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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 1
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Research Article

Drug interactions of diclofenac and its oxidative metabolite with human liver microsomal cytochrome P450 1A2-dependent drug oxidation

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Pages 10-16 | Received 24 Apr 2013, Accepted 14 May 2013, Published online: 18 Jun 2013

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Shuting Wang, Xiange Tang, Tingting Yang, Jiong Xu, Jiaxin Zhang, Xiaodong Liu & Li Liu. (2019) Predicted contributions of cytochrome P450s to drug metabolism in human liver microsomes using relative activity factor were dependent on probes. Xenobiotica 49:2, pages 161-168.
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Articles from other publishers (10)

Dorota Kowalska, Jakub Maculewicz, Piotr Stepnowski & Joanna Dołżonek. (2021) Interaction of pharmaceutical metabolites with blood proteins and membrane lipids in the view of bioconcentration: A preliminary study based on in vitro assessment. Science of The Total Environment 783, pages 146987.
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S. M. Kamrul Hasan, Ran Li, Yichao Wang, Narendra Reddy, Wanshuang Liu, Yiping Qiu & Qiuran Jiang. (2019) Sustained Local Delivery of Diclofenac from Three-Dimensional Ultrafine Fibrous Protein Scaffolds with Ultrahigh Drug Loading Capacity. Nanomaterials 9:7, pages 918.
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Norie Murayama, Kanako Yajima, Mikiko Hikawa, Kanami Shimura, Yu Ishii, Masaki Takada, Yasuhiro Uno, Masahiro Utoh, Kazuhide Iwasaki & Hiroshi Yamazaki. (2018) Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies. Biopharmaceutics & Drug Disposition 39:2, pages 116-121.
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Chii Chii Chew, Salby Ng, Yun Lee Chee, Teng Wai Koo, Ming Hui Liew, Evelyn Li-Ching Chee, Pilar Modamio, Cecilia Fernández, Eduardo L. Mariño & Ignacio Segarra. (2017) Diclofenac sex-divergent drug-drug interaction with Sunitinib: pharmacokinetics and tissue distribution in male and female mice. Investigational New Drugs 35:4, pages 399-411.
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Siok Yean Tan, Mei Mei Wong, Angela Lu Wun Tiew, Yai Wen Choo, Suat Hun Lim, Ing Hong Ooi, Pilar Modamio, Cecilia Fernández, Eduardo L. Mariño & Ignacio Segarra. (2016) Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice. Cancer Chemotherapy and Pharmacology 78:4, pages 709-718.
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Qiushi Xie, Yang Chen, Fei Liu, Zeyu Zhong, Kaijing Zhao, Zhaoli Ling, Fan Wang, Xiange Tang, Zhongjian Wang, Li Liu & Xiaodong Liu. (2016) Interspecies differences in metabolism of deoxypodophyllotoxin in hepatic microsomes from human, monkey, rat, mouse and dog. Drug Metabolism and Pharmacokinetics 31:4, pages 314-322.
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Anthony Zulli, Renee M. Smith, Peter Kubatka, Jan Novak, Yoshio Uehara, Hayley Loftus, Tawar Qaradakhi, Miroslav Pohanka, Nazarii Kobyliak, Angela Zagatina, Jan Klimas, Alan Hayes, Giampiero La Rocca, Miroslav Soucek & Peter Kruzliak. (2016) Caffeine and cardiovascular diseases: critical review of current research. European Journal of Nutrition 55:4, pages 1331-1343.
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Lian-Hua Xu, Haruo Ikeda, Ling Liu, Takatoshi Arakawa, Takayoshi Wakagi, Hirofumi Shoun & Shinya Fushinobu. (2014) Structural basis for the 4′-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenase. Applied Microbiology and Biotechnology 99:7, pages 3081-3091.
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Yasuhiro Uno, Akinori Matsushita, Mitsunori Shukuya, Yasuka Matsumoto, Norie Murayama & Hiroshi Yamazaki. (2014) CYP2C19 polymorphisms account for inter-individual variability of drug metabolism in cynomolgus macaques. Biochemical Pharmacology 91:2, pages 242-248.
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Katsuhiro Ohyama, Makiko Shimizu & Hiroshi Yamazaki. (2014) A Survey of Adverse Effects and Risk Factors for Topical Dermatological Application of Diclofenac. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) 40:5, pages 310-316.
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