Citations (14)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (8)
Hidetaka Kamimura, Shotaro Uehara, Nao Yoneda & Hiroshi Suemizu. (2023) Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css–MRTpo method and chimeric mice with humanised livers. Xenobiotica 53:8-9, pages 523-535.
Read now
Read now
Shogo Matsumoto, Hidetaka Kamimura, Megumi Nishiwaki, Naoki Cho, Kazuhiko Kato & Taichi Yamamoto. (2021) Empirical and theoretical approaches for the prediction of human hepatic clearance using chimeric mice with humanised liver: the use of physiologically based scaling, a novel solution for potential overprediction due to coexisting mouse metabolism. Xenobiotica 51:9, pages 983-994.
Read now
Read now
Hidetaka Kamimura, Shotaro Uehara & Hiroshi Suemizu. (2020) A novel Css-MRTpo approach to simulate oral plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite in humans using chimeric mice with humanized livers. Xenobiotica 50:7, pages 761-768.
Read now
Read now
Shotaro Uehara, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki & Hiroshi Suemizu. (2020) Metabolism of desloratadine by chimeric TK-NOG mice transplanted with human hepatocytes. Xenobiotica 50:6, pages 733-740.
Read now
Read now
Hiroshi Iwata, Masatomo Goto, Norifumi Sakai, Hiroshi Suemizu & Hiroshi Yamazaki. (2019) Predictability of human pharmacokinetics of diisononyl phthalate (DINP) using chimeric mice with humanized liver. Xenobiotica 49:11, pages 1311-1322.
Read now
Read now
Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroshi Yamazaki & Hiroshi Suemizu. (2019) Expression and inducibility of cytochrome P450s in human hepatocytes isolated from chimeric mice with humanised livers. Xenobiotica 49:6, pages 678-687.
Read now
Read now
Keigo Nakayama, Soichiro Ito, Masahiro Suzuki, Hiroaki Takubo, Hiroshi Yamazaki & Yukihiro Nomura. (2019) Prediction of human pharmacokinetics of typical compounds by a physiologically based method using chimeric mice with humanized liver. Xenobiotica 49:4, pages 404-414.
Read now
Read now
Hidetaka Kamimura, Satoshi Ito, Hiroyuki Chijiwa, Takeshi Okuzono, Tomohiro Ishiguro, Yosuke Yamamoto, Sho Nishinoaki, Shin-Ichi Ninomiya, Marina Mitsui, Amit S. Kalgutkar, Hiroshi Yamazaki & Hiroshi Suemizu. (2017) Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling. Xenobiotica 47:5, pages 382-393.
Read now
Read now
Articles from other publishers (6)
Shotaro Uehara, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki & Hiroshi Suemizu. (2020) Human Aldehyde Oxidase 1–Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metabolism and Disposition 48:7, pages 580-586.
Crossref
Crossref
Jing-Zhang Wang, Nan-Yan Xiong, Li-Zhen Zhao, Jin-Tian Hu, De-Cheng Kong & Jiang-Yong Yuan. (2018) Review fantastic medical implications of 3D-printing in liver surgeries, liver regeneration, liver transplantation and drug hepatotoxicity testing: A review. International Journal of Surgery 56, pages 1-6.
Crossref
Crossref
Daisuke Satoh, Satoshi Abe, Kaoru Kobayashi, Yoshihiro Nakajima, Mitsuo Oshimura & Yasuhiro Kazuki. (2018) Human and mouse artificial chromosome technologies for studies of pharmacokinetics and toxicokinetics. Drug Metabolism and Pharmacokinetics 33:1, pages 17-30.
Crossref
Crossref
Yoichi Naritomi, Seigo Sanoh & Shigeru Ohta. (2018) Chimeric mice with humanized liver: Application in drug metabolism and pharmacokinetics studies for drug discovery. Drug Metabolism and Pharmacokinetics 33:1, pages 31-39.
Crossref
Crossref
Eiko Suzuki, Kumiko Koyama, Daisuke Nakai, Ryoya Goda, Hiroshi Kuga & Kan Chiba. (2017) Observation of Clinically Relevant Drug Interaction in Chimeric Mice with Humanized Livers: The Case of Valproic Acid and Carbapenem Antibiotics. European Journal of Drug Metabolism and Pharmacokinetics 42:6, pages 965-972.
Crossref
Crossref
Naoyuki Nakada. (2017) Evaluation of the Utility of Chimeric Mice with Humanized Livers for the Characterization and Profiling of the Metabolites of a Selective Inhibitor (YM543) of the Sodium-Glucose Cotransporter 2. Pharmaceutical Research 34:4, pages 874-886.
Crossref
Crossref