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Yasuhiro Uno, Yutaro Noda, Saho Morikuni, Norie Murayama & Hiroshi Yamazaki. (2023) Liver microsomal cytochrome P450 3A-dependent drug oxidation activities in individual dogs. Xenobiotica 53:3, pages 140-148.
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Akiko Toda, Makiko Shimizu, Shotaro Uehara, Tatsuro Sasaki, Tomonori Miura, Masayuki Mogi, Masahiro Utoh, Hiroshi Suemizu & Hiroshi Yamazaki. (2021) Plasma and hepatic concentrations of acetaminophen and its primary conjugates after oral administrations determined in experimental animals and humans and extrapolated by pharmacokinetic modeling. Xenobiotica 51:3, pages 316-323.
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Akiko Toda, Shotaro Uehara, Takashi Inoue, Masahiro Utoh, Takashi Kusama, Makiko Shimizu, Yasuhiro Uno, Masayuki Mogi, Erika Sasaki & Hiroshi Yamazaki. (2018) Effects of aging and rifampicin pretreatment on the pharmacokinetics of human cytochrome P450 probes caffeine, warfarin, omeprazole, metoprolol and midazolam in common marmosets genotyped for cytochrome P450 2C19. Xenobiotica 48:7, pages 720-726.
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Masahiro Utoh, Takashi Kusama, Tomonori Miura, Marina Mitsui, Mirai Kawano, Takahiro Hirano, Makiko Shimizu, Yasuhiro Uno & Hiroshi Yamazaki. (2018) R-warfarin clearances from plasma associated with polymorphic cytochrome P450 2C19 and simulated by individual physiologically based pharmacokinetic models for 11 cynomolgus monkeys. Xenobiotica 48:2, pages 206-210.
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Miho Yamazaki-Nishioka, Makiko Shimizu, Hiroshi Suemizu, Megumi Nishiwaki, Marina Mitsui & Hiroshi Yamazaki. (2018) Human plasma metabolic profiles of benzydamine, a flavin-containing monooxygenase probe substrate, simulated with pharmacokinetic data from control and humanized-liver mice. Xenobiotica 48:2, pages 117-123.
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Makiko Shimizu, Hiroshi Suemizu, Marina Mitsui, Norio Shibata, F. Peter Guengerich & Hiroshi Yamazaki. (2017) Metabolic profiles of pomalidomide in human plasma simulated with pharmacokinetic data in control and humanized-liver mice. Xenobiotica 47:10, pages 844-848.
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Hidetaka Kamimura, Satoshi Ito, Hiroyuki Chijiwa, Takeshi Okuzono, Tomohiro Ishiguro, Yosuke Yamamoto, Sho Nishinoaki, Shin-Ichi Ninomiya, Marina Mitsui, Amit S. Kalgutkar, Hiroshi Yamazaki & Hiroshi Suemizu. (2017) Simulation of human plasma concentration–time profiles of the partial glucokinase activator PF-04937319 and its disproportionate N-demethylated metabolite using humanized chimeric mice and semi-physiological pharmacokinetic modeling. Xenobiotica 47:5, pages 382-393.
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Masahiro Utoh, Hiroshi Suemizu, Marina Mitsui, Mirai Kawano, Akiko Toda, Shotaro Uehara, Yasuhiro Uno, Makiko Shimizu, Erika Sasaki & Hiroshi Yamazaki. (2016) Human plasma concentrations of cytochrome P450 probe cocktails extrapolated from pharmacokinetics in mice transplanted with human hepatocytes and from pharmacokinetics in common marmosets using physiologically based pharmacokinetic modeling. Xenobiotica 46:12, pages 1049-1055.
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Articles from other publishers (7)
Eva Sanchez-Quant, Maria Lucia Richter, Maria Colomé-Tatché & Celia Pilar Martinez-Jimenez. (2023) Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge. Genome Biology 24:1.
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Marilyn N. Martinez, Jonathan P. Mochel, Sibylle Neuhoff & Devendra Pade. (2021) Comparison of Canine and Human Physiological Factors: Understanding Interspecies Differences that Impact Drug Pharmacokinetics. The AAPS Journal 23:3.
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Makiko Kuwagata, Takuro Hasegawa, Hiromasa Takashima, Makiko Shimizu, Satoshi Kitajima & Hiroshi Yamazaki. (2021) Pharmacokinetics of primary metabolites 5-hydroxythalidomide and 5′-hydroxythalidomide formed after oral administration of thalidomide in the rabbit, a thalidomide-sensitive species. The Journal of Toxicological Sciences 46:12, pages 553-560.
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Miriam Ayuso, Laura Buyssens, Marina Stroe, Allan Valenzuela, Karel Allegaert, Anne Smits, Pieter Annaert, Antonius Mulder, Sebastien Carpentier, Chris Van Ginneken & Steven Van Cruchten. (2020) The Neonatal and Juvenile Pig in Pediatric Drug Discovery and Development. Pharmaceutics 13:1, pages 44.
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Marilyn N. Martinez, Jonathan P. Mochel & Devendra Pade. (2020) Considerations in the extrapolation of drug toxicity between humans and dogs. Current Opinion in Toxicology 23-24, pages 98-105.
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Huadong Tang & Michael Mayersohn. (2018) Porcine Prediction of Pharmacokinetic Parameters in People: A Pig in a Poke?. Drug Metabolism and Disposition 46:11, pages 1712-1724.
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Hiroshi Yamazaki, Hiroshi Suemizu, Marina Mitsui, Makiko Shimizu & F. Peter Guengerich. (2016) Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, and Physiologically-Based Pharmacokinetic Modeling in Toxicology. Chemical Research in Toxicology 29:12, pages 1903-1911.
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