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Xenobiotica
the fate of foreign compounds in biological systems
Volume 44, 2014 - Issue 8
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Research Article

Glucuronidation of aurantio-obtusin: identification of human UDP-glucuronosyltransferases and species differences

Bao-Li MiPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
,
Qi SunResearch and Development Department, JiLin Aodong Medicine Industry Group Co., Ltd. DunhuaChina
,
Yan-Qing QuThyroid Surgery, Yantaishan Hospital, Yantai ShandongChina
,
Xiao-Xu GaoPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
,
Zhen-Wen YuPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
,
Guang-Bo GeLaboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences DalianChina
,
Shan-Shan CaiPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
,
Jie ZhangPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
,
Yan-Chao ZhengPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChina
&
Zhen-Qiu ZhangPharmaceutical College, Liaoning University of Traditional Chinese Medicine DalianChinaCorrespondence[email protected]
 show all
Pages 716-721 | Received 22 Jan 2014, Accepted 14 Feb 2014, Published online: 11 Mar 2014

Citations (6)

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Lina Shan, Xianbao Shi, Tingting Hu, Jiayin Hu, Zhe Guo, Yonggui Song, Dan Su & Xiaoyong Zhang. (2022) In vitro differences in toddalolactone metabolism in various species and its effect on cytochrome P450 expression. Pharmaceutical Biology 60:1, pages 1591-1605.
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Articles from other publishers (5)

Manjiang Hu, Li Lin, Jun Liu, Yizhou Zhong, Boxuan Liang, Yuji Huang, Zhiming Li, Xi Lin, Bo Wang, Bingli Zhang, Hao Meng, Rongyi Ye, Jiaxin Du, Mingzhu Dai, Yi Peng, Hongqun Li, Qinghong Wu, Hongbin Gao, Xingfen Yang & Zhenlie Huang. (2022) Aurantio-obtusin induces hepatotoxicity through activation of NLRP3 inflammasome signaling. Toxicology Letters 354, pages 1-13.
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Longlong Xu, Zhuo Zhang, Feiran Hao, Wei Zhou, Xianglin Tang & Yue Gao. (2021) A comparative study of aurantio-obtusin metabolism in normal and liver-injured rats by ultra performance liquid chromatography quadrupole time-of-flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 196, pages 113896.
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Hu Tingting, Shi Xianbao, Jiayin Hu & Yang Jingming. (2021) Species Difference of Asarinin Metabolism in vitro and its Effect on the Activity of Cytochrome P450 Enzymes. Pharmacognosy Magazine 17:76, pages 759.
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Shun-Li Xiao, Liang-Jun Guan, Ren-Feng Jiang, Xiang-Gen Wang, Xing Li & Wei Cai. (2020) The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin. Current Drug Metabolism 21:12, pages 960-968.
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Fanxing Meng, Yan Li, Guiyuan He, Guangbo Ge & Shumin Liu. (2017) Identification of human UDP-glucuronosyltransferase isoforms involved in the isofraxidin glucuronidation and assessment of the species differences of the reaction. Fitoterapia 117, pages 118-125.
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