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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 2
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Molecular Toxicology

Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin

Leiyan HeInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and ;School of Pharmaceutical Sciences, Central South University, Changsha, China
,
Yaoxue GuoInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and ;School of Pharmaceutical Sciences, Central South University, Changsha, China
,
Ye DengInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and ;School of Pharmaceutical Sciences, Central South University, Changsha, China
,
Chun LiInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and ;School of Pharmaceutical Sciences, Central South University, Changsha, China
,
Chengzi ZuoInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and
&
Wenxing PengInstitute of Clinical Pharmacy and Pharmacology, Second Xiangya Hospital, Central South University, Changsha, China and Correspondence[email protected]
Pages 154-163 | Received 13 Jan 2016, Accepted 26 Feb 2016, Published online: 24 Jan 2017

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Nannan Wang, Xinyu Chen, Zhuolu Hao, Honggang Yi & Shaowen Tang. (2022) Association of ABCG2 polymorphisms with susceptibility to anti-tuberculosis drug-induced hepatotoxicity in the Chinese population. Xenobiotica 52:5, pages 527-533.
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Ning Wang, Shaochen Guo, Haiting Liu, Yangming Ding, Rong Yao, Zhongquan Liu, Hui Zhu, Xi Chen, Xinting Yang, Xiaoyou Chen & Yu Lu. (2022) Relevance of gene polymorphisms of NAT2 and NR1I2 to anti-tuberculosis drug-induced hepatotoxicity. Xenobiotica 52:5, pages 520-526.
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Articles from other publishers (13)

Jyoti Rani, Sanju Bala Dhull, Pawan Kumar Rose & Mohd. Kashif Kidwai. (2024) Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: a metabolic mechanism perspective. Phytomedicine 122, pages 155142.
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Yilin Sun, Yuanyue Zhang, Nan Ma & Shengbao Cai. (2023) Rhus chinensis Mill. fruits alleviate liver injury induced by isoniazid and rifampicin through regulating oxidative stress, apoptosis, and bile acid transport. Journal of Ethnopharmacology 310, pages 116387.
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Xiuping Zhuang, Li Li, Tianyi Liu, Rui Zhang, Peimin Yang, Xin Wang & Long Dai. (2022) Mechanisms of isoniazid and rifampicin-induced liver injury and the effects of natural medicinal ingredients: A review. Frontiers in Pharmacology 13.
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Yun Li, Wen‐wen Luo, Xuan Cheng, Huai‐rong Xiang, Bei He, Qi‐zhi Zhang & Wen‐xing Peng. (2022) Curcumin attenuates isoniazid‐induced hepatotoxicity by upregulating the SIRT1/PGC‐1α/NRF1 pathway. Journal of Applied Toxicology 42:7, pages 1192-1204.
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Nilakshi Barua & Alak Kumar Buragohain. (2021) Therapeutic Potential of Curcumin as an Antimycobacterial Agent. Biomolecules 11:9, pages 1278.
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Qiang Su, Wei Kuang, Weiyi Hao, Jing Liang, Liang Wu, Chunmei Tang, Yali Wang & Tao Liu. (2021) Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes. Mediators of Inflammation 2021, pages 1-13.
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Miaomiao Yang, Yunliang Qiu, Yanyu Jin, Wenpei Liu, Qingliang Wang, Honggang Yi & Shaowen Tang. (2020) NR1I2 genetic polymorphisms and the risk of anti‐tuberculosis drug‐induced hepatotoxicity: A systematic review and meta‐analysis. Pharmacology Research & Perspectives 8:6.
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Miaomiao Yang, Hongqiu Pan, Hongbo Chen, Wenpei Liu, Lihuan Lu, Xiaomin He, Honggang Yi & Shaowen Tang. (2020) Association between NR1I2 polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity in an Eastern Chinese Han population: A case-control study. Infection, Genetics and Evolution 83, pages 104349.
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Xiao-hua Wang, Yong-wen Jin, Zhi Rao, Guo-qiang Zhang, Kai-hong Zang & Hong-yan Qin. (2019) Curcumin Enhances the Systemic Exposure of Isoniazid in Rats: Role of NAT2 in the Liver and Intestine. International Journal of Pharmacology 16:1, pages 10-17.
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Akinori Takemura, Simin Gong, Shuichi Sekine & Kousei Ito. (2019) Inhibition of biliary network reconstruction by benzbromarone delays recovery from pre-existing liver injury. Toxicology 423, pages 32-41.
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Yifan Bao, Xiaochao Ma, Theodore P. Rasmussen & Xiao-bo Zhong. (2018) Genetic Variations Associated with Anti-Tuberculosis Drug-Induced Liver Injury. Current Pharmacology Reports 4:3, pages 171-181.
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Ji Wang, Chunying Wang & Gaofeng Bu. (2018) Curcumin inhibits the growth of liver cancer stem cells through the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway. Experimental and Therapeutic Medicine.
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Yilin Sun, Yuanyue Zhang, Nan Ma & Shengbao Cai. (2022) Rhus Chinensis Mill. Fruits Alleviate Liver Injury Induced by Isoniazid and Rifampicin Through Adjusting Several Crucial Proteins in Mice. SSRN Electronic Journal.
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