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Xenobiotica
the fate of foreign compounds in biological systems
Volume 1, 1971 - Issue 6
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Research Article

The Enzymic Formation of a Methylenedioxyphenyl Derivative Exhibiting an Isocyanide-like Spectrum with Reduced Cytochrome P-450 in Hepatic Microsomes

Pages 581-591 | Received 30 Jul 1971, Published online: 14 Oct 2008

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Read on this site (21)

Tingting Zhang, Jinqiu Rao, Wei Li, Kai Wang & Feng Qiu. (2020) Mechanism-based inactivation of cytochrome P450 enzymes by natural products based on metabolic activation. Drug Metabolism Reviews 52:4, pages 501-530.
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K. Venkatakrishnan, R. S. Obach & A. Rostami-Hodjegan. (2007) Mechanism-based inactivation of human cytochrome P450 enzymes: strategies for diagnosis and drug–drug interaction risk assessment. Xenobiotica 37:10-11, pages 1225-1256.
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Paul F. Hollenberg. (2002) Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes. Drug Metabolism Reviews 34:1-2, pages 17-35.
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M. Nakajima, M. Suzuki, R. Yamaji, H. Takashina, N. Shimada, H. Yamazaki & T. Yokoi. (1999) Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. Xenobiotica 29:12, pages 1191-1202.
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Marcel Delaforge, Costas Ioannides & Dennis V. Parke. (1985) Ligand-complex formation between cytochromes P-450 and P-448 and methylenedioxyphenyl compounds. Xenobiotica 15:4, pages 333-342.
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M. Murray, Krystyna Hetnarski & C. F. Wilkinson. (1985) Selective inhibitory interactions of alkoxymethylenedioxybenzenes towards mono-oxygenase activity in rat-hepatic microsomes. Xenobiotica 15:5, pages 369-379.
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C. F. Wilkinson & M. Murray. (1984) Considerations of Toxicologic Interactions in Developing New Chemicals. Drug Metabolism Reviews 15:5-6, pages 897-917.
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S. J. Moloney, B. J. Snider & R. A. Prough. (1984) The interactions of hydrazine derivatives with rat-hepatic cytochrome P-450. Xenobiotica 14:10, pages 803-814.
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W. Lenk & U. Scharmer. (1980) Reaction of microsomal and cytosolic enzymes with N-arylacetohydroxamic acids. Xenobiotica 10:7-8, pages 573-591.
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Ernest Hodgson & Richard M. Philpot. (1975) Interaction of Methylenedioxyphenyl (1,3-Benzodioxole) Compounds with Enzymes and Their Effects on Mammals. Drug Metabolism Reviews 3:1, pages 231-301.
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Michael R. Franklin. (1974) Complexes of Metabolites of Amphetamines with Hepatic Cytochrome P-450. Xenobiotica 4:3, pages 133-142.
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