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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 2
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General Xenobiochemistry

Oxidative bioactivation of nitrofurantoin in rat liver microsomes

Hui LiSchool of Pharmacy,
,
Dongju LinSchool of Pharmacy,
,
Ying PengSchool of Pharmacy, Correspondence[email protected]
&
Jiang ZhengKey Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, Shenyang Pharmaceutical University, Shenyang, Liaoning, China, and ;Division of Gastroenterology and Hepatology, Department of Pediatrics, Center for Developmental Therapeutics, Seattle Children’s Research Institute, University of Washington School of Medicine, Seattle, WA, USACorrespondence[email protected]
Pages 103-111 | Received 18 Jan 2016, Accepted 08 Mar 2016, Published online: 19 Apr 2016

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Aušra Nemeikaitė-Čėnienė, Audronė Marozienė, Lina Misevičienė, Jelena Tamulienė, Aliaksei V. Yantsevich & Narimantas Čėnas. (2021) Flavoenzyme-catalyzed single-electron reduction of nitroaromatic antiandrogens: implications for their cytotoxicity. Free Radical Research 55:3, pages 246-254.
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Articles from other publishers (7)

Aušra Nemeikaitė-Čėnienė, Lina Misevičienė, Audronė Marozienė, Violeta Jonušienė & Narimantas Čėnas. (2023) Enzymatic Redox Properties and Cytotoxicity of Irreversible Nitroaromatic Thioredoxin Reductase Inhibitors in Mammalian Cells. International Journal of Molecular Sciences 24:15, pages 12460.
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Ridho Asra & Alan M Jones. (2023) Green electrosynthesis of drug metabolites. Toxicology Research 12:2, pages 150-177.
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M. Teresa Donato, Gloria Gallego-Ferrer & Laia Tolosa. (2022) In Vitro Models for Studying Chronic Drug-Induced Liver Injury. International Journal of Molecular Sciences 23:19, pages 11428.
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Min Tian, Ying Peng & Jiang Zheng. (2022) Metabolic Activation and Hepatotoxicity of Furan-Containing Compounds. Drug Metabolism and Disposition 50:5, pages 655-670.
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Narimantas Čėnas, Aušra Nemeikaitė-Čėnienė & Lidija Kosychova. (2021) Single- and Two-Electron Reduction of Nitroaromatic Compounds by Flavoenzymes: Mechanisms and Implications for Cytotoxicity. International Journal of Molecular Sciences 22:16, pages 8534.
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Hui Li, Zhengyu Zhang, Xiaojing Yang, Xu Mao, Ying Wang, Jian Wang, Ying Peng & Jiang Zheng. (2019) Electron Deficiency of Nitro Group Determines Hepatic Cytotoxicity of Nitrofurantoin. Chemical Research in Toxicology 32:4, pages 681-690.
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Yassir Lekbach, Dake Xu, Soumya El Abed, Yuqiao Dong, Dan Liu, M. Saleem Khan, Saad Ibnsouda Koraichi & Ke Yang. (2018) Mitigation of microbiologically influenced corrosion of 304L stainless steel in the presence of Pseudomonas aeruginosa by Cistus ladanifer leaves extract. International Biodeterioration & Biodegradation 133, pages 159-169.
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