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Xenobiotica
the fate of foreign compounds in biological systems
Volume 46, 2016 - Issue 5
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General Xenobiochemistry

Effect of CYP2D6 variants on venlafaxine metabolism in vitro

Yun-Yun ZhanSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and
,
Bing-Qing LiangSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and
,
Hao WangSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and
,
Zhen-He WangSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and
,
Qing-Hua WengSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and
,
Da-Peng DaiThe Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, China
,
Jian-Ping CaiThe Key Laboratory of Geriatrics, Beijing Hospital & Beijing Institute of Geriatrics, Ministry of Health, Beijing, ChinaCorrespondence[email protected]
&
Guo-Xin HuSchool of Pharmacy, Wenzhou Medical University, Wenzhou, China and Correspondence[email protected]
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Pages 424-429 | Received 16 Jul 2015, Accepted 28 Aug 2015, Published online: 25 Sep 2015

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Ping Fang, Xiang Zheng, Jiayang He, Honglei Ge, Pengfei Tang, Jianping Cai & Guoxin Hu. (2017) Functional characterization of wild-type and 24 CYP2D6 allelic variants on gefitinib metabolism in vitro. Drug Design, Development and Therapy 11, pages 1283-1290.
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Sarah D. Burris-Hiday, Cara L. Loomis, Alaina M. Richard & Emily E. Scott. 2023. Steroid Biochemistry. Steroid Biochemistry 3 38 .
Lauren M. Behlke, Eric J. Lenze, Vy Pham, J. Philip Miller, Timothy W. Smith, Yasmina Saade, Jordan F. Karp, Charles F. Reynolds, Daniel M. Blumberger, Cristiana Stefan & Benoit H. Mulsant. (2020) The Effect of Venlafaxine on Electrocardiogram Intervals During Treatment for Depression in Older Adults. Journal of Clinical Psychopharmacology 40:6, pages 553-559.
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Naixing Zhang, Lei Ji, Zhixuan Chen, Lin An, Decheng Ren, Yan Bi, Zhenming Guo, Ruixue Yuan, Fan Yuan, Zaiquan Dong, Li Yin, Xueli Sun, Fengping Yang, Xingwang Li, Tao Yu, Lin He, Lei Shi & Guang He. (2020) No association between CYP2C19 genetic polymorphism with treatment remission to antidepressant venlafaxine in Han Chinese population. Psychiatric Genetics 30:1, pages 30-33.
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Amelia Nathania Dong, Nafees Ahemad, Yan Pan, Uma Devi Palanisamy, Beow Chin Yiap & Chin Eng Ong. (2019) Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition. Naunyn-Schmiedeberg's Archives of Pharmacology 392:8, pages 1015-1029.
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Thais Guimarães Martins Nery, Esdras Matheus Silva, Raphael Tavares & Fabio Passetti. (2018) The Challenge to Search for New Nervous System Disease Biomarker Candidates: the Opportunity to Use the Proteogenomics Approach. Journal of Molecular Neuroscience 67:1, pages 150-164.
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Tian Lan, Xiao-Xia Hu, Bing-Qing Liang, Wen-He Pan, Quan Zhou, Ling-Jing Yuan & Guo-Xin Hu. (2016) The Effect of Myricetin on Pharmacokinetics of Atomoxetine and its Metabolite 4-Hydroxyatomoxetine In Vivo and In Vitro. European Journal of Drug Metabolism and Pharmacokinetics 42:2, pages 261-268.
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Jie Gao, Xin Tian, Jun Zhou, Ming-Zhu Cui, Hai-Feng Zhang, Na Gao, Qiang Wen & Hai-Ling Qiao. (2017) From Genotype to Phenotype: Cytochrome P450 2D6-Mediated Drug Clearance in Humans. Molecular Pharmaceutics 14:3, pages 649-657.
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X. Hu, T. Lan, D. Dai, R.-a. Xu, L. Yuan, Q. Zhou, Y. Li, J. Cai & G. Hu. (2016) Evaluation of 24 CYP2D6 Variants on the Metabolism of Nebivolol In Vitro. Drug Metabolism and Disposition 44:11, pages 1828-1831.
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Ying SuBing-qing LiangYan-lin FengYunyun ZhanErmin GuXinxin ChenDa-Peng DaiGuo-xin HuJian-ping Cai. (2016) Assessment of 25 CYP2D6 alleles found in the Chinese population on propafenone metabolism in vitro . Canadian Journal of Physiology and Pharmacology 94:8, pages 895-899.
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Xiao-Xia Hu, Quan Zhou, Tian Lan, Xiang-Xin Huang, Bing-qing Liang, Da-Peng Dai, Jian-Ping Cai & Guo-Xin Hu. (2016) Functional characterization of 22 novel CYP2D6 variants for the metabolism of Tamoxifen. Journal of Pharmacy and Pharmacology 68:6, pages 819-825.
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Bingqing Liang, Yunyun Zhan, Ying Wang, Ermin Gu, Dapeng Dai, Jianping Cai & Guoxin Hu. (2016) Effect of 24 Cytochrome P450 2D6 Variants Found in the Chinese Population on Atomoxetine Metabolism in vitro. Pharmacology 97:1-2, pages 78-83.
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