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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 8
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Xenobiotic Transporters

P-glycoprotein (P-gp)-mediated efflux limits intestinal absorption of the Hsp90 inhibitor SNX-2112 in rats

Hongming LiuDivision of Pharmaceutics, College of Pharmacy, Jinan University GuangzhouPeople’s Republic of China
,
Hua SunDivision of Pharmaceutics, College of Pharmacy, Jinan University GuangzhouPeople’s Republic of China
,
Zhufeng WuDivision of Pharmaceutics, College of Pharmacy, Jinan University GuangzhouPeople’s Republic of China
,
Xingwang ZhangDivision of Pharmaceutics, College of Pharmacy, Jinan University GuangzhouPeople’s Republic of China
&
Baojian WuDivision of Pharmaceutics, College of Pharmacy, Jinan University GuangzhouPeople’s Republic of ChinaCorrespondence[email protected]
Pages 763-768 | Received 14 Jan 2014, Accepted 04 Feb 2014, Published online: 20 Feb 2014

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Hua Sun, Hui Liu, Huinan Zhao, Ying Wang, Yao-lan Li, Wen-cai Ye & Baojian Wu. (2017) Pharmacokinetic characterization of anhuienoside C and its deglycosylated metabolites in rats. Xenobiotica 47:10, pages 885-893.
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Dong Dong, Xiao Wang, Huailing Wang, Xingwang Zhang, Yifei Wang & Baojian Wu. (2015) Elucidating the in vivo fate of nanocrystals using a physiologically based pharmacokinetic model: a case study with the anticancer agent SNX-2112. International Journal of Nanomedicine 10, pages 2521-2535.
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Huinan Zhao, Hui Liu, Zhiguo Ma, Ying Wang, Yao-lan Li, Wen-Cai Ye & Baojian Wu. (2015) Metabolite profiling of anhuienoside C by rat intestinal bacteria using the LC–MS metabolomic approach. Xenobiotica 45:3, pages 189-196.
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Articles from other publishers (5)

Christine M. Madla, Yujia Qin, Francesca K. H. Gavins, Jing Liu, Liu Dou, Mine Orlu, Sudaxshina Murdan, Yang Mai & Abdul W. Basit. (2022) Sex Differences in Intestinal P-Glycoprotein Expression in Wistar versus Sprague Dawley Rats. Pharmaceutics 14:5, pages 1030.
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Kei Suzuki, Kazuhiro Taniyama, Takao Aoyama & Yoshiaki Watanabe. (2020) Evaluation of the Role of P-glycoprotein (P-gp)-Mediated Efflux in the Intestinal Absorption of Common Substrates with Elacridar, a P-gp Inhibitor, in Rats. European Journal of Drug Metabolism and Pharmacokinetics 45:3, pages 385-392.
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Li Li, Lei Wang, Qi-Dong You & Xiao-Li Xu. (2019) Heat Shock Protein 90 Inhibitors: An Update on Achievements, Challenges, and Future Directions. Journal of Medicinal Chemistry 63:5, pages 1798-1822.
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Daniela V. Giacone, Vanessa F.M. Carvalho, Soraia K.P. Costa & Luciana B. Lopes. (2018) Evidence That P-glycoprotein Inhibitor (Elacridar)-Loaded Nanocarriers Improve Epidermal Targeting of an Anticancer Drug via Absorptive Cutaneous Transporters Inhibition. Journal of Pharmaceutical Sciences 107:2, pages 698-705.
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Ankit K. Rochani, Aswathy Ravindran Girija, Ankita Borah, Toru Maekawa & D. Sakthi Kumar. (2016) Heat-Shock Protein 90–Targeted Nano Anticancer Therapy. Journal of Pharmaceutical Sciences 105:4, pages 1454-1466.
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