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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 11
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Pharmacogenetics

In vitro functional analysis of 24 novel CYP2C19 variants recently found in the Chinese Han population

Da-Peng DaiThe Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China,
,
Li-Ming HuDepartment of Pharmacy, The First People's Hospital of Wenling, Wenling, Zhejiang, China,
,
Pei-Wu GengThe Laboratory of Clinical Pharmacy, The People’s Hospital of Lishui, Lishui, Zhejiang, China, and
,
Shuang-Hu WangThe Laboratory of Clinical Pharmacy, The People’s Hospital of Lishui, Lishui, Zhejiang, China, and
,
Jie CaiThe Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China, ;Department of Pharmacology, School of Pharmacy, Wenzhou Medical University, Zhejiang, Wenzhou, China
,
Guo-Xin HuDepartment of Pharmacology, School of Pharmacy, Wenzhou Medical University, Zhejiang, Wenzhou, ChinaCorrespondence[email protected]
&
Jian-Ping CaiThe Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China, Correspondence[email protected]
 show all
Pages 1030-1035 | Received 03 Feb 2015, Accepted 09 Mar 2015, Published online: 07 Jul 2015

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Ren-ai Xu, Er-min Gu, Teng-hui Liu, Qiu-geng Ou-yang, Guo-xin Hu & Jian-ping Cai. (2018) The effects of cytochrome P450 2C19 polymorphism on the metabolism of voriconazole in vitro. Infection and Drug Resistance 11, pages 2129-2135.
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Articles from other publishers (9)

Ling-Jing Yuan, Xiang-Yu Li, Jin-Huan Ni, Jing Wang, Xiao-Yu Xu, Jian-Chao Luo, Qi Zhou, Guo-Xin Hu, Jian-Ping Cai & Jian-Chang Qian. (2023) Functional evaluation of CYP2C19 and CYP3A4 gene polymorphism on ibuprofen metabolism. Toxicology and Applied Pharmacology 475, pages 116653.
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Mitra Samadi, Laleh Beigi, Fatemeh Yadegari, Alireza Madjid Ansari, Keivan Majidzadeh-A, Maryam Eskordi & Leila Farahmand. (2022) Recognition of functional genetic polymorphism using ESE motif definition: a conservative evolutionary approach to CYP2D6/CYP2C19 gene variants. Genetica 150:5, pages 289-297.
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Tian Lan, Ya-Qing Ma, Ya-Min Dang, Chen-Chen Wang, Ren-Ai Xu, Jian-Ping Cai & Guo-Xin Hu. (2021) Effects of 31 recombinant CYP2C19 variants on clomipramine metabolism in vitro. Journal of Psychopharmacology 35:12, pages 1517-1522.
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Mariana R. Botton, Michelle Whirl‐Carrillo, Andria L. Del Tredici, Katrin Sangkuhl, Larisa H. Cavallari, José A. G. Agúndez, Jorge Duconge, Ming Ta Michael Lee, Erica L. Woodahl, Karla Claudio‐Campos, Ann K. Daly, Teri E. Klein, Victoria M. Pratt, Stuart A. Scott & Andrea Gaedigk. (2020) PharmVar GeneFocus: CYP2C19 . Clinical Pharmacology & Therapeutics 109:2, pages 352-366.
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Tingting Wang, Ting Zhao, Sichen Bao, Li Jia, Jie Feng, Aiping Yu, Li Sun, Xihong Guo, Hongjian Li & Luhai Yu. (2020) CYP2C19, PON1, and ABCB1 gene polymorphisms in Han and Uygur populations with coronary artery disease in Northwestern Xinjiang, China, From 2014 Through 2019. Medicine 99:29, pages e20582.
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Vanessa Gonzalez-Covarrubias, Marlet Morales-Franco, Omar F. Cruz-Correa, Angélica Martínez-Hernández, Humberto García-Ortíz, Francisco Barajas-Olmos, Alma Delia Genis-Mendoza, José Jaime Martínez-Magaña, Humberto Nicolini, Lorena Orozco & Xavier Soberón. (2019) Variation in Actionable Pharmacogenetic Markers in Natives and Mestizos From Mexico. Frontiers in Pharmacology 10.
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Hongzhi Zhao, Jiufeng Li, Yanqiu Zhou, Lin Zhu, Yuanyuan Zheng, Wei Xia, Yuanyuan Li, Li Xiang, Wei Chen, Shunqing Xu & Zongwei Cai. (2018) Investigation on Metabolism of Di(2-Ethylhexyl) Phthalate in Different Trimesters of Pregnant Women. Environmental Science & Technology 52:21, pages 12851-12858.
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Xiao‐Yang Zhou, Xiao‐Xia Hu, Meng‐Fang Li, Hao Wang, Li‐Qun Zhang, Guo‐Xin Hu & Jian‐Ping Cai. (2017) Functional characterization of CYP2C19 variants in nebivolol 4‐hydroxlation in vitro. Drug Testing and Analysis 10:5, pages 807-813.
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Ping Fang, Jia-Yang He, Ai-Xia Han, Tian Lan, Da-Peng Dai, Jian-Ping Cai & Guo-Xin Hu. (2017) Effects of CYP2C19 Variants on Fluoxetine Metabolism in vitro. Pharmacology 100:1-2, pages 91-97.
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