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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 11
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General Xenobiochemistry

In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7

Larry HouseDepartment of Medicine, University of Chicago, Chicago, IL, USA
,
Jacqueline RamirezDepartment of Medicine, University of Chicago, Chicago, IL, USA
,
Michael SeminerioDepartment of Medicine, University of Chicago, Chicago, IL, USA
,
Snezana MirkovDepartment of Medicine, University of Chicago, Chicago, IL, USA
&
Mark J. RatainDepartment of Medicine, University of Chicago, Chicago, IL, USACorrespondence[email protected]
Pages 990-998 | Received 24 Feb 2015, Accepted 04 Apr 2015, Published online: 08 Jun 2015

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Yixuan Li, Weihua Zhang, Tingting Yin, Ce Wang, Feige Wang, Jing Sun, Lina Liu, Qinghuai Zhang & Chunze Zhang. (2020) Inhibition of UDP-glucuronosyltransferases by different furoquinoline alkaloids. Xenobiotica 50:10, pages 1170-1179.
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Xin Liu, Yun-Feng Cao, Pei-Pei Dong, Liang-Liang Zhu, Zhenying Zhao, Xue Wu, Zhi-Wei Fu, Chun-Ting Huang, Zhong-Ze Fang & Hong-Zhi Sun. (2017) The inhibition of UDP-glucuronosyltransferases (UGTs) by vitamin A. Xenobiotica 47:5, pages 376-381.
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Articles from other publishers (6)

Shelby Coates & Philip Lazarus. (2023) Hydrocodone, Oxycodone, and Morphine Metabolism and Drug–Drug Interactions. Journal of Pharmacology and Experimental Therapeutics 387:2, pages 150-169.
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P. Venkata Ramana. (2023) Experimental spectroscopic and molecular docking investigations of the anticancer drugs aprepitant and capecitabine. Theoretical Chemistry Accounts 142:11.
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Werner Bomann, Helen Tinwell, Peter Jenkinson & Felix M. Kluxen. (2021) Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via uridine 5′-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation. Regulatory Toxicology and Pharmacology 122, pages 104884.
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Peng Mou, HuiJun Wang, Liping An, Qiang Yin & Juan Chang. (2018) RS7435335 located in the UGT2B7 gene may be a possible genetic marker for the clinical response and prognosis of breast cancer patients receiving neoadjuvant chemotherapy. Journal of Cellular Biochemistry 120:5, pages 7167-7173.
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Grégoire Narjoux, Justine Clarenne, Brahim Azzouz, Pauline‐Saraï Zeller, Florian Slimano & Olivier Bouché. (2018) Nightmares and hallucinations with aprepitant and opium powder: a suspected drug–drug interaction. British Journal of Clinical Pharmacology 85:2, pages 454-456.
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Helinä Kahma, Anne M. Filppula, Mikko Neuvonen, E. Katriina Tarkiainen, Aleksi Tornio, Mikko T. Holmberg, Matti K. Itkonen, Moshe Finel, Pertti J. Neuvonen, Mikko Niemi & Janne T. Backman. (2018) Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions   . Drug Metabolism and Disposition 46:2, pages 141-150.
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