepted 19 Dec 2012, Published online: 23 Jan 2013

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Poonam Giri, Prashant Delvadia, Laxmikant Gupta, Nirmal Patel, Priyal Trivedi, Krishna Lad, Hiren M. Patel & Nuggehally R. Srinivas. (2018) Consequences of daily corticosteroid dosing with or without pre-treatment with quinidine on the in vivo cytochrome P450 2D (CYP2D) enzyme in rats: effect on O-demethylation activity of dextromethorphan and expression levels of CYP2D1 mRNA. Xenobiotica 48:1, pages 1-10.
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María Laura Maté, Mariana Ballent, Karen Larsen, Adrian Lifschitz, Carlos Lanusse & Guillermo Virkel. (2015) Gene expression and enzyme function of two cytochrome P450 3A isoenzymes in rat and cattle precision cut liver slices. Xenobiotica 45:7, pages 563-570.
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Articles from other publishers (7)

Min-Chang Kim & Young-Joo Lee. (2022) Analysis of Time-Dependent Pharmacokinetics Using In Vitro–In Vivo Extrapolation and Physiologically Based Pharmacokinetic Modeling. Pharmaceutics 14:12, pages 2562.
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Qing-yu Yao, Jian Li, Rong Chen, Ye Yao, Jun-sheng Xue, Wen-jun Chen, Wei Lu & Tian-yan Zhou. (2019) Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer. Acta Pharmacologica Sinica 40:12, pages 1596-1602.
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Paudel, Shrestha, Cho, Shrestha, Kim, Lee, Kim, Jeong, Lee & Lee. (2019) Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators. Pharmaceutics 11:9, pages 479.
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Swan Lin, Dana J. Nickens, Maulik Patel, Keith D. Wilner & Weiwei Tan. (2019) Clinical implications of an analysis of pharmacokinetics of crizotinib coadministered with dexamethasone in patients with non-small cell lung cancer. Cancer Chemotherapy and Pharmacology 84:1, pages 203-211.
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Jian Li, Rong Chen, Qing-yu Yao, Sheng-jun Liu, Xiu-yun Tian, Chun-yi Hao, Wei Lu & Tian-yan Zhou. (2017) Time-dependent pharmacokinetics of dexamethasone and its efficacy in human breast cancer xenograft mice: a semi-mechanism-based pharmacokinetic/pharmacodynamic model. Acta Pharmacologica Sinica 39:3, pages 472-481.
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Jian Li, Qing-yu Yao, Jun-sheng Xue, Li-jie Wang, Yin Yuan, Xiu-yun Tian, Hong Su, Si-yuan Wang, Wen-jun Chen, Wei Lu & Tian-yan Zhou. (2017) Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer. Acta Pharmacologica Sinica 38:9, pages 1282-1296.
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Marzia A. Locatelli, Philippe Aftimos, E. Claire Dees, Patricia M. LoRusso, Mark D. Pegram, Ahmad Awada, Bo Huang, Rossano Cesari, Yuqiu Jiang, M. Naveed Shaik, Kenneth A. Kern & Giuseppe Curigliano. (2016) Phase I study of the gamma secretase inhibitor PF-03084014 in combination with docetaxel in patients with advanced triple-negative breast cancer. Oncotarget 8:2, pages 2320-2328.
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