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Xenobiotica
the fate of foreign compounds in biological systems
Volume 1, 1971 - Issue 3
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Research Article

Additional Route in the Metabolism of Sulphanilamide

Wolfgang Fries Pharmakologisches Institut der Universität München, München, W Germany
,
Manfred Kiese Pharmakologisches Institut der Universität München, München, W Germany
&
Werner Lenk Pharmakologisches Institut der Universität München, München, W Germany
Pages 241-255 | Received 28 Jun 1971, Published online: 15 Sep 2008

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Toby J. Athersuch, Ian D. Wilson, Hector C. Keun & John C. Lindon. (2013) Development of quantitative structure-metabolism (QSMR) relationships for substituted anilines based on computational chemistry. Xenobiotica 43:9, pages 792-802.
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G. B. Scarfe, I. D. Wilson, M. A. Warne, E. Holmes, J. K. Nicholson & J. C. Lindon. (2002) Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry. Xenobiotica 32:4, pages 267-277.
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G. B. Scarfe, J. K. Nicholson, J. C. Lindon, I. D. Wilson, S. Taylor, E. Clayton & B. Wright. (2002) Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat. Xenobiotica 32:4, pages 325-337.
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G. B. SCARFE, B. WRIGHT, E. CLAYTON, S. TAYLOR, I. D. WILSON, J. C. LINDON & J. K. NICHOLSON. (1998) 19F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4- trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling. Xenobiotica 28:4, pages 373-388.
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D. Hesk, D. H. Hutson & C. J. Logan. (1988) The fate of 4-cyanoacetanilide in rats and mice; mechanism of formation of a novel electrophilic metabolite. Xenobiotica 18:8, pages 955-966.
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Charlotte Ressler & MicheleM. Knapp. (1985) Liquid Chromatography of Oxidized Sulfanilamide Derivatives. Journal of Liquid Chromatography 8:8, pages 1445-1453.
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S. McLean, Heather Galloway, S. Butler, D. Whittle & S. C. Nicol. (1983) Acetylation of sulphanilamide in four marsupials and a monotreme. Xenobiotica 13:2, pages 81-85.
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G. E. Smith & L. A. Griffiths. (1974) Metabolism of N-Acylated and O-Alkylated Drugs by the Intestinal Microflora During Anaerobic Incubation in vitro. Xenobiotica 4:8, pages 477-487.
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Wolfgang Fries, Manfred Kiese & Werner Lenk. (1973) Oxidation of Polycyclic N -Arylacetamides to Glycol-amides and Hydroxamic Acids in Rabbits. Xenobiotica 3:8, pages 525-540.
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Articles from other publishers (6)

Michael E. Ford, T.A.Michael Johnson, J.E. Premecz & C.A. Cooper. (1988) Catalytic Dimerization of Monoethanolamine to N-(2-aminoethyl)- ethanolamine. Journal of Molecular Catalysis 44:2, pages 207-211.
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I.D. Wilson, C.M. Macdonald, J.M. Fromson, J.A. Troke & D. Hillbeck. (1985) Species differences in the metabolism of 14C-p-trifluoromethylaniline: Production of an oxanilic acid as the major metabolite by the rat. Biochemical Pharmacology 34:11, pages 2025-2028.
Crossref
Werner Lenk. (1979) Mixed function oxygenation of the lower fatty acyl residues—I. Hydroxylation of the acetic, propionic, butyric, and valeric residues by rabbit liver microsomes. Biochemical Pharmacology 28:14, pages 2149-2159.
Crossref
Lance R. Pohl & Gopal Krishna. (1978) Study of the mechanism of metabolic activation of chloramphenicol by rat liver microsomes. Biochemical Pharmacology 27:3, pages 335-341.
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Manfred Kiese & Werner Lenk. (1973) ω-And (ω-1)-hydroxylation of 4-chloropropionanilide by rabbits and rabbit liver microsomes. Biochemical Pharmacology 22:20, pages 2565-2574.
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S. Archer, A. Yarinsky, G. W. Camiener, W. J. Wechter, J. W. McFarland, A. J. Gordon, S. G. Gilgore, I. Izquierdo, A. G. Nasello, W. Lenk, W. A. Zygmunt, P. A. Tavormina, J. A. Izquierdo & R. KleineW. Lenk. 1972. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques 229 308 .

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