Citations (30)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Gabriel Tao, Junqing Huang, Bhagavatula Moorthy, Cathryn Wang, Ming Hu, Song Gao & Romi Ghose. (2020) Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity. Expert Opinion on Drug Metabolism & Toxicology 16:11, pages 1109-1124.
Read now
Read now
Ludwik Gorczyca & Lauren M. Aleksunes. (2020) Transcription factor-mediated regulation of the BCRP/ABCG2 efflux transporter: a review across tissues and species. Expert Opinion on Drug Metabolism & Toxicology 16:3, pages 239-253.
Read now
Read now
David E. Amacher. (2016) The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptors. Expert Opinion on Drug Metabolism & Toxicology 12:12, pages 1463-1477.
Read now
Read now
Zdenek Dvorak. (2016) Opportunities and challenges in using human hepatocytes in cytochromes P450 induction assays. Expert Opinion on Drug Metabolism & Toxicology 12:2, pages 169-174.
Read now
Read now
Articles from other publishers (26)
Anne T. Nies, Elke Schaeffeler & Matthias Schwab. (2022) Hepatic solute carrier transporters and drug therapy: Regulation of expression and impact of genetic variation. Pharmacology & Therapeutics 238, pages 108268.
Crossref
Crossref
Anna Zerdoug, Marc Le Vée, Shotaro Uehara, Béatrice Lopez, Christophe Chesné, Hiroshi Suemizu & Olivier Fardel. (2022) Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives. European Journal of Drug Metabolism and Pharmacokinetics 47:5, pages 621-637.
Crossref
Crossref
Elise Lelou, Anne Corlu, Nicolas Nesseler, Claudine Rauch, Yannick Mallédant, Philippe Seguin & Caroline Aninat. (2022) The Role of Catecholamines in Pathophysiological Liver Processes. Cells 11:6, pages 1021.
Crossref
Crossref
L. Ward, J. Wilcock & Philip Butler. 2022. The ADME Encyclopedia. The ADME Encyclopedia
368
379
.
Chase P. Monckton, Aidan Brougham‐Cook, Kerim B. Kaylan, Gregory H. Underhill & Salman R. Khetani. (2021) Elucidating Extracellular Matrix and Stiffness Control of Primary Human Hepatocyte Phenotype via Cell Microarrays. Advanced Materials Interfaces 8:22, pages 2101284.
Crossref
Crossref
Naji Said Aboud Hadi, Ezgi Eyluel Bankoglu, Lea Schott, Eva Leopoldsberger, Vanessa Ramge, Olaf Kelber, Hartwig Sievers & Helga Stopper. (2021) Genotoxicity of selected pyrrolizidine alkaloids in human hepatoma cell lines HepG2 and Huh6. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 861-862, pages 503305.
Crossref
Crossref
L. Ward, J. Wilcock & P. Butler. 2021. The ADME Encyclopedia. The ADME Encyclopedia
1
12
.
Clarissa Feltrin, Ingrid Vicente Farias, Louis Pergaud Sandjo, Flávio Henrique Reginatto & Cláudia Maria Oliveira Simões. (2020) Effects of Standardized Medicinal Plant Extracts on Drug Metabolism Mediated by CYP3A4 and CYP2D6 Enzymes. Chemical Research in Toxicology 33:9, pages 2408-2419.
Crossref
Crossref
Michele Protti, Roberto Mandrioli, Camilla Marasca, Andrea Cavalli, Alessandro Serretti & Laura Mercolini. (2020) New‐generation, non‐SSRI antidepressants: Drug‐drug interactions and therapeutic drug monitoring. Part 2: NaSSAs, NRIs, SNDRIs, MASSAs, NDRIs, and others. Medicinal Research Reviews 40:5, pages 1794-1832.
Crossref
Crossref
Katsuaki Ito, Noora Sjöstedt, Melina M. Malinen, Cen Guo & Kim L.R. Brouwer. (2020) Hepatic Transporter Alterations by Nuclear Receptor Agonist T0901317 in Sandwich-Cultured Human Hepatocytes: Proteomic Analysis and PBPK Modeling to Evaluate Drug-Drug Interaction Risk. Journal of Pharmacology and Experimental Therapeutics 373:2, pages 261-268.
Crossref
Crossref
A. David Rodrigues, Yurong Lai, Hong Shen, Manthena V.S. Varma, Andrew Rowland & Stefan Oswald. (2020) Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?. Drug Metabolism and Disposition 48:3, pages 205-216.
Crossref
Crossref
Naixing Zhang, Lei Ji, Zhixuan Chen, Lin An, Decheng Ren, Yan Bi, Zhenming Guo, Ruixue Yuan, Fan Yuan, Zaiquan Dong, Li Yin, Xueli Sun, Fengping Yang, Xingwang Li, Tao Yu, Lin He, Lei Shi & Guang He. (2020) No association between CYP2C19 genetic polymorphism with treatment remission to antidepressant venlafaxine in Han Chinese population. Psychiatric Genetics 30:1, pages 30-33.
