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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 2
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Review Article

Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications

Nico ScheerTaconicArtemis, Neurather Ring 1, Koeln 51063, GermanyCorrespondence[email protected]
&
C. Roland WolfMedical Research Institute, Ninewells Hospital and Medical School, University of Dundee DundeeUK
Pages 96-108 | Received 07 May 2013, Accepted 12 Jun 2013, Published online: 11 Jul 2013

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Donna A. Volpe & Hisham Qosa. (2018) Challenges with the precise prediction of ABC-transporter interactions for improved drug discovery. Expert Opinion on Drug Discovery 13:8, pages 697-707.
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Sanil Bhatia, Svenja Daschkey, Franziska Lang, Arndt Borkhardt & Julia Hauer. (2016) Mouse models for pre-clinical drug testing in leukemia. Expert Opinion on Drug Discovery 11:11, pages 1081-1091.
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Aaron C Gerlach & Brett M Antonio. (2015) Validation of ion channel targets. Channels 9:6, pages 376-379.
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Frank J Gonzalez, Zhong-Ze Fang & Xiaochao Ma. (2015) Transgenic mice and metabolomics for study of hepatic xenobiotic metabolism and toxicity. Expert Opinion on Drug Metabolism & Toxicology 11:6, pages 869-881.
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Swati Jaiswal, Abhisheak Sharma, Mahendra Shukla, Kalpesh Vaghasiya, Nagarjun Rangaraj & Jawahar Lal. (2014) Novel pre-clinical methodologies for pharmacokinetic drug–drug interaction studies: spotlight on “humanized” animal models. Drug Metabolism Reviews 46:4, pages 475-493.
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Min Zhang, Chong-sheng Peng & Xiao-bo Li. (2015) In Vivo and In Vitro Metabolites from the Main Diester and Monoester Diterpenoid Alkaloids in a Traditional Chinese Herb, the Aconitum Species . Evidence-Based Complementary and Alternative Medicine 2015, pages 1-23.
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Pavel Soucek. 2014. Encyclopedia of Cancer. Encyclopedia of Cancer 1 5 .
Andrew Owen & Paul Curley. 2014. Humanized Mice for HIV Research. Humanized Mice for HIV Research 339 360 .

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