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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 2
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Research Article

In vitro and in vivo metabolism of 14C-AZ11, a novel inhibitor of bacterial DNA gyrase/type II topoisomerase

Jian GuoDepartment of DMPK and Correspondence[email protected] [email protected]
,
Camil JoubranDepartment of Chemistry, Infection Innovative Medicine, AstraZeneca Pharmaceuticals, Waltham, MA, USA
,
Ricardo A. Luzietti Jr.Department of DMPK and
,
Fei ZhouDepartment of Chemistry, Infection Innovative Medicine, AstraZeneca Pharmaceuticals, Waltham, MA, USA
,
Gregory S. BasarabDepartment of Chemistry, Infection Innovative Medicine, AstraZeneca Pharmaceuticals, Waltham, MA, USA
&
Karthick VishwanathanDepartment of DMPK and
Pages 158-170 | Received 15 Jul 2014, Accepted 05 Aug 2014, Published online: 21 Aug 2014

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Jian Guo, Camil Joubran, Ricardo A. Luzietti$suffix/text()$suffix/text(), Gregory S. Basarab, Scott W. Grimm & Karthick Vishwanathan. (2017) Absorption, distribution, metabolism and elimination of 14C-ETX0914, a novel inhibitor of bacterial type-II topoisomerases in rodents. Xenobiotica 47:1, pages 31-49.
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Articles from other publishers (2)

Akram Bagherinejad & Abdolali Alizadeh. (2022) A review of the synthetic strategies toward spirobarbiturate-fused 3- to 7-membered rings. Organic & Biomolecular Chemistry 20:36, pages 7188-7215.
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Hong-Wu Zhao, Ning-Ning Feng, Jia-Ming Guo, Juan Du, Wan-Qiu Ding, Li-Ru Wang & Xiu-Qing Song. (2018) Diastereoselective and Enantioselective Synthesis of Barbiturate-Fused Spirotetrahydroquinolines via Chiral Palladium(0)/Ligand Complex Catalyzed [4 + 2] Cycloaddition of Vinyl Benzoxazinanones with Barbiturate-Based Olefins. The Journal of Organic Chemistry 83:16, pages 9291-9299.
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