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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 4
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Research Article

Reactive metabolite activation by CYP2C19-mediated rhein hepatotoxicity

Li-Na HeSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Ai-Hong YangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and ;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, China
,
Tian-Yi CuiSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Yi-Ran ZhaiSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Fang-Liang ZhangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Jun-Xiu ChenSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Chun-Huan JinSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Yao-Wen FanSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Zi-Jun WuSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and
,
Li-Li WangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and ;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, China
&
Xin HeSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, PR China and ;Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, ChinaCorrespondence[email protected]
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Pages 361-372 | Received 25 Sep 2014, Accepted 03 Nov 2014, Published online: 19 Nov 2014

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Danfei Chen, Shunping Han, Yongqin Zhu, Fang Hu, Yinghui Wei & Guowei Wang. (2018) Kidney-targeted drug delivery via rhein-loaded polyethyleneglycol-co-polycaprolactone-co-polyethylenimine nanoparticles for diabetic nephropathy therapy. International Journal of Nanomedicine 13, pages 3507-3527.
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Yue Zhang, Hui Kong, Xiaoman Liu, Jinjun Cheng, Meiling Zhang, Yongzhi Wang, Fang Lu, Huihua Qu & Yan Zhao. (2018) Quantum dot-based lateral-flow immunoassay for rapid detection of rhein using specific egg yolk antibodies. Artificial Cells, Nanomedicine, and Biotechnology 46:8, pages 1685-1693.
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Ai-Hong Yang, Lei Zhang, De-Xian Zhi, Wen-Li Liu, Xue Gao & Xin He. (2018) Identification and analysis of the reactive metabolites related to the hepatotoxicity of safrole. Xenobiotica 48:11, pages 1164-1172.
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