Crossref
Crossref
Petar D. Petrov, Leonor Fernández-Murga, Isabel Conde, Teresa Martínez-Sena, Carla Guzmán, José Vicente Castell & Ramiro Jover. (2020) Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes. Archives of Toxicology 94:2, pages 589-607.
Crossref
Crossref
Clarissa Feltrin & Cláudia Maria Oliveira Simões. (2019) Reviewing the mechanisms of natural product-drug interactions involving efflux transporters and metabolic enzymes. Chemico-Biological Interactions 314, pages 108825.
Crossref
Crossref
Bryan Mackowiak, Linhao Li, Caitlin Lynch, Andrew Ziman, Scott Heyward, Menghang Xia & Hongbing Wang. (2019) High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis. Biochemical Pharmacology 168, pages 224-236.
Crossref
Crossref
Clarissa Feltrin, Paula Freire Brambila & Cláudia Maria Oliveira Simões. (2019) Development of Caco-2 cells-based gene reporter assays and evaluation of herb-drug interactions involving CYP3A4 and CYP2D6 gene expression. Chemico-Biological Interactions 303, pages 79-89.
Crossref
Crossref
Yuhao Zhu, Naixing Zhang, Decheng Ren, Yan Bi, Fei Xu, Weibo Niu, Qianqian Sun, Zhenming Guo, Ruixue Yuan, Fan Yuan, Xi Wu, Yanfei Cao, Fengping Yang, Lu Wang, Li Du, Weidong Li, Yifeng Xu, Xingwang Li, Liping Zhu, Lin He, Lei Shi, Guang He & Tao Yu. (2019) CYP1A2 Genetic Polymorphism Is Associated With Treatment Remission to Antidepressant Venlafaxine in Han Chinese Population. Clinical Neuropharmacology 42:2, pages 32-36.
Crossref
Crossref
Hong-Zhuo SHI, Wen-Qiang CHANG, Ming ZHANG & Hong-Xiang LOU. (2019) Two natural molecules preferentially inhibit azole-resistant Candida albicans with MDR1 hyperactivation. Chinese Journal of Natural Medicines 17:3, pages 209-217.
Crossref
Crossref
Jamie E. Moscovitz, Amit S. Kalgutkar, Kelly Nulick, Nathaniel Johnson, Zhiwu Lin, Theunis C. Goosen & Yan Weng. (2018) Establishing Transcriptional Signatures to Differentiate PXR-, CAR-, and AhR-Mediated Regulation of Drug Metabolism and Transport Genes in Cryopreserved Human Hepatocytes. Journal of Pharmacology and Experimental Therapeutics 365:2, pages 262-271.
Crossref
Crossref
Caroline MacLean, Frederik Weiß, Oliver Poetz & Thomas Ebner. (2017) Concept: The Use of Targeted Immunoaffinity Proteomics for Routine Assessment of In Vitro Enzyme Induction. Journal of Pharmaceutical Sciences 106:12, pages 3453-3457.
Crossref
Crossref
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, Joshua G. Dekeyser, Odette A. Fahmi, Jane R. Kenny, Heidi Einolf, Michael Mohutsky, Magalie Pardon, Y. Amy Siu, Liangfu Chen, Michael Sinz, Barry Jones, Robert Walsky, Shannon Dallas, Suresh K. Balani, George Zhang, David Buckley & Donald Tweedie. (2017) Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control. Drug Metabolism and Disposition 45:10, pages 1049-1059.
Crossref
Crossref
Rhishikesh Thakare, Hongying Gao, Rachel E. Kosa, Yi-An Bi, Manthena V. S. Varma, Matthew A. Cerny, Raman Sharma, Max Kuhn, Bingshou Huang, Yiping Liu, Aijia Yu, Gregory S. Walker, Mark Niosi, Larry Tremaine, Yazen Alnouti & A. David Rodrigues. (2017) Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides. Drug Metabolism and Disposition 45:7, pages 721-733.
Crossref
Crossref
Mariline Gameiro, Renata Silva, Carolina Rocha-Pereira, Helena Carmo, Félix Carvalho, Maria Bastos & Fernando Remião. (2017) Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP. Molecules 22:4, pages 600.
Crossref
Crossref
Beth Williamson, Mathias Lorbeer, Michael D. Mitchell, Timothy G. Brayman & Robert J. Riley. (2016)
Evaluation of a novel PXR-knockout in HepaRG
™
cells
. Pharmacology Research & Perspectives 4:5, pages e00264.
Crossref
Crossref
Margarida EstudanteGraça Soveral, José G. MoraisLeslie Z. Benet. (2016) Insights into solute carriers: physiological functions and implications in disease and pharmacokinetics. MedChemComm 7:8, pages 1462-1478.
Crossref
Crossref
Estefanía Egido, Rita Müller, Xiaochun Li-Blatter, Gracia Merino & Anna Seelig. (2015) Predicting Activators and Inhibitors of the Breast Cancer Resistance Protein (ABCG2) and P-Glycoprotein (ABCB1) Based on Mechanistic Considerations. Molecular Pharmaceutics 12:11, pages 4026-4037.
Crossref
Crossref